Sentences with phrase «host metabolism»

«Recent work by other groups has shown that bile acids act as signalling molecules in the host, almost like a hormonal network, with an ability to influence host metabolism.

Still, he adds, «there's a lot more basic biology that will need to be worked out to fully appreciate the mechanisms that cause sweeteners to alter gut microbial community composition and function, and how in turn this shapes host metabolism.»

«We found that when you perturb gut microbes early in life among mice and then stop the antibiotics, the microbes normalize but the effects on host metabolism are permanent,» says senior author Martin Blaser, MD, the Muriel G. and George W. Singer Professor of Translational Medicine, director of the NYU Human Microbiome Program, and professor of microbiology at NYU School of Medicine.

«Our findings indicate that exercise is another important factor in the relationship between the microbiota, host immunity and host metabolism, with diet playing an important role,» conclude the authors.

Comprehensive studies of changes in the resident intestinal microbiota, host metabolism and immune system reactivity in T1D patients and cohorts at risk of T1D, as well as the correlation with clinical data, anti-islet antigen antibodies and HLA genotypes will enable identification of novel biomarkers and biosignatures, and insights into the pathophysiology of the onset of T1D.