Among the Dunedin study participants who developed asthma in childhood, those with
higher genetic risk scores were also more likely to suffer with persistent asthma into adulthood.
Across all three prospective studies,
a higher genetic risk score significantly increased the incidence of coronary events — as much as 90 percent in those at highest risk.
Within each genetic risk category, the presence of lifestyle factors significantly altered the risk of coronary events to such an extent that following a favorable lifestyle could reduce the incidence of coronary events by 50 percent in those with
the highest genetic risk scores.
Not exact matches
The researchers found that, when the «
genetic risk score» was used with the GFRC, the correct classification of individuals as
high or low fracture
risk was increased by 12 % over and above that of the traditional clinical
risk factors, which together correctly classify up to 80 % of the studied individuals into
high and low
risk categories.
The team found that
genetic variants that contribute to
higher scores on the Eyes Test also increase the
risk for anorexia, but not autism.
We predicted that MP's behavioral effects in marijuana abusers would be attenuated, consistent with preclinical findings (30), and that decreased DA reactivity in ventral striatum would be associated with
higher scores in negative emotionality (neuroticism), which mediates
genetic risk for marijuana dependence (31), and with addiction severity.
The researchers examined the relationship between a
risk score based on multiple
genetic differences and early - onset heart disease and found that the polygenic
risk score predicted a
high risk for early - onset disease in one in 53 people at the same level as FH does.
Anette - Gabriele Ziegler and colleagues report their novel
genetic risk score for identifying infants with a
high risk of developing type 1 diabetes.