Sentences with phrase «host disease by»
Reduction of graft - versus - host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.
http://www.jimmunol.org/ Not exact matches
And ambiguity is not a good thing for McDonald's, as evidenced by a tweet from ESPNW columnist and on - camera host Sarah Spain: While lovin» may indeed be greater than hatin», «Hatin» Beats Heart Disease.»
Until it ran afoul of the FDA, the company analyzed consumers» personal genomes in order to provide detailed summaries of their genetic risk for a host of common diseases (done through a spit kit sent by mail).
Many say that the antioxidant action provided by superfoods protects against cancer and heart disease, among a host of other ills — while others point out that few carefully controlled studies have been conducted.
Unlike the combination pill, progestin - only pills are considered compatible with breastfeeding by a host of organizations, including the Centers for Disease Control, the World Health Organization, the American Academy of Pediatrics, the American College of Obstetricians and Gynecologists, and Planned Parenthood Federation of America.
During remarks delivered at a forum hosted by the nonpartisan good government group Citizens Union, the Attorney General outlined what he believes is required to help «cure the disease» of public corruption, including a total ban on outside employment income for legislators, an end to per diems, rules reform to empower individual legislators, and a constitutional amendment to extend legislators» terms from two to four years.
At 7 p.m., Gibson will join Dr. Kenneth Liegner for a discussion of Lyme disease treatment, research, and legislation hosted by the Pawling Chamber of Commerce and the Town of Pawling, Lathrop Center, Pawling.
A vector is an organism that transmits disease by conveying pathogens from one host to another, serving as a route of transmission.
Gene drives enable a gene to spread rapidly through a population; there are plans to use them to combat mosquito - borne diseases by making the flies sterile or unsuitable as hosts for various viruses and parasites.
Swiss National Center for Prion Diseases in Zurich, headed by Adriano Aguzzi Site about BSE and vCJD at the British Department of Health Page about prion diseases hosted by the World Health Organization
Its influence on infectious disease is considered by Altizer and colleagues, who use examples from a wide range of host - pathogen systems to assess whether we are close to a predictive understanding of climate - disease interactions and their potential future shifts.
In a recent study published in the journal Nature Communications on 17 September, John Baines, Saleh Ibrahim and their colleagues of the Inflammation Research Excellence Cluster show that composition of skin microbiota is controlled by the host genome and that skin bacteria may have a greater influence on inflammatory diseases than previously thought.
The work was on the role of interleukin - 1 in the pathology of graft - versus - host disease (GVHD), the mechanism by which the new immune system, which a patient receives as a bone marrow transplant, attacks the patient's body following the transplantation.
Beard explained that Zika infections, like almost all diseases spread by mosquitoes, hinge on two variables: infected hosts and capable carriers.
If dozens of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed at last of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety of neurological disorders, including Parkinson's disease, mild cognitive impairment (MCI), Tourette's and schizophrenia.
These programs, which were discussed last month at a rare - diseases conference hosted by the Wellcome Trust Sanger Institute near Cambridge, UK, aim to provide a genetic diagnosis that could end years of uncertainty about a child's disability.
So the devils» frequent facial injuries could actually play a role in causing the cancer to arise, as well as providing a route by which the diseases can jump from host to host.
«But then we found that certain diseases, like irritable bowel syndrome, seem to be caused by imbalances in the organisms that communicate with the host.
The transmission of emerging diseases has also been enhanced by a host of modern practices and technologies.
«Eradicating mosquitoes by eradicating a key host provides a relatively unexplored way to combat the diseases mosquitoes transmit,» Young said.
Wild boar and red deer are key hosts of bovine tuberculosis — a chronic, infectious disease mainly caused by Mycobacterium bovis — in southern Europe, with the incidence of TB in these animals particularly high in certain areas of Spain.
Cortisol is a stress hormone produced by the hypothalamic pituitary adrenal (HPA)- axis which, if overproduced, can contribute to a host of chronic ailments including cardiovascular disease and mental illness.
They must also deal with a host of challenges tied directly to the environment and potentially amplified by climate change, including warming waters, increasing ocean acidity and the spread of diseases that can decimate shellfish stocks.
The approach of targeting a host response required by a pathogen to cause disease rather than targeting the microbial pathogen is gaining wide support in the medical community.»
They do their dirty work by infiltrating bacteria, including disease - causing germs, and destroying them from within: After latching onto bacteria, the phages bore inside and hijack the bacteria's genetic machinery, turning them into phage factories that eventually make so many copies that the cells burst, killing off the host.
«Protein derived from parasite has potential to alleviate debilitating disease: Chemotherapy - induced hemorrhagic cystitis alleviated by protein that parasites use to keep hosts alive.»
The authors propose that all law enforcement - related deaths — including people killed by police as well as police killed in the line of duty — be treated not just as criminal data but as a «notifiable condition,» and that they be reported to the Centers for Disease Control (CDC) by public health and medical professionals and published on a weekly basis, as are a host of other conditions ranging from poisonings to pertussis to polio.
