Sentences with phrase «high sequence divergence»

In this regard, the high sequence divergence of TMAdV relative to the known human / simian adenoviruses (Fig. 3), and comparable sequence similarity in the polymerase gene to a porcine adenovirus (Figs. 3 and S1) are striking.
The poor apparent coverage was the result of high sequence divergence of the TMAdV genome from SAdV - 18, which hindered the identification of most of the 16,524 actual deep sequencing reads derived from TMAdV (Fig. 2B, red).
However, the high sequence divergence in the fiber protein (Table 2), as well as the absence of fiber motifs conserved among adenoviruses that bind CAR [36], [37](coxsackievirus - adenovirus receptor) or CD46 [38], [39], [40](data not shown), suggest that neither of these two human adenoviral receptors may be the attachment receptor for TMAdV.
This is consistent with the higher sequence divergence of the C. elegans daz - 1 RNA binding motif than most other bilaterian Boule homologs (Figure 2).
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