Sentences with phrase «host cell entry»

Prototype foamy virus protease activity is essential for intraparticle reverse transcription initiation but not absolutely required for uncoating upon host cell entry.

Two - pore channels control Ebola virus host cell entry and are drug targets for disease treatment

Not exact matches

Dr Daniel Watterson, joint first author of the paper with Dr Jie Li, said that the antibody can block entry to the host cell, an essential step in the virus lifecycle.

In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.

Hemagglutinin (HA) and neuraminidase (NA) are the two predominant viral glycoproteins found in the viral envelope, and are the primary targets of the host immune system and are key factors in the entry and exit of influenza particles from host cells.

This indicates that MAIT cells are probably involved in the host response at the site of pathogen entry, and may regulate intestinal B - cell activity.

Together the two proteins form a complex that binds to one of two known cell surface receptors, mediating entry into the host cell [31].