When people walk or try to remember something, the activity in
the hippocampus becomes very rhythmic and these complex, rhythmic patterns appear, Mehta said.
In contrast, hippocampal engram cells were activated by natural cues on the second day after receiving a foot shock, but not on day 13 — indicating engrams in
the hippocampus become active immediately, but gradually fade into a «silent» state.
Not exact matches
The research suggests video games could
become a kind of
hippocampus training gym: they might some day help older people restore lost memory power and «keep that [memory] system in top form,» as Stark says.
Their team blocked neurogenesis in the
hippocampus — a seat of memory — with targeted irradiation, and then tested the rats for their ability to
become addicted to cocaine.
This region of the
hippocampus is associated with vasopressin, a hormone that plays a role in sexual bonding, motivation and other intensely social behaviors, which
become impaired in people with the disorder.
The link
became firmer after computerized tomography scans of alcoholic people revealed shrinkage in the
hippocampus, a brain center that tags information for storage as memories.
In previous studies on rodents, postdoctoral scholar Clemenson and others showed that exploring the environment resulted in the growth of new neurons that
became entrenched in the
hippocampus» memory circuit and increased neuronal signaling networks.
The study found that under psilocybin, activity in the more primitive brain network linked to emotional thinking
became more pronounced, with several different areas in this network — such as the
hippocampus and anterior cingulate cortex — active at the same time.
To answer this question of nature versus nurture, the researchers took cells that would grow to
become chandelier cells in the
hippocampus and transplanted them into the neocortex, and took cells that would grow to
become neocortical chandelier cells and transplanted them to the
hippocampus.
They
became faster learners, showed better recall, and displayed enhanced activity in the
hippocampus — the brain region responsible for learning and memory.
To see if Narp played a role in making these new cells in mice, the researchers injected a synthetic molecule, BrdU, to label and allow detection of newly created cells that would
become neurons in the
hippocampus.
And this applies to other areas of the brain as well as the
hippocampus, where we are beginning to ask questions about how these areas
become dysfunctional in mouse models of Alzheimer's disease.
The birth of new neurons in the mouse
hippocampus starts waning in early adulthood — well before cognitive decline
becomes obvious — so the researchers wondered whether boosting Tet2 levels in the adult
hippocampus could restore neurogenesis and potentially prevent the onset of cognitive decline later in life.
«This medial septum GABA circuit works through the local PV interneurons in the
hippocampus to instruct stem cells to
become activated or to stay quiet,» Song said.
In contrast, the
hippocampus appeared smaller in adolescents whose mothers were less supportive during the preschool period, even if their mothers
became more supportive in elementary or middle school.