Sentences with phrase «higher efficacy in»

Similarly, studies of oral PrEP have found much higher efficacy in highly adherent participants.

The vaccine's higher efficacy in older children is much more promising, he says.

Our results demonstrating Gleevec's high efficacy in CML tell us that in applying the drug to other cancers, we need to diagnose and treat patients earlier in the disease course.

Not exact matches

Deutsche Bank shares trading in Frankfurt were down more than 4 % on Monday, and credit - default swaps on the bank spiked to their highest level since 2012, when the entire efficacy of the eurozone was in doubt.

This webinar follows up on iAcquire's 2011 Quantifying Outreach study wherein they analyzed 300,000 outreach emails to determine what techniques yield the highest efficacy for outreach in link building.

Thus we must assign the mode of causal efficacy to the fundamental constitution of an occasion so that in germ this mode belongs even to organisms of the lowest grade; while the mode of presentational immediacy requires the more sophistical activity of the later states of process, so as to belong only to organisms of a relatively high grade.

Rather, it is a projection by a percipient subject onto a (fictitious) contemporaneous spatiotemporal manifold of certain highly refined and analyzed features of entities directly (but more vaguely and dimly) encountered in the percipient's immediate past through the mode of causal efficacy.8 The important distinction between true perception — what we might now in Rortyan jargon call nonmentalistic «unanalyzed raw feels» — and this second - order symbolic projection of select percepta characteristic only of higher - order conscious organisms is somewhat blurred by terming both equally «modes of perception.»

Ford, by contrast, has focused on a genetic analysis, similar in impact to the introduction of German «higher criticism,» in which we are to recognize early or preliminary formulations, superseded by later revisions and insertions in the text; forcing choices among alternative and incompatible doctrines, and producing a theory of Whitehead's own historical development of his «final» ideas or positions (in which, for example, concrescence gradually supersedes transition, and the power of causal efficacy is reduced to the status of the past as material cause, with the future or «final» cause dominating the process of concrescence).

We must assign the mode of causal efficacy to the fundamental constitution of an occasion so that in germ this mode belongs even to organisms of the lowest grade; while the mode of presentational immediacy requires the more sophistical activity of the latter stages of process, so as to belong only to organisms of a relatively high grade (PR 261).

Other surveys have documented high levels of interest and involvement in prayer, a high degree of belief in the efficacy of prayer, and a strong tendency to regard prayer as actual communication with God.

Throughout the ages, men and women of higher knowledge have been advancing the well - being of themselves and others in marvelous ways, thus proving the efficacy of spiritualized consciousness to help human existence.

All of our products are manufactured with the highest quality, efficacy, and care in all of our GMP - compliant facilities.

We have tested the efficacy of combining higher protein main meals with breakfast and lunch meal replacements in the form of shakes in the early stages of weight loss.

As manufacturers of dietary supplements continue to extend the utilization of nutraceutical excipients in improving the efficacy of their products, several market players are expected to offer excipients with higher stabilization properties for controlling a range of bioactive ingredients.

A recent analysis of the Longitudinal Study of Australian Children (LSAC) found that, in fathers, a higher parenting self - efficacy score was related to lower work - family strain; and a key mechanism by which fathers» work / family strain was decreased was by their doing more than they regarded as their «fair share» of child rearing tasks.

• Assumptions about different cultural groups and how they impact breastfeeding support • Shoshone and Arapaho tribal breastfeeding traditions shared through oral folklore • Barriers to decreasing health disparities in infant mortality for African Americans • Effects of inflammation and trauma on health disparities that result in higher rates of infant mortality among minority populations • Barriers to breastfeeding experienced by Black mothers and how lactation consultants can support them more effectively • Social support and breastfeeding self - efficacy among Black mothers • Decreasing pregnancy, birth, and lactation health disparities in the urban core • Positive changes in breastfeeding rates within the African American community • Grassroots breastfeeding organizations serving African American mothers

There also is additional independent research that underscores Heads Up Football's efficacy in reducing concussions at the high school level:

BY NATHAN RILEY Outraged that Mayor Bill de Blasio continues to sit on a city health department study into the efficacy of establishing safe places for drug users to pursue their high — facilities that are in place all over Europe with proven track records of reducing fatal overdoses — protestors sat down in the middle of Broadway across from City Hall bringing downtown traffic to a halt.

Liposomes, < 200 nm phospholipid vesicles, are longer retained in blood circulation and accumulate at pathological sites (tumours or inflamed tissues), leading to higher efficacy and lower systemic toxicity compared to the free drugs they encapsulate.

Although new synthetic drugs are closely evaluated for high specificity, high efficacy, low toxicity, and good pharmacokinetics, little attention is paid to the possibility that the chemically synthesized drugs may eventually be discharged from the human body into the environment in their original and / or metabolized forms.

«Climbers who rated as high in self - efficacy engaged in riskier climbs — they do more climbing, too,» Jones says.

In our case, we wanted items that could detect both low and high self - efficacy.

This led to two large clinical trials carried out by the Mayo Clinic in the late 1970s and mid-1980s (2, 3), which demonstrated that oral administration of a high dose of vitamin C had no efficacy as a cancer therapeutic.

The researchers also show how this works: sharing power leads to higher role breadth self - efficacy in subordinates, which in turn encourages their proactive behavior.

