Sentences with phrase «high throughput sequencing»

We currently operate several different types of Illumina sequencers and MinIon sequencers from Oxford Nanopore Technologies offering researchers access to cutting edge technology for high throughput sequencing for a wide range of applications.

His primary research interests are bioinformatics, computational biology, machine learning, and integrative analysis of high throughput sequencing data with an emphasis on regulatory genomics and epigenomics.

A large variety of methods is used including genetic, molecular and cytogenetic techniques, fluorescence in situ hybridisation and DNA «combing», as well as high throughput sequencing approaches such as DNA - seq for mutation landscape analyses, RNA - seq for transcriptome analyses and ChIP - seq mapping of chromatin - associated proteins and their genome - wide modulation in response to DNA damages.

Dr Gilchrist said: «This study suggests that we may improve significantly on the widely used analysis methods for determining gene expression levels from high throughput sequence data: absolute quantitation offers a much sounder basis for determining changes in gene expression level, a measure widely used to determine the consequence of genetic, chemical or physical disturbances in living systems.»

By leveraging the exponential improvements in the semiconductor industry (known as Moore's Law), the Ion Proton ™ Sequencing System provides an unprecedented level of scalability and flexibility to support a broad range of high throughput sequencing applications, ranging from human - scale genome to exome to transcriptome sequencing.

«Today, rapidly falling costs means that high throughput sequencing projects are revealing the entire gene sequences of ever more species, but the biological functions of most of these genes remain unknown,» said Dr. Olivier Lichtarge, professor of molecular and human genetics and director of the Computational and Integrative Biomedical Research Center at Baylor and senior author of the report.

My long - term research interests involve the analyzing high throughput sequencing data and the mathematical / computational modeling of biological systems.

Their function has been studied using a general and powerful method the lab developed called high throughput sequencing cross-linking immunoprecipitation, or HITS - CLIP, to create genome - wide maps of where RNA - binding proteins bind to RNA in living tissue.

Enter HITS - CLIP, a new approach that applies high throughput sequencing of RNAs isolated by crosslinking immunoprecipitation.

Michael Brudno's main research interest is the development of computational methods for the analysis of genomic datasets, especially High Throughput Sequencing data, including methods for the discovery of structural and copy - number polymorphisms and other genomic variation, identification of functional variants, and visualization of genomic data.

«Modern high throughput sequencing» was used for quantifying specific gut bacterial DNA signatures before and after consumption of nuts.

The CNAG offers researchers access to state - of - the - art methods for high throughput sequencing for a wide range of applications.

Robert Darnell uses high throughput sequencing and other techniques to investigate the proteins that regulate RNA and thereby affect gene expression.

Identification of disease causing mutations from high throughput sequencing is a critical but complex process due to the large amount of data generated by these technologies.

This is being done using viral inoculation experiments and high throughput sequencing of viral consortia from several coral taxa, life stages, and physiological states of corals.

He is also interested in the large - scale infrastructure required for modern bioinformatics including storage and access methods for high throughput sequencing data.

His focus is on developing innovative solutions for low cost and high throughput sequencing for various biological problems.

While there are techniques to identify known viruses, such as high throughput sequencing or high density microarrays, identifying truly novel virions could pose a problem, the authors write.

High throughput sequencing has accelerated the determination of genome sequences for thousands of human infectious disease pathogens and dozens of their vectors.

This ambitious project involves the screening of breast cancer patient T cells for antigen specifically and reactivity, high throughput sequencing, and bioinformatics.

High throughput sequencing is offered on a fee - for - service basis in the adjacent Genome Building.

In this application, we propose to characterize haplotypes, in over 1200 dogs from at least 50 breeds using a high throughput sequencing strategy.

Here, we present the first application of high throughput sequencing (HTS) of whole mitochondrial genomes (mitogenomes) to evaluate the phylogeographic patterns of differentiation between island and mainland gray fox populations.