«Dihydroartemisinin - piperaquine is more effective than artemether - lumefantrine, and has fewer side effects than artesunate - mefloquine» concludes a systematic review published by the Cochrane Infectious Disease Group, hosted by LSTM.
In a comprehensive and complex molecular study of blood samples from Ebola patients in Sierra Leone, published in Cell Host and Microbe, a scientific team led by the University of Wisconsin - Madison has identified signatures of Ebola virus disease that may aid in future treatment efforts.
Hosts infected by viruses found new uses for the genetic material the agents of disease left behind; metabolic enzymes somehow came to refract light rays through the eye's lens; mammals took advantage of the sutures between the skull bones to help their young pass through the birth canal; and, in the signature example, feathers appeared in fossils before the ancestors of modern birds took to the skies.
Martin sees disturbing parallels between the cultural representations of people who fall by the wayside in the world of work — through unemployment, «deskilling» or lack of training — and those who fall ill as a result of «inferior» immune responses, leading to AIDS, cancer or a host of other diseases.
A new test may reveal which patients will respond to treatment for graft versus host disease (GVHD), an often life - threatening complication of stem cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.
Graft - versus - host disease is a condition in which the patient's immune system is attacked by the donor stem cells.
The mosquitoes» undetectable departure, which lets them avoid being smacked by an annoyed host, may be part of the reason A. coluzzii so effectively spreads malaria, a parasitic disease that kills hundreds of thousands of people each year.
Even worse, a hallmark of Leishmania biology happens to be its capacity to adapt to a variety of unpredictable fluctuations inside its human host, notably pharmacological interventions, with important consequences on disease outcome as demonstrated by the emergence of drug resistant clinical isolates.
The team notes that the results of their study suggest that current means of testing and approving food additives may not be adequate to prevent use of chemicals that promote diseases driven by low - grade inflammation and / or which will cause disease primarily in susceptible hosts.
Microbes that cause diseases like HIV, malaria, and hepatitis C exploit and often activate the same checkpoint pathways — cell surface receptors such as CTLA4 and PD - 1 — to slow immune cells and prevent their elimination by the host.
Earlier work by Skinner has found epigenetic effects from a host of environmental toxicants, connecting plastics, pesticides, fungicide, dioxin and hydrocarbons to diseases and abnormalities as many as three generations later.
An international study led by researchers at Monash University» Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.
As an example of a disease whose genetic basis not only is felt to be much simpler than that of malignancies, but also is affected by host genomic and environmental complexities, consider sickle cell disease.
As expected, xenogeneic graft versus host disease (GVHD), assessed clinically by dermatitis and hair loss, was observed in mice receiving cells treated with both R5 - ZFNs and X4 - ZFNs in the absence of HIV challenge.
«Alzheimer Disease: Host Immune Defence, Amyloid - β Peptide and Alzheimer Disease,» by Todd E. Golde, Nature Reviews Neurology, July 2016.
Below we explore some of the key ethical and social considerations, as well as legal and policy considerations, that are relevant to host genomic discoveries, followed by particular examples of ELSI issues that may arise if we apply genomic discoveries to four specific infectious diseases that differ in a number of ELSI - relevant characteristics (Table1).
The findings mapping the structural landmarks or epitopes recognized by CD8 + cells appear in the January 12, 2017, issue of Cell Host & Microbe and provide an important tool to track Zika - specific T cells in the context of different disease models.
After an initial acute disease state, that is kept in check by host immune response, bacteria as Pseudomonas aeruginosa and Staphylococcus aureus can establish persistent infections and colonize the host by evading immune surveillance.
New research from La Jolla Institute for Allergy and Immunology lays the groundwork to parse how the virus interacts with its host and causes disease by pinpointing CD8 + T cells, a subset of T cells more commonly known as cytotoxic or killer T cells, as important gatekeepers that control Zika infection or limit the severity of disease.
Considerations of privacy and autonomy are being challenged on a massive scale by WGS and whole - exome sequencing (WES), technologies that are expected to contribute to our understanding of host genomics in the context of infectious disease.
The horses had picked up the disease while feeding beneath trees inhabited by fruit bats, which are Hendra's natural host species.
The awards span the broad mission of the NIH and include groundbreaking research, such as engineering immune cells producing drugs at the site of diseased tissue; developing a sensor to rapidly detect antibiotic resistance of a bacterial infection; understanding how certain parasites evade host detection by continually changing their surface proteins; and developing implants that run off the electricity generated from the motion of a beating the heart.
Bleaching can be caused by a host of human - induced and natural factors such as (top) intense sunlight combined with elevated water temperature; (middle) diseases caused by bacteria, fungi, and viruses; and (bottom) coastal pollution that reduces water quality and increases susceptibility to bleaching.