Sentences with phrase «high symptom severity»

Led by Brenda Penninx, PhD, of the VU University Medical Center in Amsterdam, the Netherlands, the study found that patients with an early age at onset and higher symptom severity have an increased genetic risk for MDD, bipolar disorder and schizophrenia.

Results: With the exception of conduct problems, the PDD group generally received higher symptom severity ratings than the regular early childhood group, but the pattern of differences compared with the other two groups often varied by type of symptom and informant.

Direct comparisons between the two groups show that children in the mother and father «Adult» ADHD group have significantly higher symptom severity than those in the mother and father childhood - only group (results available from the first author).

Not exact matches

Urinary incontinence (UI) has an effect on quality of life during the postpartum period.1, 2 Fear of UI is one of the most common reasons for maternal demand for cesarean delivery.3, 4 The muscle strength of the pelvic floor returns to the antepartum value 6 — 10 weeks postpartum in most women.5, 6 However, UI symptoms after delivery do not resolve in the long term in some women.7, 8 Studies have variously concluded that the prevalence of UI changed9 or did not change within 6 months or 1 year postpartum.10, 11 A higher prevalence or incidence of UI has been observed in women who had a vaginal delivery than in women who underwent cesarean delivery.10 — 18 In contrast, a recent study found that vaginal delivery was not associated with postpartum UI.19 The long - term protective effect of cesarean delivery has not been determined.20 Validated and reliable questionnaires to evaluate UI, including severity and quality of life, are needed for postpartum evaluation.21 However, comparisons of UI severity and the effect on daily life between women who have had vaginal and cesarean deliveries are scarce.22

«Higher ragweed pollen concentrations and a longer ragweed pollen season may also increase the severity of symptoms,» he added.

The researchers found a continuum of trauma - related symptom severity across the groups, with highest scores in patients with DID, followed by patients with PTSD, and the lowest scores for healthy controls.

He's consulting with Boehringer Ingelheim, a pharmaceutical company headquartered in Germany, where scientists this fall began offering an experimental drug to people at very high risk of psychosis who are eligible based on the severity of their symptoms.

To study the suitability of guanabenz as a therapeutic after MS symptoms have already appeared and peaked, the researchers used a mouse model in which symptoms relapse and remit — cycling from high severity to low severity to high again over time.

In contrast, higher proline levels were associated with greater negative symptom severity in patients with the Met / Met gene.

In total, the levels of 17 different cytokines seemed to fluctuate with symptom severity: They were lower in people with mild symptoms when compared to the control group, but higher in people with severe symptoms.

Studies comparing IV administration to oral use of vitamin C found that the higher concentrations, only achievable with IV, more effectively and consistently shortened the duration of illness and decreased symptom severity (i.e. reduced incidence of malaise, fever, and chills).

Due to the severity of these tests, they are to be taken in a health care setting and, «if your doctor determines that your blood glucose level is very high, or if you have classic symptoms of high blood glucose in addition to one positive test, your doctor may not require a second test to diagnose diabetes,» according to the American Diabetes Association.

She explained that while Anne's symptoms were no doubt partly related to her conflict over having a baby, the severity of her headaches, depression and weight gain, as well as her cervical dysplasia, had probably been caused by the high doses of estrogen she had been taking, as well as the synthetic progestins.

«What I think the study underlines is the need to consider the severity of ADHD symptoms and the option of non-stimulant treatments for children with high cardiovascular risk.

Higher doses can be given depending on the severity of symptoms.

Our sample can be characterized as high risk (baseline ECBI T score > 55) 42 or at the borderline of clinical (T score > 60), 34 which is typical of previous randomized clinical trials of parent training for young children.41 The results across methods in this study are impressive given that effect sizes have been shown to be associated with the magnitude of symptom severity at baseline, 43 and thus it is typically more difficult to find large effects in prevention than in intervention trials.

At both baseline and follow - up there was a high rate of depressive symptoms with one third of the group scoring 14 or more on the Beck Depression Inventory (a questionnaire designed to measure severity of depressive symptoms).

Results from a one - way MANOVA revealed that patients with a premorbid and current psychiat - ric disorder reported significantly higher pain severity, more somatic symptoms, poorer sleep quality, and poorer quality of life than those with no psychiatric history.

Included studies used several tools for measuring the severity of depressive symptoms, namely the Hamilton Depression Rating Scale (HAM - D), 21 22 30 34 35 Patient Health Questionnaire - 9 (PHQ - 9), 24 36 Geriatric Depression Scale (GDS), 23 26 28 Hopkins Symptom Checklist - 20 (HSCL - 20), 37 38 Montgomery - Asberg Depression Rating Scale (MADRS), 18 25 27 Beck Depression Inventory - Fast Screen (BDI - FS) 39 and Center of Epidemiologic Studies Depression Scale (CES - D).40 These tools have different score ranges (HAM - D = 0 — 53, PHQ - 9 = 0 — 27, GDS = 0 — 15, HSCL - 20 = 0 — 4, MADRS = 0 — 60, BDI - FS = 0 — 21 and CES - D = 0 — 60), with higher scores in all tools representing increasing severity of depressive symptoms.

