Sentences with phrase «how cell signaling»

One aspect of their work studies how cell signaling pathways, such as those that initiate cell growth or death, are affected by the nanostructures and microstructures of implant materials such as titanium.

Andrew Huberman, PhD: We know a lot about the biology of healthy ganglion cells, both in terms of what those connections look like and how those cells signal information about the visual world to the brain, in effect, how they tell the brain what's out there in the visual world.

Not exact matches

And, perhaps most strikingly, a team at a gaggle of New York research institutions published a paper showing how they'd used hPSCs to cook up — in just days, rather than several months — cortical neurons (critical central nervous system cells) that had normal electrophysiological signaling properties.

In fact, I'm knockin» on doors yesterday and a guy was telling me how he's right in Wynantskill and he can't even get a cell phone signal at his house.

Researchers thought that molecular signals told cells where and how to rebuild, but new evidence suggests there are other forces at play.

Joe W. Ramos, PhD, deputy director of the UH Cancer Center and collaborators focused on investigating how these oncogenes and related signals lead to dysregulation of normal processes within the cell and activate highly mobile and invasive cancer cell behavior.

When researchers sequenced the sponge's genome in 2010, they found genes that help individual cells cooperate as a group: how to divide, send signals to one another, and distinguish between friends and outsiders.

For example, to tease out what various sound signals might mean, the researchers had to figure out how kelp tissues respond to sound (turns out that it's highly dependent on alginate content, a gummy cell wall component of kelp).

«The pathway mainly involves signalling via the brains» immune cells, and thus differs from how today's drugs operate.

Today is the 86th birthday of Sir Bernard Katz, a German - born English physiologist who elucidated how nerve cells transmit signals.

It was already known that cold temperatures stimulate brown fat, but was unclear how the body signals that message to its cells.

Professor Taylor, who co-ordinated the research, says: «Our findings provide the very first insight into how biochar stimulates plant growth — we now know that cell expansion is stimulated in roots and leaves alike and this appears to be the consequence of a complex signalling network that is focussed around two plant growth hormones.

The group then ran dozens of microscopy tests with Dan Wagner, Rice associate professor of biochemistry and cell biology, to see how different formulations and amounts of biochar affected cell signaling.

A team led by Carnegie's Wolf Frommer has revealed how membrane proteins were networked with each other and with the signaling proteins inside the cell.

Kilian said these questions range from the basic — how macrophages signal to the breast cells — to the more long - term: Can therapeutics be used to disrupt that communication?

By measuring the signal returned from the transplant locations, she was able to determine how many of the cells survived.

Researchers still don't know how this range corresponds to their versatile functions, but being more like a string than like a lump with keyholes means that a protein can make many contacts with other molecules to regulate the network of signals that drives the cell.

The researchers investigated how Suv39h1 employs a positive feedback loop to chemically tag thousands of adjacent histones, thus signaling the cell to stow away these underlying, unnecessary DNA sequences.

Investigators are working to break the code in stem cell communication by determining how stem cells signal one another and other cells.

An interdisciplinary scientist is needed to demonstrate how the mechanical properties of the culture system alter signaling in the cells.

But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other biomolecules that surrounds cells and plays a vital role in their shape, movement and signaling functions.

Extend that logic to a cell, though, and things can get ugly: Because IDPs regulate how different components of the cell communicate with one another, having extra copies floating around could leave them sending signals that shouldn't get sent.

That mutation helps determine how the various cells in the worm respond to insulin and IGF signaling.

Exactly how they detect problems was unclear, but researchers now show that they respond to an SOS signal from dying cells that is relayed throughout the brain.

And it's essential to understand how neurobiological processing conducted by molecules and cells and electrical signaling gets translated into behaviors, from simple bodily movements to complex social interactions.

Riffell and his colleagues hope these nerve cell recording experiments will help them understand how insects integrate and interpret different signals from their environment and use this information to make decisions.

Manipulating how cells respond to signals is key to developing new medications.

A signaling pathway is how developing cells get instruction on what types of cell to become, such as a liver cell, a skin cell, a brain cell, etc..

Biophysicists led by Professor Erwin Frey, who holds the Chair of Biological and Statistical Physics at LMU, have now shown theoretically how this can be accomplished even when only a subset of cells actually emits the requisite signals.

The team's next step is to zoom in on the molecular mechanisms that control how the Wnt signaling pathway interacts with the nail stem cells to influence bone and nail growth.

The study provides evidence for how FGF23 signals to cells by forming a complex with a-Klotho and the two other molecular partners.

The daf - 2 gene is also part of a signaling pathway that influences how well cells age and cope with stress.

«Scientists determine structure of enzyme linked with key cell - signaling protein: Findings aid understanding of how modifications to cell - signaling protein affect its action in turning genes on and off.»

Still unclear is how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that controls how well cells resist or repair these stresses.

It's similar to how GPS uses the timing of satellite signals to determine the position of your cell phone — and it would mean spacecraft would no longer have to rely on radio telescope communications to find their coordinates.

In their work, the researchers also show how TGF - beta can be used in stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotonin.

The U-M study explains how increased cAMP in fat cells promotes the secretion of the hormone interleukin - 6, which signals the liver to stop producing glucose — thus improving overall blood sugar levels in obese diabetic mice.

I ache to see your action potential in action To be blinded by the searing speed of your electric signal As it sparks from node to node To behold the violent beauty of vesicles fusing with your presynaptic membrane — Pouring their contents into your synaptic cleft How I wish to be your postsynaptic cell So that I may be flooded by your molecules

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.

To complete the picture, two such somatic protective cells surround each maturing sperm cell, and those encysting somatic cells send signals to the sperm cell on how and when to mature.

In prior, unrelated experiments, the same species of worm had become hypersensitive to smell when its nerve cells experienced problems with dopamine signaling, a cellular process that helps control how readily cells can communicate with one another.

But how do cells sense these scent signals, which become weaker and weaker with increasing distance from the source?

Following on from this discovery, the next fundamental question to answer is, how is this signal being transmitted from the chloroplast to the nucleus to change gene expression within the cell?

How do cells «read» this weakening of the signal — technically referred to as a signal gradient — in order to steer their growth or movement towards the signal's source?

A strategic focus is to continue to develop computational tools (such as KinomeXplorer, NetworKIN, and NetPhorest) and to deploy these on genome - scale quantitative data obtained by, for example, mass spectrometry, genomic, and phenotypic screens to understand the principles of how spatio and temporal assembly of mammalian signaling networks transmit and process information at a systems level in order to alter cell behavior.

In addition, the analysis provided some hints about how chemotaxis evolved from a simple signaling network that responds slowly to environmental cues — primarily by turning on genes — to a multiprotein system that can quickly alter a cell's course.

«The beauty of this study is that we now have a system in which we can investigate how a signaling cell uses these two genes Yorkie and Scalloped, which have never before been shown in blood, to direct specific cells to be made,» said Dr. Martinez - Agosto, associate professor of human genetics.

«Intracellular signaling depends on these protein modifications — so by doing these analysis, we know not only what's in the cell, but also how the cell organizes and communicates internally.»

The scientists found that neurons lacking BAI1 show changes in long - term potentiation (LTP) and long - term depression (LTD): how the cells respond to patterns of incoming electrical signals.

Cell receptors will receive a signal from outside, and when it binds, that information is transmitted through the receptor to other proteins within the cell, [creating] a chain of events to change how the gene works in the cCell receptors will receive a signal from outside, and when it binds, that information is transmitted through the receptor to other proteins within the cell, [creating] a chain of events to change how the gene works in the ccell, [creating] a chain of events to change how the gene works in the cellcell.