Sentences with phrase «how cell cycle»

Not exact matches

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.

In November 2010 Japanese researchers announced online in Analytical Chemistry that they had built a chip that simultaneously tests how liver, intestine and breast cancer cells respond to cancer drugs, and in February 2010 scientists publishing in the Proceedings of the National Academy of Sciences USA developed a microscale replica of the human liver that allowed them to observe the entire life cycle of hepatitis C, a virus that is difficult to observe in cultured cells.

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24 - hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA - protein complex of the cell.

Igoshin said that when the researchers set out to find how sporulation decisions were timed to the cell cycle, several studies including prior work by team members, provided a significant clue: Under starvation conditions, the activity of the master regulator gene had been shown to spike once per cell cycle.

In the new study, Narula, Igoshin and collaborators set out to explain how B. subtilis times its sporulation decision with its cell - division cycle, a programmed series of events that cells normally follow to reproduce.

Alex Dammermann and his team from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna, together with his collaborators from the Institute of Molecular Pathology (IMP), have been investigating how the duplication of one key component of the cell division machinery, named centrioles, is coordinated with the cell cycle — the series of events that lead to a cell's division.

Lee's study results, which appear in the July 16, 2015 issue of Nature Communications, revealed new understanding about how 14 -3-3 sigma — a cell cycle «controller» - regulates cancer metabolic programming, thus protecting healthy cells from turning into tumor - producing factories.

When Corry and first author Wen Lu, a graduate student in immunology, sought to determine how the microRNA worked, they found histone deacetylase 4, a protein that plays a role in the regulation of DNA transcription, cell cycle and development.

Now researchers have found even more strangeness in how the sex chromosomes behave during the cell cycle.

A novel mechanism — similar to how normal tissue stem cells respond to wounding — might explain why bladder cancer stem cells actively contribute to chemo - resistance after multiple cycles of chemotherapy drug treatment.

«The cancer stem cells actively regrow and respond to the induced damage or apoptosis (cell death) caused by chemotherapy in between the different cycles, similar to how normal tissue stem cells respond to wound - induced damages.»

Mónica Bettencourt - Dias adds: «I am very proud of this paper, we knew the cell cycle clock and centriole formation had to be linked - otherwise how would cells ensure the right copy number is made?

Nathaniel Hoyle of the Laboratory of Molecular Biology in Cambridge, UK, and his team have been investigating how the time of day affects wound healing, after they discovered that genes in a type of skin cell switch on and off during day - night cycles.

Researchers describe how a microRNA can affect both pluripotency and cell cycle progression in human pluripotent stem cells

How the vital processes of cell cycle control (with the final event of cytokinesis) and signalling for cell wall biosynthesis are exactly coordinated remains to be determined.

Also, the expression of NUDIX in normal and cancer tissues, and how knock - down of these enzymes affected proliferation and cell cycle progression in both cases, were investigated.

Hall and Rosbash then discovered a protein, named PER, that was made by the period gene, and figured out how it worked through a feedback mechanism — its own expression in the cell would cause PER to build up in the nucleus and would eventually effectively shut off the period gene, allowing it to cycle on and off on a daily schedule.

To uncover how groups of cancer cells achieve functional diversity (through RNA) to survive chemotherapy, Lopez - Diaz dosed dishes of human pre-cancer and metastatic breast cancer cells with the cancer drug paclitaxel for a week and then removed the drug for a few weeks, mimicking the treatment cycle for a cancer patient.

Moreover, the Galli group studies cell cycles that lead to polyploidization, such as endoreplication and endomitosis, and how these cycles are regulated in normal physiology and in disease.

This contiguous set of protein - to - protein and protein - to - DNA interactions provided a direct explanation of how TGF -(beta) negatively controls the cell cycle.

It is currently largely unclear how cells initiate these alternative cell cycles, and what their functional importance is for tissue homeostasis.

Altieri and his team are currently focused on three programs to understand the biology of survivin with respect to cell cycle progression, in particular, mitosis, cell survival and the cellular stress response and how exploiting these pathways may provide new cancer therapeutics.

There, they collected chemical maps from actual coin cell batteries filled with iron fluoride during battery cycling to determine how well they perform.

We are interested in the mechanisms of tRNA aminoacylation in mitochondria, and how this reaction is used to coordinate the cycle of mitochondria with the rest of the cell's metabolism.

Researchers at SciLifeLab / Uppsala University headed by Johan Elf have used a combination of microfluidics and image analysis of E. coli with fluorescent labels on the replication machinery to study how the replication and division cycles are coupled in individual cells.

Altogether, this study reveals how a kinase integrates and transduces multiple signals to control key cell - cycle transitions during Plasmodium gametogenesis.

The ultimate goal is to understand intricacies in the steps of the virus life cycle, such as how the virus enters the host cell, to direct antivirals to those specific steps, Hafenstein said.

Swanton was stunned to learn how similar fundamental cellular processes were between humans and yeast, and how cell - cycle regulation is related to cancer development.

This includes a detailed, yet a fully understandable description of the biochemistry of aerobic respiration versus anaerobic fermentation, glycolysis, the Krebs Cycle, the electron transport chain, lactic acid overproduction and how cancer cells develop as a result of mitochondrial metabolic dysfunction leading to genetic errors, resulting in metastasis.

Year 4 Science Assessments Objectives covered: Recognise that living things can be grouped in a variety of ways Explore and use classification keys to help group, identify and name a variety of living things in their local and wider environment Recognise that environments can change and that this can sometimes pose dangers to living things Describe the simple functions of the basic parts of the digestive system in humans Identify the different types of teeth in humans and their simple functions Construct and interpret a variety of food chains, identifying producers, predators and prey Compare and group materials together, according to whether they are solids, liquids or gases Observe that some materials change state when they are heated or cooled, and measure or research the temperature at which this happens in degrees Celsius (°C) Identify the part played by evaporation and condensation in the water cycle and associate the rate of evaporation with temperature Identify how sounds are made, associating some of them with something vibrating Recognise that vibrations from sounds travel through a medium to the ear Find patterns between the pitch of a sound and features of the object that produced it Find patterns between the volume of a sound and the strength of the vibrations that produced it Recognise that sounds get fainter as the distance from the sound source increases Identify common appliances that run on electricity Construct a simple series electrical circuit, identifying and naming its basic parts, including cells, wires, bulbs, switches and buzzers Identify whether or not a lamp will light in a simple series circuit, based on whether or not the lamp is part of a complete loop with a battery Recognise that a switch opens and closes a circuit and associate this with whether or not a lamp lights in a simple series circuit Recognise some common conductors and insulators, and associate metals with being good conductors