Some breeds have
higher risk factors including:
Not exact matches
Important
factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook
include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy,
including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts,
including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft,
including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein,
including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals,
including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the
risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt,
including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to
higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue,
including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the
risks of doing business internationally,
including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Actual results,
including with respect to our targets and prospects, could differ materially due to a number of
factors,
including the
risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the
risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the
risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the
risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in
higher production costs and lower margins; our ability to lower costs; the
risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity,
including bringing on additional capacity on a timely basis to meet customer demand; the
risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the
risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix;
risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the
risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the
risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs,
including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments;
risks resulting from the concentration of our business among few customers,
including the
risk that customers may reduce or cancel orders or fail to honor purchase commitments; the
risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the
risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the
risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the
risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the
risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired;
risks relating to confidential information theft or misuse,
including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products
risks related to our multi-year warranty periods for LED lighting products;
risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products;
risks associated with ongoing litigation; and other
factors discussed in our filings with the Securities and Exchange Commission (SEC),
including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.
Factors that could cause actual results to differ
include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of
high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; delays in the completion of project sales; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other
risks as described in the Company's SEC filings,
including its annual report on Form 20 - F filed on April 27, 2017.
Factors that could cause actual results to differ
include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of
high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other
risks as described in the Company's SEC filings,
including its annual report on Form 20 - F filed on April 20, 2016.
Factors that could cause actual results to differ
include general business and economic conditions and the state of the solar industry; governmental support for the deployment of solar power; future available supplies of
high - purity silicon; demand for end - use products by consumers and inventory levels of such products in the supply chain; changes in demand from significant customers; changes in demand from major markets such as Japan, the U.S., India and China; changes in customer order patterns; changes in product mix; capacity utilization; level of competition; pricing pressure and declines in average selling prices; delays in new product introduction; delays in utility - scale project approval process; delays in utility - scale project construction; cancelation of utility - scale feed - in - tariff contracts in Japan; continued success in technological innovations and delivery of products with the features customers demand; shortage in supply of materials or capacity requirements; availability of financing; exchange rate fluctuations; litigation and other
risks as described in the Company's SEC filings,
including its annual report on Form 20 - F filed on April 27, 2017.
Factors that could cause actual results to differ materially from those expressed or implied in any forward - looking statements include, but are not limited to: changes in consumer discretionary spending; our eCommerce platform not producing the anticipated benefits within the expected time - frame or at all; the streamlining of the Company's vendor base and execution of the Company's new merchandising strategy not producing the anticipated benefits within the expected time - frame or at all; the amount that we invest in strategic transactions and the timing and success of those investments; the integration of strategic acquisitions being more difficult, time - consuming, or costly than expected; inventory turn; changes in the competitive market and competition amongst retailers; changes in consumer demand or shopping patterns and our ability to identify new trends and have the right trending products in our stores and on our website; changes in existing tax, labor and other laws and regulations, including those changing tax rates and imposing new taxes and surcharges; limitations on the availability of attractive retail store sites; omni - channel growth; unauthorized disclosure of sensitive or confidential customer information; risks relating to our private brand offerings and new retail concepts; disruptions with our eCommerce platform, including issues caused by high volumes of users or transactions, or our information systems; factors affecting our vendors, including supply chain and currency risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and risks associated with being a controlled c
Factors that could cause actual results to differ materially from those expressed or implied in any forward - looking statements
include, but are not limited to: changes in consumer discretionary spending; our eCommerce platform not producing the anticipated benefits within the expected time - frame or at all; the streamlining of the Company's vendor base and execution of the Company's new merchandising strategy not producing the anticipated benefits within the expected time - frame or at all; the amount that we invest in strategic transactions and the timing and success of those investments; the integration of strategic acquisitions being more difficult, time - consuming, or costly than expected; inventory turn; changes in the competitive market and competition amongst retailers; changes in consumer demand or shopping patterns and our ability to identify new trends and have the right trending products in our stores and on our website; changes in existing tax, labor and other laws and regulations,
including those changing tax rates and imposing new taxes and surcharges; limitations on the availability of attractive retail store sites; omni - channel growth; unauthorized disclosure of sensitive or confidential customer information;
risks relating to our private brand offerings and new retail concepts; disruptions with our eCommerce platform,
including issues caused by
high volumes of users or transactions, or our information systems;
factors affecting our vendors, including supply chain and currency risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and risks associated with being a controlled c
factors affecting our vendors,
including supply chain and currency
risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and
risks associated with being a controlled company.
