Researchers specifically investigated the genetic profiles for those at
highest risk for coronary heart disease and a heart rhythm disorder called atrial fibrillation, or AFib.
Not exact matches
Earlier studies have demonstrated that cocoa flavanol intake improves the elasticity of blood vessels and lowers blood pressure — but,
for the most part, these investigations have focused on
high -
risk individuals like smokers and people that have already been diagnosed with conditions like hypertension and
coronary heart disease.
The study also found distinct blood pressure patterns from ages 18 to 55 that reveal people at
high risk for calcification of
coronary arteries — a marker
for heart disease — by middle age.
Vitamin D deficiency is an independent
risk factor
for heart disease with lower levels of vitamin D being associated with a
higher presence and severity of
coronary artery
disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.
Although cholesterol is a key structural component of cell membranes and is vital
for the biosynthesis of certain hormones and vitamins,
high levels can lead to the formation of arterial plaques, which are a major
risk factor
for coronary heart disease.
Dr Nelson added: «We also examined whether the association we found between shorter height and
higher risk of
coronary heart disease could be explained by an effect of height on known
risk factors
for coronary heart disease like cholesterol,
high blood pressure, diabetes etc..
«While our findings do not have any immediate clinical implications, better and fuller understanding of the biological mechanisms that underlie the relationship between shorter height and
higher risk of
coronary heart disease may open up new ways
for its prevention and treatment.»
For example, compared to a 5ft 6inch tall person, a 5 foot tall person on average has a 32 %
higher risk of
coronary heart disease because of their relatively shorter stature.
In the April 13, 2007, issue of Science, the research team — led by James C. Lo, an MD, PhD student, in the laboratory of Yang - Xin Fu, MD, PhD, professor of pathology at the University of Chicago — suggest that an engineered protein could keep mice, and possibly humans, from developing
high cholesterol and triglyceride levels, a key
risk factor
for coronary heart disease.
deCODE MI ™ The deCODE MI ™ test detects two SNPs located on chromosome 9p21, discovered by deCODE and which various genome - wide association studies have confirmed as the
highest impact genetic
risk factor
for heart attack and
coronary artery
disease identified to date.
A
high excess relative
risk (in comparison with 20 cigarettes per day) was seen in 17 of 20 estimates (median 57 % all estimates; 49 %
for coronary heart disease and 62 %
for stroke, comparable to those from the meta - analyses).
Blood cholesterol is a
risk factor
for coronary artery
disease and
heart attack, so reducing your
risk of
high cholesterol is a worthy goal.
However,
high blood cholesterol levels are an important
risk factor
for coronary heart disease.
For example, one 2013 study published in the journal Circulation found that men who skipped breakfast had a significantly
higher risk of
coronary heart disease than men who ate breakfast.
«This systematic review and meta - regression analysis of 108 randomised controlled trials using lipid modifying interventions did not show an association between treatment mediated change in
high density lipoprotein cholesterol and
risk ratios
for coronary heart disease events,
coronary heart disease deaths, or total deaths whenever change in low density lipoprotein cholesterol was taken into account.
Moreover,
high blood pressure increases the
risk for a variety of cardiovascular
diseases, including stroke,
coronary artery
disease,
heart failure, and peripheral vascular
disease.
Those with
high triglyceride levels taking omega - 3s showed as much as a 16 percent reduction in
risk for coronary heart disease.
A diet
high in saturated fat is a
risk factor
for coronary artery
disease,
high blood pressure and
heart attacks.
The long - term consumption of a diet with a relatively
high GL (adjusted
for total energy) is associated with an increased
risk of type 2 diabetes and
coronary heart disease (9).
There are numerous tests that are shown to be more important markers of an increased
risk of
coronary artery
disease than cholesterol.There are many causes and
risk factors
for heart disease, including inflammation,
high cholesterol, low testosterone, low thyroid, low estrogen, hypertension,
high lipoprotein A, insulin resistance, diabetes, obesity,
high homocystine, nutritional deficiencies and excessive oxidation, to name a few.
A study in the journal Circulation found people with abnormally
high level of lipids, such as cholesterol, in their blood were able to significantly reduce their
risk factors
for coronary heart disease by snacking on whole almonds (those who snacked on whole - wheat muffins received no such benefit).6
Even if your 10 - year
risk score isn't
high, metabolic syndrome will increase your
risk for coronary heart disease over time.
Conclusions and Relevance A genetic predisposition to
higher waist - to - hip ratio adjusted
for body mass index was associated with increased
risk of type 2 diabetes and
coronary heart disease.
High content of mercury in hair may be a
risk factor
for acute
coronary events and CVD, CHD, and all - cause mortality in middle - aged eastern Finnish men.Virtanen JK, Voutilainen S, Rissanen TH, Mursu J, Tuomainen TP, Korhonen MJ, Valkonen VP, Seppanen K, Laukkanen JA, Salonen JT., Mercury, fish oils, and
risk of acute
coronary events and cardiovascular
disease,
coronary heart disease, and all - cause mortality in men in eastern Finland., Arterioscler Thromb Vasc Biol.
A genetic predisposition to
higher waist - to - hip ratio adjusted
for body mass index was associated with increased
risk of type 2 diabetes and
coronary heart disease.
If you have
high cholesterol, you are at increased
risk for stroke,
coronary heart disease (which can lead to a
heart attack) and other adverse medical conditions.
Early menarche remained linked to
higher risks of
coronary heart disease and deaths from cardiovascular
disease and cancer after the researchers accounted
for a number of other factors — such as age, BMI, smoking, exercise habits and education.
Between 31 % and 45 % of people with
coronary heart disease suffer from clinically significant depressive symptoms, and 15 % — 20 % of them meet criteria of major depressive disorder which is roughly threefold
higher than in the general population.13 It is now well established that depression is related to the incidence of CVD and is also an independent
risk factor
for cardiac morbidity and mortality.