In late 2013, he published what seemed to be a breakthrough study of patients with narcolepsy, which identified self - reactive T - cells that pursued
the hormone hypocretin.
Now a test of his spinal fluid showed a complete lack of
the hormone hypocretin, which regulates wakefulness.
Not exact matches
Here about 750 cells produce orexin (also known as
hypocretin), a
hormone that promotes wakefulness.
In the late 1990s, his team discovered that narcoleptics lack
hypocretin, a
hormone produced by a few brain cells that helps keep people and animals awake.
If it is detecting lowered leptin (and other
hormone) levels in the blood, it does several things: it up - regulates hunger signalling, it emphasizes sweet foods in doing so (partly why so many disordered eaters struggle with carbohydrates in particular), and it sends activation signals to
hypocretin neurons.
One notable source of excitation is corticotrophin releasing
hormone, which suggests that stress activates the activity of
Hypocretin Neurons.