The authors say: «The excellent efficacy of DP for the treatment of malaria in multiple countries and for chemoprevention in our high transmission area suggest that this regimen will offer benefit in many regions in need of improved control measures.»

The research additionally shows that the mediating effect of role breadth self - efficacy is stronger when employees have high trust in their leader's competence.

KEYNOTE - 024 investigated the efficacy of pembrolizumab compared to standard of care with platinum - based chemotherapy in untreated patients with advanced NSCLC and high PD - L1 expression (defined as expression in at least 50 % of tumour cells).

«Our population in this trial also had a high response rate in the control group, so further studies are needed in broader populations to assess the efficacy of buprenorphine implants versus sublingual buprenorphine in other settings.»

Because high stress levels can cut into life - span and reproduction, at least in laboratory animals, Wasser says the results — which he emphasizes are preliminary — raise some questions about the efficacy of federal regulations designed to protect the owl.

During the past year alone, concerns about oversight of high - containment laboratories; vetting of personnel (personnel reliability); the efficacy of security measures in place for the select agent program; medical countermeasure research, development and distribution; bioterrorism and pandemic influenza preparedness; misuse of beneficial biological research and technologies; and microbial forensics have generated several policy evaluations and prompted the development of policy recommendations and legislation.

«In the tumor sample from a patient with high NRP - 1 expression, there was a significant improvement in the efficacy of the nanoparticle to induce tumor shrinkage,» said NeIn the tumor sample from a patient with high NRP - 1 expression, there was a significant improvement in the efficacy of the nanoparticle to induce tumor shrinkage,» said Nein the efficacy of the nanoparticle to induce tumor shrinkage,» said Nel.

«We report much higher therapeutic efficacy in preclinical brain tumor models using the combination of both therapies, leading to an increase in median survival,» Lowenstein says.

Many teachers in top - achieving schools with high levels of collective efficacy talked about how they used social persuasion to enforce norms of high expectations for student success.

The standard pharmaceutical development path for products that target pathogens moves slowly from studying safety, dosing, and biological responses in hundreds of people to an expensive efficacy trial with thousands of participants at high risk of becoming naturally infected.

Schools in which teachers showed high levels of collective efficacy had a 50 percent reduction in the academic disadvantage experienced by black students, compared to schools where teachers had average levels, the study showed.

Results also showed that when employees have high task self - efficacy but they do not perceive themselves as able to manage negative emotions in stressful and conflictual situations, understand others» needs and mood, or speak up for their rights and ideas, they undoubtedly perform well in their job but they «pay the price» in terms of well - being.

Given that the investigators have previously shown the influence of the host molecular clock on the gut microbiota, they will also ask if taking this NSAID at different times of day might lead to higher efficacy and less side effects in animal models and eventually in humans.

The current study — conducted in three neighborhoods of Merida, Mexico — measured the efficacy of indoor residual spraying against adult Aedes aegypti mosquitoes in houses treated with either deltamethrin (to which the local mosquitoes expressed a high degree of resistance) or bendiocarb (another insecticide to which the mosquitoes were fully susceptible), as compared to untreated control houses.

Starting from the age of four to seven months, half of the participants who are at high risk for the disease will be given oral insulin daily in the form of a powder, and half will be given an inactive substance (which is important in order to assess the efficacy of the treatment).

In the RV144 vaccine trial, led by the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research, the efficacy at 3.5 - years was 31.2 %; however, a higher early effect (60 %) was seen at 12 months.

In animal models, E1 - deleted human adenoviral recombinants of the serotype 5 (AdHu5) have shown high efficacy as vaccine carriers.

The efficacy of the best vaccines was very high in mice, providing complete protection with a single dose.

EOS100850 promotes anti-tumor efficacy in mouse tumor models in combination with several immune - checkpoint inhibitors, retains high potency in the presence of elevated intra-tumoral adenosine concentrations, and is non-brain penetrant.

The funding will help support our current clinical trial evaluating the safety and efficacy of ViaCyte's PEC - Direct product candidate, which is in development as a potential cure for patients with high - risk type 1 diabetes.

Vitamin B3 is found in food and supplements are available in stores, but safety in high doses and efficacy in human glaucoma patients needs to be proven.

The combination of pomalidomide plus low - dose dexamethasone showed efficacy with high rates of disease control in relapsed or refractory multiple myeloma patients with severe renal impairment, according to the results of a phase II study.

The Center for Predictive Medicine recognizes the challenges of translational research such as in designing and implementing high - throughput screens and assessing small molecules and potential vaccines for their efficacy in small animal models of disease.

Thailand Clinical Trials Development Trial MHRP, in collaboration with the P5, is planning an efficacy trial in a high - risk population of men who have sex with men (MSM) to hopefully improve upon the RV144 result and extend its relevance to at - risk populations to achieve the greatest public health impact.

But, he notes that it will be necessary to perform well - designed clinical trials that test the safety and efficacy of high - grade NMN in humans before making the leap to using NMN (or perhaps its analogs) as pharmacotherapeutic agents.

He also oversaw the licensure, under accelerated approval, of a new high - dose formulation of an influenza vaccine, which demonstrated superior efficacy to conventional vaccines in clinical trials.