Not exact matches
In the paper, the researchers conducted blood tests on a few dozen people and found that the presence of pre-existing adaptive immune responses in humans to either Cas9
homolog «may hinder the safe and efficacious use of the Cas9 / gRNA system to treat disease, and may even
result in significant toxicity to patients.»
On the other hand; neuroblastoma RAS Viral Oncogene
Homolog (NRAS) mutation is known to activate BRAF which
results in an anarchic melanocyte growth [30, 31].
NRF2 / SKN - 1: Increased levels of NRF2 in mice or its
homolog SKN - 1 in nematodes
results in slower aging and modestly extended life spans - normally NRF2 levels decline with age.
Together these
results show that deuterostome
homologs of Boule are also reproduction specific, like their protostome counterparts, but with a tendency toward testis - biased expression.