Sentences with phrase «higher plasma concentrations»

Anxious dogs had significantly higher plasma concentrations of dopamine and serotonin compared with controls [93].

* Clinical research shows that Meriva supplementation results in higher plasma concentrations of curcumin from a much smaller amount than with ordinary curcumin.

Consumption of PHVOs was associated with higher plasma concentrations of sICAM - 1, either before (percentage difference between top and bottom quintiles in crude model: 28 %; P for trend: < 0.01) or after adjustment for confounders (percentage difference between top and bottom quintiles in model 2: 22 %; P for trend: < 0.01)(Table 4).

After control for potential confounders, women in the highest quintile of PHVO intake had higher plasma concentrations of C - reactive protein (CRP; percentage difference from lowest quintile: 45 %; P for trend: < 0.01), tumor necrosis factor - α (TNF - α; 66 %; P for trend: < 0.01), interleukin - 6 (72 %; P for trend: < 0.05), and soluble intercellular adhesion molecule - 1 (sICAM - 1; 22 %; P for trend: < 0.01) than did women in the lowest quintile.

In fact, one double blind, placebo - controlled study found that after seven weeks of supplementing, creatine ethyl ester resulted in less creatine in the muscles and blood than regular monohydrate, plus it appears to lead to higher plasma concentrations of the byproduct creatinine.

Indeed, babies fed higher levels of breast milk show higher plasma concentration levels of DHA and AA in the brain cortex, cerebral grey and white matter, as well as a higher IQ up to 15 years of age compared to babies fed formula not containing LCPUFA.

«A higher plasma concentration of these proteins means that there has been greater damage of muscle fibres and, therefore, a greater probability of fatigue.

Not exact matches

The plasma concentration of pethidine in the infant is almost as high as that in the mother, reaching a maximum after 2 - 3 hours, after which the level falls slowly.

Soy fed infants have a phytoestrogen circulation that is 13,000 - 22,000 times higher than maternal plasma estrogen concentrations (Setchell, 1997).

On the other hand, breast - fed infants are consistently reported to have higher plasma cholesterol concentrations than formula - fed infants (22 — 24).

-- Hyperimmune globulin, prepared by purifying and concentrating plasma of immunized animals or previously infected humans with high titers (concentrations) of neutralizing antibody against Ebola virus, which have been shown to be protective in monkeys but are not currently available and would not be expected before mid-2015.

Concentrations of plasma proteins were between 5 and 20 times higher than levels found at 4 o'clock in the afternoon.

Mice fed high folic acid in the treatment group had higher concentrations of unmetabolized folic acid in blood plasma and higher folate concentrations in the spleen when compared to mice in the control group.

High salt intake increases plasma trimethylamine N - oxide (TMAO) concentration and produces gut dysbiosis in rats — Klaudia Bielinska — Nutrition

Osimertinib showed preclinical evidence of concentrations in mouse brain tissue 5 - to 25-fold higher than in plasma, [16] and has shown greater penetration of the BBB in mouse models than gefitinib, rociletinib, or afatinib.

The study found that that high concentration of antibodies that bind to V1 and V2 regions of the correlates, that keep changing, have reduction in infection rate by 43 per cent but high plasma IgA envelope indicated 54 per cent increase in the infection rate.

Indeed, high concentrations of fibrinogen in blood plasma appear to make erythrocytes aggregate together more.

Among the 50 trials, 30 were primary prevention trials (general populations, smokers and workers exposed to asbestos, patients with oesophageal dysplasia, male physicians, patients with non-melanoma skin cancer, postmenopausal women, patients undergoing chronic haemodialysis, patients with end stage renal disease, ambulatory elderly women with vitamin D insufficiency, patients with chronic renal failure, older people with femoral neck fractures, patients with diabetes mellitus, elderly women with a low serum 25 - hydroxyvitamin D concentration, health professionals, people with a high fasting plasma total homocysteine concentration, or kidney transplant recipients), and 20 were secondary prevention trials (patients with cardiovascular disease, coronary heart disease, acute myocardial infarction, unstable angina, transient ischaemic attack, stroke, angiographically proved coronary atherosclerosis, vascular disease, or aortic valve stenosis).

Furthermore, homozygosity for null mutations at CYP2F1 was found associated with higher plasma interleukin - 8 concentrations; and at either A3GALT2 or NRG4, with markedly reduced plasma insulin C - peptide concentrations; hence identifying novel phenotypic associations at these genes.

Researchers found that the high nitrate concentration in spinach (juiced in the study) increases the plasma nitrate and nitrate concentrations in the body, which effectively lowers blood pressure.

Weigle, DS et al. 2005 A high - protein diet induces sustained reductions in appetite, ad - libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations.

«A High Fasting Plasma Insulin Concentration Predicts Type 2 Diabetes Independent of Insulin Resistance: Evidence for a Pathogenic Role of Relative Hyperinsulinemia,» Diabetes, 49 (12), 2094 - 2101.

David S Weigle, Patricia A Breen, Colleen C Matthys, Holly S Callahan, Kaatje E Meeuws, Verna R Burden, Jonathan Q Purnell; A high - protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations, The American Journal of Clinical Nutrition, Volume 82, Issue 1, 1 July 2005, Pages 41 — 48, https://doi.org/10.1093/ajcn/82.1.41

The isocaloric high - protein diet led to no significant change in nadir plasma concentrations, peak plasma concentrations, or AUC values for the 24 - h leptin profiles obtained during CRC2 compared with those obtained during visit CRC1.

The vegetable oil diet in this study provided ten times more vitamin E than the control diet, and after consuming these diets for two to three years the plasma vitamin E concentrations of the subjects consuming the vegetable oil diet were twice as high as those consuming the control diet.