These
risks and uncertainties
include food safety and food - borne illness concerns; litigation; unfavorable publicity; federal, state and local regulation of our business
including health care reform, labor and insurance costs; technology failures; failure to execute a business continuity plan following a disaster; health concerns
including virus outbreaks; the intensely competitive nature of the restaurant industry;
factors impacting our ability to drive sales growth; the impact of indebtedness we incurred in the RARE acquisition; our plans to expand our newer brands like Bahama Breeze and Seasons 52; our ability to successfully integrate Eddie V's restaurant operations; a lack of suitable new restaurant locations;
higher - than - anticipated costs to open, close or remodel restaurants; increased advertising and marketing costs; a failure to develop and recruit effective leaders; the price and availability of key food products and utilities; shortages or interruptions in the delivery of food and other products; volatility in the market value of derivatives; general macroeconomic
factors,
including unemployment and interest rates; disruptions in the financial markets;
risk of doing business with franchisees and vendors in foreign markets; failure to protect our service marks or other intellectual property; a possible impairment in the carrying value of our goodwill or other intangible assets; a failure of our internal controls over financial reporting or changes in accounting standards; and other
factors and uncertainties discussed from time to time in reports filed by Darden with the Securities and Exchange Commission.
High -
risk loan
factors, which are associated with
higher mortgage rates,
include a history of late or «slow» repayments to creditors; borrowing for a multi-unit home or a condominium; and, borrowing to finance a vacation home or an investment property.
Due to its fatty acid and
high dietary fiber content, chia seeds are considered in holistic medicine to be beneficial in reducing cardiovascular
risk factors including diabetes, hypercholesterolemia, hypertension and inflammation.
Risk factors include: 1) age (most people are diagnosed in their 20s - 30s), 2) race or ethnicity (Caucasians have the highest risk, but IBD can occur in any race; there's an even higher risk if you are of Ashkenazi Jewish descent), 3) family history (risk is higher if a close relative has the disease), 4) cigarette smoking (the most important controllable risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized count
Risk factors include: 1) age (most people are diagnosed in their 20s - 30s), 2) race or ethnicity (Caucasians have the
highest risk, but IBD can occur in any race; there's an even higher risk if you are of Ashkenazi Jewish descent), 3) family history (risk is higher if a close relative has the disease), 4) cigarette smoking (the most important controllable risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized count
risk, but IBD can occur in any race; there's an even
higher risk if you are of Ashkenazi Jewish descent), 3) family history (risk is higher if a close relative has the disease), 4) cigarette smoking (the most important controllable risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized count
risk if you are of Ashkenazi Jewish descent), 3) family history (
risk is higher if a close relative has the disease), 4) cigarette smoking (the most important controllable risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized count
risk is
higher if a close relative has the disease), 4) cigarette smoking (the most important controllable
risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized count
risk factor for developing CD), 5) nonsteroidal anti-inflammatory medications (
includes ibuprofen [Advil, Motrin IB, others], naproxen sodium [Aleve], diclofenac sodium [Voltaren], and others), and 6) where you live (you are more likely to develop IBD if you live in an industrialized country).
Common
risk factors include: smoking,
high blood pressure, diabetes,
high cholesterol levels, or being overweight / obese.
The main issues in Australia regarding homebirth centre around the
risks to the baby, with
higher perinatal mortality rates reported in some studies of homebirth [14, 15] however these studies have
included women with
risk factors (e.g., twins, medical complications), so it is difficult to draw conclusions about low -
risk women [14, 16].
