Sentences with phrase «highly immunodeficient mice»
NSG ™ variants are the most highly immunodeficient mice and the models of choice for cancer xenograft modeling, stem cell...
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However, their initial finding demonstrated that progenitor derived from iPSCs generated using lentiviral gene transduction led to the high incidence of highly aggressive tumors in immunodeficient mice after transplantation under the kidney capsule.
Using the highly immunodeficient NSG ™ mice [NOD.Cg - Prkdcscid Il2rgtm1Wjl / SzJ (005557)-RSB- as a host, they injected hu - PBMCs directly into the spleen along with HIV engineered to express luciferase (HIV - LucR).