Sentences with phrase «higher disease burden»

«Patients with persistent VPC asthma demonstrated higher disease burden, compromised lung function, and higher total and specific immunoglobin E levels than patients with non-persistent VPC asthma,» Haselkorn said.

This candidate vaccine has the potential to have a significant impact on public health in view of the high disease burden in endemic countries.»

T gondii is an important zoonosis with a high disease burden in humans.

«The high disease burden, particularly amongst young and elderly populations in poor to middle income countries, could potentially be addressed by further investment in research,» says Dr Stuart Clarke from the University of Southampton's Faculty of Medicine, who is leading the study.

Access to improved water sources have reduced disease incidence in parts of the world but the use of efficacious vaccines is seen as an important public health tool for countries with a high disease burden.

Not exact matches

«Patients with the highest burden of chronic disease typically have the greatest transportation barriers,» he explained.

Not breastfeeding not only leads to a greater burden of disease for both mother and child, but also to high economic costs, which have to be paid for by society.

In addition to disease burden, epidemics and pandemics impose high economic costs on communities, industries, gross domestic products, and development donors.

The resulting higher viral burden in the patients causes more severe disease symptoms, or even death.

«This may be referred to as the «pertussis paradox»: an increasingly large disease burden, despite consistently high vaccination coverage,» he said.

African populations harbour the greatest genetic diversity and have the highest per capita health burden, yet they are rarely included in large genome studies of disease association.

«After careful examination of the burden of disease among women aged 40 to 54 years, the guideline development group (GDG) concluded that the lesser, but not insignificant, burden of disease for women aged 40 to 44 years and the higher cumulative risk of adverse outcomes no longer warranted a direct recommendation to begin screening at age 40 years.»

«Higher health care cost burden of musculoskeletal conditions compared to other diseases.»

«The rapid shifts in disease burden place poor people in low - and middle - income countries at high risk of not having access to appropriate services and incurring payments for health care that push them deeper into poverty,» said Timothy Evans, Director of Health, Nutrition and Population at the World Bank Group.

While death rates from the acute phase of cardiovascular events have decreased, the disease burden remains high in the increasing number of survivors, which is especially important for those affected at a young age.

Preliminary findings from PREVAIL III, a study of Ebola virus disease (EVD) survivors being conducted in Liberia, indicate that both Ebola survivors and their close contacts have a high burden of illness.

Partly based on these findings, the World Health Organization is recommending that this vaccine be used only in areas where there is a known high burden of disease.

Although CRC affects all racial and ethnic groups, African Americans carry an excessive burden of disease with the highest overall incidence, highest incidence of advanced stage at presentation, highest mortality, and lowest survival rates compared to any other ethnic or racial group.

Chronically - ill cancer patients have different exercise limitations than their healthy counterparts and other concurrent diseases and high symptom burden add challenges in how best to study and implement physical activity programs in lung cancer patients.

«It could be due to the higher burden of illnesses that increase risk of heart disease, like hypertension and diabetes.

The ENCODE project that tries to make sense of the flood of human genetic information and the CERN high - energy physics lab are examples, he told the meeting, «and the global burden of disease is in that category.

«These families are also burdened with higher rates of asthma and other diseases linked with environmental contaminants.

«Existing treatment options for preeclampsia and research into the disease have been limited despite the scale of the disease burden and its high growth rate.

The majority of research investment comes from high - income countries, whereas the highest burden of infectious disease is in the developing world.

Gut microbiota varies by opioid use, circulating leptin and oxytocin in African American men with diabetes and high burden of chronic disease — Elena Barengolts — PLOS One

This Vascular Biology COBRE will be first of its kind in Rhode Island, a state with a high burden of both heart and lung disease.

Lewy bodies (LB) and other intracellular α - synuclein (AS) aggregates accumulate in the aging nervous system, and a high burden of such aggregates are hallmark neuropathological signs of Parkinson's disease (PD), Lewy body dementia (LBD), multiple systems atrophy (MSA), and other synucleinopathies.

Its characteristically low mutational burden, high copy number and structural variants, and unique driver mutation prevalence are important in helping us understand the natural history of the disease and its response to various therapies.

The Health and Retirement Study consists of older volunteers sampled from urban and rural areas across the U.S., while the Southern Community Cohort Study focuses on African Americans in the South, particularly areas that have a disproportionately high burden of disease.

