Sentences with word «homologue»
A homologue refers to something that is similar or comparable to another thing, often referring to similar structures or parts found in different organisms or species. It is used to describe the relationship between similar features or characteristics that have a common evolutionary origin. Full definition
Human TNFR1 successfully replaces its mouse homologue in the maintenance of splenic microarchitecture.
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Since the gene product of YME1 is a potent suppressor of mitochondrial DNA migration into the genome of the yeast Saccharomyces cerevisiae, Tiwari and Singh investigated the human homologue of the YME1 gene, called YME1L1.
The closest mammalian homologue of CCHa2 - R is Brs3, an orphan GPCR, which is a member of the bombesin - like peptide receptor family [51].
Here we have established that C. elegans possesses a close homologue of perilipin that is intimately involved in the regulation of lipid metabolism.
Expression of the p53 homologue p63 in early cervical neoplasia.
This suggests the task is accomplished through the integration of information in memory with some form of neural computation of the musical grammar in the right homologue of Broca's area.
It has been reported that the yeast homologue of DDX3, Ded1, is essential for translation initiation (6), and DDX3 is able to rescue Ded1 - deficient yeast mutants (4).
It has been observed that Non-CSD melanoma has a 75 % frequency of v - raf murine sarcoma viral oncogene homologue B1 (BRAF) mutations.
To unravel the structural basis for this ion selectivity, Ines Ehrnstorfer has determined the structure of a close bacterial homologue of DMT1 by X-ray crystallography.
Excitingly, the Asgard genome assemblies also encode homologues of some of the key components of the membrane trafficking machinery in eukaryotes, including regulatory small GTPases and longin domains.
hTNFR1KI is a humanized TNFR1 mouse with the human TNFR1 gene fully replacing its mouse homologue in all physiological and pathological functions.
Identification of a basal / reserve cell immunophenotype in benign and neoplastic endometrium: a study with the p53 homologue p63.
The zebrafish homologue of Parkinson's disease ATP13A2 is essential for embryonic survival.
Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor - binding and pH - dependent fusion activities.
Functional studies remain necessary to validate these hypothetical pathways, and to determine the specific pathway of ammonia conversion in the absence of a defined homologue for hydroxylamine oxidoreductase.
However, the work now published in PlosPathogens, showed that even though there are more than 60 million years of evolutive divergence between the human Kaposi sarcoma herpesvirus and its rodent homologue, LANA's functional mechanisms are preserved.
They could already show that important crop plants such as tomato and sugar beet also possess a functional homologue of NILR1 — an excellent basis for further specific breeding.
Jasper says researchers at the Buck are also testing homologues of rapamycin that are more specifically aimed at TOR Complex 1 — a key complex containing TOR that regulates cell growth and metabolism in all complex organisms.
The precision and consistency, with which the presenilin homologue MmIAP cleaved peptides, impressed the researchers.
We show that W01A8.1 is the previously unrecognized C. elegans homologue of vertebrate perilipins that possesses all functional domains characteristic for perilipins and functions in lipid metabolism at the level of lipid droplets.
More recently, I have demonstrated the feasibility of using fMRI in combination with pharmaco - genetic silencing to dissect the circuital basis of complex behaviors, and demonstrated for the first time that the mouse brain contains distributed resting - state functional connectivity networks, including plausible homologues of the human default - mode (DMN) and salience networks.
Human geneticists and cardiologists studying families with heart disease may discover, said Stainier, that a mutated form of the gata5 homologue occurs in some cases of heart disease, in which case the mutated form of the gene could serve as a marker of predisposition to the disease.
The simplified architecture of this archaic homologue, as well as its prokaryotic origin, allowed solving its X-ray structure in several conformations.
Importantly, the composite genomes of Asgard archaea encode homologs of actin genes, actin - binding proteins, multiple ESCRT complex homologues, and tubulin.
We will also assess whether the findings can be translated to a model of lethal murine malaria using Clone 10 - homologue DNA and protein subunit vaccines derived from Plasmodium berghei (ANKA) to induce immunity.
We also combine fold recognition approaches and 3D functional descriptors of proteins for genome - wide discovery of remote homologues members of different structural protein families (e.g. chemokines).
Wernicke's area homologue in chimpanzees (Pan troglodytes) and its relation to the appearance of modern human language.
Südhof then cloned the rat homologue a year later and called it synaptobrevin.
It belongs to the MAGUK family of proteins (membrane - associated guanylate kinase homologues), that also includes SAP90, PSD - 95 and many others (for review, see Montgomery et al 2004).
How a 45 % change in organ size might be achieved by either of these genes, each of which has a conserved homologue in the human genome, remains to be determined.