Selenium makes up a component of enzymes, called thyroid
hormone deiodinases, which help activate and inactivate thyroid hormones, which regulates your thyroid function.
Not exact matches
It's a five — the enzyme that converts T4 to T3 inactive thyroid
hormone to active thyroid
hormone is a 5
deiodinase enzyme.
Because it is the activity of these
deiodinases and transport of T4 and T3 into the cell that determines tissue and cellular thyroid levels and not serum thyroid levels, serum thyroid
hormone levels may not necessarily predict tissue thyroid levels under a variety of physiologic conditions.
To accurately assess thyroid function, it must be understood that
deiodinase enzymes are essential control points of cellular thyroid activity that determine intracellular activation and deactivation of thyroid
hormones.
The T3
hormone is known as the «metabolically active»
hormone and is produced by the conversion of the «metabolically inactive» T4
hormone (by the
deiodinase system).
Interrelationships among thyroxine, growth
hormone, and the sympathetic nervous system in the regulation of 5 - iodothyronine
deiodinase in rat brown adipose tissue.
Thyroid
hormone metabolism is impaired without selenium because iodine - based enzymes, called iodothyronine
deiodinases, can not be synthesized.
Although very minor amounts of selenium appear sufficient for adequate activity of
deiodinases, thus limiting the impact of its potential deficiency on synthesis of thyroid
hormones, selenium status appears to have an impact on the development of thyroid pathologies.
Selenium - containing
deiodinase enzymes are required to convert inactive thyroid
hormone to its active form.
«A wide variety of organochlorine compounds and pesticides have an effect on the thyroid
hormones in plasma, tissues and
deiodinase enzymes, which are in charge of stabilising the thyroid
hormones in tissues.»