Major problems in high TB disease burden countries are human and environmental factors that contribute to a weakened immune system and can increase susceptibility to Mtb infection, recurrence of latent infection and high morbidity and mortality.

World health experts have concluded with «very high confidence» that climate change already contributes to the global burden of disease and premature death [26].

The ST313 pathovar of Salmonella enterica serovar Typhimurium contributes to a high burden of invasive disease among African infants and HIV - infected adults.

Determining the true burden of typhoidal Salmonellae infections is hindered by lack of population - based studies and adequate laboratory diagnostics.The Strategic Typhoid alliance across Africa and Asia study takes a systematic approach to measuring the age - stratified burden of clinical and subclinical disease caused by typhoidal Salmonellae infections at three high - incidence urban sites in Africa and Asia.

An early and leading priority to do this is to strengthen AMR surveillance, particularly in low - income countries where the burden of infectious diseases is highest and where data are most limited.

In 1990, most years of healthy life were lost reportedly to undernutrition, such as diarrheal diseases in malnourished children, but now the greatest disease burden may be attributed to high blood pressure, a disease of overnutrition.

Farm workers have higher rates of many cancers, and increasing numbers of studies are starting to link a higher body burden of pesticides (from all sources) with Parkinson's disease.

Simply put, most people suffering from chronic health conditions are dealing with a high toxic burden that is overwhelming the body's natural defenses and triggering symptoms associated with Alzheimer's disease, cancer and cardiovascular issues.

The association between PM2.5 exposure and increased dementia risk suggests that the global burden of disease attributable to PM2.5 pollution has been underestimated, especially in regions with large populations exposed to high ambient PM2.5.

Indeed studies have empirically determined a large depletion in genetic diversity in some pedigree dogs breeds [1 — 3], and many breeds do suffer a high burden of genetic disease [4].

Many breeds face significant welfare problems due to a high burden of inherited disease [4] and extreme conformation [14], for which a lasting and widespread improvement can only be achieved via selection.

The program also ensures the human parents of cats like Sonic, a green eyed beauty, who suffers from a severe heart murmur and inflammatory bowel disease, and Brando and Cyrus aka Howard and Sirius, brothers who suffer from a myriad of serious issues, never have to worry about finding a trustworthy veterinarian or the burden of sky high medical bills.

• increases in malnutrition and consequent disorders, with implications for child growth and development; • increased deaths, disease and injury due to heat waves, floods, storms, fires and droughts; • the increased burden of diarrheal disease; • the increased frequency of cardio - respiratory diseases due to higher concentrations of ground - level ozone related to climate change; and, • the altered spatial distribution of some infectious disease vectors.

Patz says in the press release that you link to that «Our high consumption of energy is putting a huge disease burden on places that are quite remote from us.»

Older people are at much higher risk of dying during extreme heat events.136, 50,241,233 Pre-existing health conditions also make older adults susceptible to cardiac and respiratory impacts of air pollution25 and to more severe consequences from infectious diseases; 257 limited mobility among older adults can also increase flood - related health risks.258 Limited resources and an already high burden of chronic health conditions, including heart disease, obesity, and diabetes, will place the poor at higher risk of health impacts from climate change than higher income groups.25, 50 Potential increases in food cost and limited availability of some foods will exacerbate current dietary inequalities and have significant health ramifications for the poorer segments of our population (Ch.

Other effects include an altered burden of water - borne diseases; an increased frequency of cardio - respiratory illness due to higher concentrations of ground level ozone, and the movement of some infectious disease carriers into new regions.

* 20 to 30 % of plant and animal species likely to be at increased risk of extinction * many millions more people than today projected to experience floods every year due to sea level rise * increases in malnutrition; increased deaths, diseases and injury due to extreme weather events; increased burden of diarrhoeal diseases; increased frequency of cardio - respiratory diseases due to higher concentrations of ground - level ozone in urban areas * hundreds of millions of people exposed to increased water stress

«increases in malnutrition; increased deaths, diseases and injury due to extreme weather events; increased burden of diarrhoeal diseases; increased frequency of cardio - respiratory diseases due to higher concentrations of ground - level ozone in urban areas»

World health experts have concluded with «very high confidence» that climate change already contributes to the global burden of disease and premature death [26].

46) The IPCC alleges that «climate change currently contributes to the global burden of disease and premature deaths» but the evidence shows that higher temperatures and rising CO2 levels has helped global populations

Programs can be developed to modify sleep in an attempt to reduce the health burden on elderly populations, who are already at higher risk of disease.