Babies left to sleep on their stomachs while on very soft bedding areas are said to be at the
highest risk of SIDS of all.Various other external
factors also come into play,
including whether or not the parents of the baby smoke, if the baby was delivered prematurely and whether or not immediate post-natal care was sufficient, all of which can influence SIDS
risk.
There has been concern raised about a resurgence of vitamin D deficiency and rickets among infants and children, with reports emerging in the United States from Alaska, 1,2 Iowa, 3 Nevada, 4 California, 5 North Carolina, 6 Texas, 7 and mother - infant pairs in Boston, 8 among others.9 The prevalence of vitamin D deficiency in young children also appears to be
high in other countries,
including England, 10 Greece, 11 and Canada.12, 13 One study from China found a 65.3 % prevalence of vitamin D deficiency among 12 - to 24 - month - olds, but few cases (3.7 %) of radiographic or clinical rickets were noted.14 Previous studies suggest
risk factors to be dark skin pigmentation1,3 - 12 and breastfeeding without supplementation.1 - 7, 9,12,13 To date, reports have focused primarily on young infants compared with toddlers.
High risk factors for a food allergy
include:
There are several
factors that may put a pregnant woman at
higher risk of a preterm birth,
including a previous preterm birth, multiple pregnancies such as twins, triplets, etc, some chronic medical conditions such as
high blood pressure, diabetes and infections.
Other
risk factors to increase the
risk of third and fourth degree tearing at second birth
include;
high birth weight, forceps delivery and the presence of shoulder dystocia.
While father absence has been associated with a host of negative children's outcomes,
including increased
risk of dropping out of school and lower educational attainment, poorer physical and mental health, and behavioural problems,36 - 40
higher levels of involvement by nonresident fathers may assuage the negative effects of father absence on children's outcomes.41, 42 Quality of the parents» relationship before divorce, or of the pre-divorce father / child relationship, can also be an important
factor: children fare worse following divorce when pre-divorce relationships were good and fare better when pre-divorce relationships were poor, 43,44 suggesting children are sometimes better off without a father if the father's relationship to the child or the mother was not good.
Other
risk factors include having had gestational diabetes with a previous pregnancy, having a large baby in a previous pregnancy and having consistent
high glucose levels prior to pregnancy (usually considered pre-diabetic).
Some
risks factors for pregnancy - related hypertension
include being overweight, having hypertension before pregnancy, pregnant with multiples, having a chronic illness, and / or poor diet (
high salt and
high fat diets).
After adjusting to account for other CRC
risk factors,
including other dietary components, the researchers narrowed in on
high fish and fruit and low soft drinks as the best combo for reduced odds of advanced colorectal polyps.
«Skipping breakfast may lead to one or more
risk factors,
including obesity,
high blood pressure,
high cholesterol and diabetes, which may in turn lead to a heart attack over time,» said Leah E. Cahill, Ph.D., study lead author and Postdoctoral Research Fellow in the Department of Nutrition at Harvard School of Public Health in Boston, Mass..
There, she studied the contribution to global death tolls, and their trajectories over time, of cardiometabolic
risk factors (
including high blood pressure and obesity) and undernutrition.
The study
included 3,731 obese adults and overweight adults who had at least one other
risk factor for heart disease, such as prediabetes,
high blood pressure or
high cholesterol.
Treatment with the diabetes drug liraglutide, in combination with diet and exercise, led to a significant reduction in weight and improved a number of cardiovascular
risk factors,
including high blood pressure and
high cholesterol, according to a multicenter study.
They found a
higher prevalence of
risk factors for poor outcomes in black children that
include ventilator use, oxygen support, wound infections, transfusions and neonatal status.
According to the Centers for Disease Control and Prevention, the most effective way to prevent aortic aneurysms is reducing
risk factors including quitting smoking and controlling
high blood pressure and
high cholesterol.
After accounting for age, coronary calcium score and cardiovascular
risk factors including diabetes,
high blood pressure and
high cholesterol, women using hormone replacement therapy were overall 30 percent less likely to die than those not on hormone therapy.
Those whose parents made it to 85 scored
higher on a variety of
factors,
including a combined measure of heart health called the Framingham
risk score, which takes into account age, cholesterol, blood pressure, hypertension and cigarette smoking.