Patients with advanced AD show higher plasma but lower CSF insulin concentrations than healthy controls.40 Clearly, then, the lower concentration of insulin in the brain is not a result of reduced circulating levels in the blood.

Platelet - rich plasma is obtained via a process called centrifugation that removes red and white blood cells from a blood sample while leaving behind a high concentration of platelets in the plasma.

The drop in blood pressure was associated with the highest blood plasma concentration of phenolic compounds, particularly vanillic acid and protocatechuic acid.

We found that higher intakes of non-HVOs are independently associated with lower plasma concentrations of some inflammatory markers.

In conclusion, our findings indicated that higher intakes of PHVOs were associated with elevated concentrations of inflammatory biomarkers, whereas higher intakes of non-HVOs were associated with lower plasma concentrations of these biomarkers.

Since... infant formulas contain very little cholesterol (10 to 30 mg / L)(Huisman et al., 1996; Wong et al., 1993), it is not surprising that plasma cholesterol concentrations are higher in infants fed human milk than in formula - fed infants.

Lithium is accumulated at highly concentrated levels in the thyroid gland (at 3 to 4-fold higher concentrations as compared to its plasma levels).

Disproportionately high plasma insulin concentration in hypertensive patients was first reported in the scientific literature more than fifty years ago.

You need to have a high plasma glucose concentration and spiked serum insulin levels to drive maximum cellular creatine delivery.

Consuming a high glycemic food within 45 minutes after exercise elevates plasma glucose concentrations and facilitates muscle glycogen replenishment.

This was a retrospective study of TPO - Ab concentrations in 36 women and 2 men (mean age 51 + / - 16 years; range 19 - 81 years) with Hashimoto's thyroiditis as defined by the following criteria: elevated plasma TPO - Ab and typical hypoechogenicity of the thyroid in high - resolution sonography at first presentation or during follow - up and low pertechnetate uptake in thyroid scintigraphy.

«Because the human gut is host to 100 trillion commensal organisms, which together contribute to an enteric reservoir of 1 g LPS (8), we hypothesized that most of the circulating endotoxin may derive from the gut and that a small amount of commensally derived] LPS maycotransit with dietary fat from the gut after a high - fat meal, which thereby increases plasma endotoxin concentrations postprandially»

High - monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations.

Diets high in protein or saturated fat do not affect insulin sensitivity or plasma concentrations of lipids and lipoproteins in overweight and obese adults.

It was found that higher physical workloads correlated with larger decreases in plasma ketone concentration (n = 8), consistent with their oxidation as respiratory fuels.

However, the effects of dietary fiber on glycemic control were considered inconsequential.1 Furthermore, the expert panel of the ADA considered it difficult to achieve a high dietary intake of soluble fiber without consuming foods or supplements fortified with fiber.1 We therefore designed the present study to determine the effects on glycemic control and plasma lipid concentrations of increasing the intake of dietary fiber in patients with type 2 diabetes exclusively through the consumption of foods not fortified with fiber (unfortified foods) to a level beyond that recommended by the ADA.

Daily plasma glucose concentrations were 10 percent lower with the high - fiber diet than with the ADA diet (values for the area under the curve, 3743 ± 944 vs. 3365 ± 1003 mg ․ hour per deciliter [207.8 ± 52.4 vs. 186.8 ± 55.7 mmol ․ hour per liter]; P = 0.02), and plasma insulin concentrations were 12 percent lower (values for the area under the curve, 1107 ± 650 vs. 971 ± 491 μU ․ hour per milliliter [6642 ± 3900 vs. 5826 ± 2946 pmol ․ hour per liter]; P = 0.05)(Figure 1).

A high intake of dietary fiber, particularly of the soluble type, above the level recommended by the ADA, improves glycemic control, decreases hyperinsulinemia, and lowers plasma lipid concentrations in patients with type 2 diabetes.

Previous studies in normal subjects have reported no effects of the amount of dietary fiber on plasma triglyceride concentrations.42 In our study, the decrease in plasma triglyceride and VLDL cholesterol concentrations during the high - fiber diet could have been due to the improvement in glycemic control.

The mean plasma glucose concentration was lower (by 13 mg per deciliter [0.7 mmol per liter], or 8.9 percent) when patients completed the high - fiber diet than when they completed the ADA diet (P = 0.04), and mean daily urinary glucose excretion was 1.3 g lower (P = 0.008).

As compared with the ADA diet, the high - fiber diet resulted in a lower fasting plasma total cholesterol concentration (by 6.7 percent, P = 0.02), a lower plasma triglyceride concentration (by 10.2 percent, P = 0.02), and a lower plasma VLDL cholesterol concentration (by 12.5 percent, P = 0.01)(Table 4).

During the sixth week of the high - fiber diet, as compared with the sixth week of the ADA diet, mean daily preprandial plasma glucose concentrations were 13 mg per deciliter (0.7 mmol per liter) lower (95 percent confidence interval, 1 to 24 mg per deciliter [0.1 to 1.3 mmol per liter]; P = 0.04) and mean daily urinary glucose excretion was 1.3 g lower (median difference, 0.23 g; 95 percent confidence interval, 0.03 to 1.83; P = 0.008).

The fasting plasma LDL cholesterol concentration was 6.3 percent lower with the high - fiber diet (P = 0.11).

The people with the highest blood concentrations of plasma vitamin C were found to have the lowest levels of cognitive impairment.

The high - fiber diet also lowered the area under the curve for 24 - hour plasma glucose and insulin concentrations, which were measured every two hours, by 10 percent (P = 0.02) and 12 percent (P = 0.05), respectively.