Sentences with phrase «higher cytokine release»

In ZUMA - 1, 12 % of the patients had a grade 3 or higher cytokine release syndrome and that is essentially a patient requiring mechanical ventilation or needing treatment with a high - dose vasopressor.

Not exact matches

CAR - T treatments, including competing products from Novartis rivals Kite Pharma and Juno Therapeutics, come with the risk of potentially deadly side effects such as cytokine - release syndrome (CRS), in which a glut of T - cell - assisting cytokines can cause high fever, low blood pressure, and problems with lung oxygenation.

His lab differentiates iPSCs from autistic patients into neurons and glial cells, which they suspect may be releasing cytokines at levels higher than normal in autistic patients.

In the June issue of the journal Vaccine, Christopher Blyth at the University of Western Australia and colleagues found that Fluvax (but not other flu vaccines) triggered the release of high levels of cytokines in blood cells isolated from the children who had febrile seizures.

Cytokine release syndrome occurs when many cytokines get released into the serum upon CAR T - cell injection; patients can get high fevers and sometimes hypertension, and occasionally there is a need for mechanical ventilation or administration of vasopressors, but that is rare.

Researchers have investigated the effects of refined sugars on cognitive function, and conclude that «Special care in food selection at meals should be exercised by those with type 2 diabetes since ingestion of rapidly absorbed, high — glycemic index carbohydrate foods further impairs medial temporal lobe function, with food - induced increases in oxidative stress and cytokine release likely explaining the association between food ingestion and reduction in cognitive function in those with type 2 diabetes (1).»