Sentences with phrase «host cell pathways»

By tracking and understanding which host cell pathways are manipulated by these T. gondii proteins, scientists can identify potential new targets to develop more effective therapies against highly aggressive solid tumors.

Not exact matches

«Cardiac stem cells from heart disease patients may be harmful: Researchers discover molecular pathway involved in toxic interaction between host cells and immune system.»

«Researchers discover a new link to fight billion - dollar threat to soybean production: Scientists show that parasitic nematodes hijack vascular stem cell pathways to attack their hosts.»

«Not only can microbes exploit this in hosts, but host cells can exploit these pathways to instruct certain microbes to kill themselves.»

«These viruses are hijacking many of the host cell translation steps or pathways to favor the production of new virus progeny,» says Ruggieri.

Thus, the two small phages characterized for their lysis strategy, Qβ and the small DNA phage φX174, effect host lysis by targeting different enzymes in the multistep, universally conserved pathway of cell wall biosynthesis.

Microbes that cause diseases like HIV, malaria, and hepatitis C exploit and often activate the same checkpoint pathways — cell surface receptors such as CTLA4 and PD - 1 — to slow immune cells and prevent their elimination by the host.

«The parasite achieves this by sending proteins into the host cell that manipulate the host's own cellular pathways, enabling it to grow and reproduce.»

Due to an increasing body of evidence which suggests that the host immune response may be critical to the efficacy of oncolytic virotherapy, Shah and his colleagues also developed an immunocompetent melanoma mouse model and explored treating with both stem cell loaded oHSV and immune checkpoint blockers such as the ones that target the PD - 1 / PD - L1 pathway.

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

The discovery eventually led to the uncovering by others of two additional signaling pathways in mammalian cells that, together with Ire1, help maintain equilibrium in the face of stress, averting a host of diseases.

Epstein - Barr virus, the closest human relative of Kaposi's sarcoma - associated herpesvirus, mimics host B cell signaling pathways to direct B cell development toward a memory B cell phenotype.

Brucella ceti isolates infecting particularly dolphin hosts, showed further degradation of metabolite transport pathways as well as pathways related to cell wall / membrane / envelope biogenesis and motility.

Groundbreaking discovery challenges the conventional theory that infected host cells control latency and could open the door to new pathways

Formed by the merger of fat - eating mitochondria with glucose - eating bacteria, single - celled eukaryotes had to regulate their various metabolic pathways to keep themselves from becoming too fatty or too lean (and to control the urge of mitochondria to eat their hosts!).