Sentences with phrase «host gene expression»

Changes in the Rumen Epithelial Microbiota and Host Gene Expression of Cattle in Response to Alterations in Dietary Carbohydrate Composition.Petri RM.

«Gut's microbial community shown to influence host gene expression.»

Secretory antibodies in breast milk promote long - term intestinal homeostasis by regulating the gut microbiota and host gene expression

Not exact matches

When oxygen is scarce, however, HIF - 1α starts to accumulate and turns on the expression of a host of genes that assist in promoting and increasing oxygen delivery to hypoxic regions.

Even when the genes are more fully understood, scientists will have to find the right host organism to express the genes, optimize that expression and try to get them to produce as much of the oil as possible — all of which involves a lot of basic research and time, he said.

Beyond their participation in host defense, increasing evidence suggests that these modifications also play important roles in the regulation of gene expression, virulence and antibiotic resistance.

Dodder, a parasitic plant that causes major damage to crops in the U.S. and worldwide every year, can silence the expression of genes in the host plants from which it obtains water and nutrients.

The parasite inserts microRNAs into the host that can silence the expression of host genes.

The upshot of the study, another indictment of the so - called Western diet (high in saturated fats, sugar and red meat), reveals how the metabolites produced by the bacteria in the stomach chemically communicate with cells, including cells far beyond the colon, to dictate gene expression and health in its host.

«The bugs are somehow driving gene expression in the host through alteration of the epigenome,» explains John Denu, a UW - Madison professor of biomolecular chemistry and a senior researcher at the Wisconsin Institute for Discovery, and a co-author of the new study.

The researchers went into this study expecting to find that the microbes signaled the host to open up areas of chromatin to activate gene expression in the gut.

Profiling the expression patterns of host genes revealed that the insect significantly increases the abundance of B vitamin transporters and activation enzymes when reared in the absence of its gut microbes.

«The bugs are somehow driving gene expression in the host through alteration of the epigenome,» explains John Denu, a UW — Madison professor of biomolecular chemistry and a senior researcher at the Wisconsin Institute for Discovery, and a co-author of the new study.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during ¿ - herpesviral infection.

These datasets will allow the characterization of how genetically different parasites that cause distinct types of human toxoplasmosis alter the expression of protein - encoding and miRNA - encoding genes in both the human host and the parasite.

Along this line, our primary research goals are directed towards understanding how noncoding RNAs and their RNA - binding proteins are integrated in to the regulation of gene expression and modulation of the host immune response during gammaherpesvirus infection.

A novel way of approaching protection - based therapeutics for glaucoma should derive from evidence accumulating over two decades in stroke and cardiac arrest: That simultaneously activating a variety of self - defense responses in cells with stressful «conditioning» stimuli induces the expression of a host of genes that promote cell survival.

It allows the analysis of host immune gene expression in relation to vaccination, infection, disease or therapy in larger cohorts.

With respect to the host's transcriptome, alcohol feeding was associated with down - regulation in gene and protein expression of bactericidal c - type lectins Reg3b and Reg3g in the small intestine.

Four strategies for gene expression are apparent during the parasites» life cycle: (i) housekeeping; (ii) host - related; (iii) strategy - specific related to invasion, asexual replication, and sexual development; and (iv) stage - specific.

Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.

Relative expression of the host antimicrobial peptide genes was calculated using host Rpl32 as a reference.

The former causes uptake of viral genomes by host cells and leads to subsequent gene expression (25).

Therefore, these reference genomes can also enable further studies, such as identifying gene expression changes that explain multidrug resistance and host interaction.

In the search for a defining feature of the Escherichia coli that cause urinary tract infections, comparative transcriptomics and infection models show that infection depends on both the host environment and gene expression levels in the bacteria.

Modulation of Host Cell Gene Expression through Activation of STAT Transcription Factors by Pasteurella multocida Toxin

Oggioni MR, Pozzi G.A host - vector system for heterologous gene expression in Streptococcus gordonii.Gene.

They found that, whether in cultured cardiomyocytes or the cardiac and skeletal muscles of live B6129SF2 mice, the BCAAem not only promotes mitochondrial biogenesis but boosts the expression of a host of other potentially life span - extending factors, including proteins in the ROS defense system and SIRT1, the mouse equivalent of the yeast longevity gene SIR2.

Furthermore, there are no genes unique to M. bovis, implying that differential gene expression may be the key to the host tropisms of human and bovine bacilli.

Though isolates were identical by laboratory typing methods, we uncovered many differences in their genomes, in gene expression, and in their interactions with host cells.

From these studies, it was evident that there was a differential expression of host neuroimmune genes in the clinical groups, emphasizing the divergent biological environments in the HIV compared to the ODC brain specimens.

The altered microbiota was associated with changes in colonic short - chain fatty acid (SCFA) concentrations, colonic - tissue gene expression (Gsta2 and Ela1), and host physiology (serum metabolite profiles and colonic goblet cell numbers).