This difference was independent of other heart disease
risk factors including age, gender, family history, education level, body mass index, smoking habits, hypertension, diabetes and
high cholesterol, all of which the researchers adjusted for in their analysis.
Risk factors included diabetes,
high blood pressure,
high blood cholesterol and coronary artery disease.
These
risk factors raise the likelihood of developing heart and blood vessel diseases and conditions in adulthood,
including coronary artery disease, heart attacks, strokes,
high blood pressure, obesity and type 2 diabetes.
After adjusting for numerous possible confounding
factors,
including body mass index and alcohol use, the researchers found that women in the
highest quartile of GGT had nearly twice the
risk of subsequent gestational diabetes than those in the lowest quartile.
The known
risk factors the researchers focused on
included depression, lower education levels, physical inactivity,
high blood pressure, diabetes, obesity and smoking.
First, the surgeon or other user enters, into blank data fields, the planned surgical procedure and 19 patient - specific preoperative
risk factors,
including age, body mass index obtained from height and weight, smoking status, and health conditions such as
high blood pressure and diabetes.
After controlling for potential confounding
factors including childhood IQ, those in the lowest GPA quartile had a near five-fold
higher risk of suicide attempt than those in the
highest quartile.
«One explanation for the
high rate of risky opioid use among disability - entitled enrollees is the group of
risk factors linked with opioid misuse
including mood disorders, cognitive disability and back pain - related disorders,» Kuo said.
Future studies that
include more participants or that track women for a longer period could help illuminate the
factors that contribute to cardiovascular
risk among women with normal and
high blood pressure during pregnancy, researchers said.
Specific
risk factors for anorexia
include: being female, age (early - mid adolescence is the prime time for onset), perfectionism,
high parental conflict, highly demanding parents, and concerns about shape and weight (and subsequent dieting).
Other
risk factors for diabetes
included AHI during rapid eye movement sleep and measures of the physiologic consequences of OSA,
including oxygen desaturation, sleep deprivation and activation of the sympathetic nervous system, as indicated by a
higher mean heart rate during sleep.
In analyses adjusting for known
risk factors for diabetes,
including age, sex, body mass index, neck circumference, smoking, income status and comorbidities at baseline, patients with an AHI > 30 had a 30 %
higher risk of developing diabetes than those with an AHI < 5.
While many environmental
risk factors exist,
including high blood pressure and smoking, stroke
risk is also frequently inherited.
The researchers found that the association between DDT and
high blood pressure held after accounting for some
factors known to raise the
risk of hypertension,
including age, race, body mass and diabetes status.
«We believe some
factors contributing to the
higher risk may
include long - term exposure to poor living conditions and stressors in transition countries
including anxiety, racism, domestic or personal violence and major life events, such as a death in the family — to name a few,» said Dr. Wanigaratne.
Across states, significant variation has been described in the prevalence of CVD and cardiovascular health and
risk factors,
including hypertension, smoking,
high blood cholesterol, diabetes, overweight / obesity, physical inactivity, and limited consumption of vegetables and fruits.
The
risk factors, together known as metabolic syndrome,
include a large waistline,
high triglyceride (a blood fat) levels, low HDL (the «good» cholesterol) levels,
high blood pressure and
high blood sugar when fasting.
«Our findings indicate that sexual minorities living in communities with
higher levels of prejudice die sooner than sexual minorities living in low - prejudice communities, and that these effects are independent of established
risk factors for mortality,
including household income, education, gender, ethnicity, and age, as well as the average income and education level of residents in the communities where the respondents lived,» said Dr. Hatzenbuehler.
Maguen: «I do think military women are extremely resilient, but I think the differences in rates in the civilian literature actually have to do with a number of
factors,
including women having much
higher rates of interpersonal traumas, which we know put people at
high risk for PTSD.»
These
include a history of depression, alcohol, education, diet, and a cluster called vascular
risk factors because they affect the blood supply in the brain, such as stroke, heart disease,
high blood pressure,
high cholesterol, diabetes and obesity.