In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with
higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia.
+ / + - Homozygotes for this variant allele in the CTH gene had significantly
higher plasma homocysteine levels than other genotypes in a cohort of 496 Caucasian individuals.
Not exact matches
Patients with hypothyroidism have significantly
higher plasma levels of
homocysteine (16).
In addition, no causal relationship has been established between
high total
plasma homocysteine levels (tHCYs) and cardiovascular disease43.