In a separate examination of the data, we demonstrated that participating in MF - PEP significantly improved the quality of services used, mediated by parents» beliefs about treatment.25 Participating in MF - PEP also significantly improved the severity of children's mood symptoms, mediated by quality of services used.25 Thus, as it was originally designed to do, MF - PEP helps parents become better mental health consumers, and access to higher - quality services results in children's decreased symptom severity.

The score range for the PCL is 17 to 85, with higher scores indicating greater PTSD symptom severity.

Diagnosis of PTSD and symptom severity were established with the Clinician - Administered PTSD Scale (CAPS), 12 a semistructured clinician interview consistent with the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision)(DSM - IV - TR).13 Posttraumatic stress disorder diagnostic status was based on meeting the DSM - IV - TR symptom cluster criteria (to be counted as a symptom, minimum frequency = 1 and intensity = 2) and a total CAPS severity score of 45 or higher.14 Total CAPS symptom severity was the primary outcome.

Patients completed the Beck Depression Inventory II (BDI; score range, 0 - 63), 19 the trait (score range, 10 - 40) and anger expression (score range, 0 - 72) subscales of the State - Trait Anger Expression Inventory, 20 and the state subscale of the State - Trait Anxiety Inventory (score range, 20 - 80).21 Higher scores on all measures indicate greater symptom severity.

This finding probably reflects the higher levels of functional impairment and symptom severity in the group with COPD.

To be accepted into the trial, patients had to meet the following criteria: 18 to 65 years old; meeting diagnostic criteria for PTSD as determined by the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM - IV), 13 with PTSD being the main problem; scoring 20 or higher on the Posttraumatic Diagnostic Scale (PDS), 14 indicating moderate to severe symptom severity; and intervention starting within 6 months after the accident.

Also of interest was that preschoolers who had recovered from MDD still had higher MDD severity scores than controls with psychiatric disorders and no disorders, suggesting that a relatively high number of residual depressive symptoms were still manifest even during periods of recovery.

Specify current severity: Reactive Attachment Disorder is specified as severe when a child exhibits all symptoms of the disorder, with each symptom manifesting at relatively high levels.

For inclusion, adolescents had to score at least 32 on the APAI (score range 0 — 105, higher score indicates greater severity of symptoms), although 14 adolescents with scores between 28 and 31 were included to achieve target sample size, and report some difficulties in function on a gender - specific local function measure.

Specify current severity: Disinhibited Social Engagement Disorder is specified as severe when a child exhibits all symptoms of the disorder, with each symptom manifesting at relatively high levels.

Dysfunctional illness perception and illness behaviour associated with high somatic symptom severity and low quality of life in general hospital outpatients in China

Primary outcomes were the Posttraumatic Diagnostic Scale (PDS) 25,26 for PTSD symptoms and the Symptom Checklist Depression Scale (SCL - 20) for depressive symptoms.27 The PDS (17 items) assesses severity of PTSD symptoms over the prior 4 weeks with high internal consistency and test - retest reliability26; scores are summed and range from 0 to 51; scores of 10 or less are mild; 11 to 20, moderate; 21 to 35, moderate to severe; and at least 36, severe.

This gives a range of scores from 0 to 56 with higher scores representing higher depressive symptom severity.

Children with a higher level of pretreatment severity need greater decreases in symptoms to reach a subthreshold level of symptoms, therefore we also examined pre to posttreatment Reliable Change.

Our finding that the severity of depressive symptoms in our sample of patients with chronic pain was best correlated with a combination of heightened catastrophising, reduced sense of control over life, increased physical disability, lower pain self - efficacy beliefs, higher use of unhelpful self - management strategies, and lower perceived social support (after controlling for the possible effects of age, sex and duration of pain) is consistent with previous studies of patients with chronic pain.26 Interestingly, and somewhat contrary to clinical expectations, pain severity, pain - related distress, and fear of movement / (re) injury were not significantly associated with depressive symptom severity.

In multivariate models simultaneously including ODD diagnosis and CU levels, controlling by socioeconomic status, ethnicity, sex, severity of conduct disorder symptoms and other comorbidity, high CU scores were related to higher levels of aggression, withdrawn, externalizing and global symptomatology, functional impairment and higher probability of comorbid disorders and use of services.

In the present study, children with a higher level of pre-treatment symptom severity were less likely to have recovered at post-treatment.

Multiple hierarchical regression analyses showed that a higher level of QOL was predicted by higher levels of psychological flexibility and social connectedness, while controlling for symptom severity.

In the current study, the range of depressive symptom severity was restricted to moderate to high levels.

Given the high risk among young migraineurs of developing an insecure attachment style and anxiety symptoms, which are known to impact on children / adolescents migraine severity (14), special attention should be paid to maternal alexithymic traits and mother — child interaction.

It has been suggested that co-existent behaviour problems in the child predict parental stress to a higher extent than the severity of the autistic symptoms [27 — 29].

Paternal ADHD was found to be associated with the severity of children's ADHD symptoms and a trend for higher rates of CD for children in the paternal ADHD group.

Greater severity of maternal depressive symptoms independently predicted higher externalizing and internalizing scores at 24 months of age, after adjusting for maternal ethnicity and prenatal smoke exposure (Table 2).