IL17 is known to play a role in
host defense against cutaneous Candida albicans and Staphyloccus aureus infection (Cho et al., 2010; Conti and Gaffen, 2015) and to be induced in rats by Y. pestis (Comer et al., 2010).
Studying Ebola virus, they found that Ebola virus VP24 protein blocks interferon, an important part of
the host defense against virus detection.
They go on to suggest that «lowering levels of TNF may be an effective strategy in improving
host defense against S. pneumoniae in older adults,» and that, «although it may be counterintuitive to limit inflammatory responses during a bacterial infection, [some existing] clinical observations and our animal model indicate that anti-bacterial strategies need to be tailored to the age of the host.»
The findings suggest that dietary salt could have therapeutic potential to promote
host defense against microbial infections.
Spellberg is currently working on the immunology, vaccinology, and
host defense against highly resistant Gram negative bacilli, including Acinetobacter and carbapenem - resistant Enterobacteriaceae infections.
Not exact matches
SEOUL (Reuters)- South Korea's Lotte Group said Chinese authorities have halted construction at a multi-billion dollar real estate project after a fire inspection, amid worries in Seoul that Beijing is retaliating
against the country's plans to
host a U.S. missile
defense system.
The constant motion provided by the
host not only provides added access to food particles, but also a
defense against predators.
Dr Stotz continued: «This concept of plant ETI does not really explain the second line of
defense in the interaction of plant
hosts protecting themselves
against extracellular fungal pathogens — i.e. those foliar fungal pathogens that get into the leaf of the plant to exploit the space between its cells, known as the apoplast, to retrieve nutrients from the plant.
Bug bites itch because the
host's immune system mounts a
defense against the biter's saliva by flooding the area with histamines.
To learn how Mycobacterium tuberculosis mounts a
defense against a drug, Baliga is first looking within the bacterium, identifying the genes, proteins and other molecules that interact as the microbe infects a
host.
«What was really interesting is that the microRNAs specifically target
host genes that are involved in the plant's
defense against the parasite.»
This cross-species gene regulation, which includes genes that contribute to the
host plant's
defense against parasites, has never before been seen from a parasitic plant.
For years hormone replacement therapy was promoted as a
defense against a
host of age - related ailments.
Frogs» skins were known to secrete «
host defense peptides» that defend them
against bacteria.
This resulted in a staggering 50,000 virus -
host protein interactions, approximately 500 of which appeared to be involved in viral infection.By removing the interacting
host proteins from the cell one at a time, the researchers were able to determine what their functional contribution was in the infection process: whether the
host proteins were hijacked by the virus and used to spread infection, or whether they were part of a
defense mechanism
against the virus.
«This is quite good and convincing work that confirms
host defense activity of amyloid - β
against fungal and bacterial infections in animal models, and begins to unravel the mechanisms of antimicrobial activity of the protein,» said Kevan Hartshorn who studies innate immunity at the Boston University School of Medicine and was not involved in the study.
At the interface between the
host and the environment, mucosal barriers have several lines of
defense against invasive pathogens such as B. anthracis [6].
Genetic engineering of human antibodies;
host defense mechanisms
against microbial infection.
The findings, published in the Proceedings of the National Academy of Sciences, describe how myeloid differentiation factor (MyD88), a protein that plays a major role in mediating
host defense response
against invading pathogens, is tightly regulated to prevent uncontrolled inflammation.