Sentences with phrase «how cell signaling pathways»

One aspect of their work studies how cell signaling pathways, such as those that initiate cell growth or death, are affected by the nanostructures and microstructures of implant materials such as titanium.

Not exact matches

«The pathway mainly involves signalling via the brains» immune cells, and thus differs from how today's drugs operate.

A signaling pathway is how developing cells get instruction on what types of cell to become, such as a liver cell, a skin cell, a brain cell, etc..

The team's next step is to zoom in on the molecular mechanisms that control how the Wnt signaling pathway interacts with the nail stem cells to influence bone and nail growth.

The daf - 2 gene is also part of a signaling pathway that influences how well cells age and cope with stress.

Still unclear is how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that controls how well cells resist or repair these stresses.

«For example, mouse mammary tumors shared a signaling pathway that is found in human lung cancer and controls how cells reproduce and move from one location to another.»

Jasper says TOR can be regulated by a number of stimuli, and researchers are now attempting to better understand how the activity of this signaling pathway is controlled in stem cells.

Scientists at the Wyss Institute at Harvard University set out to solve the mystery of how blood flow keeps the vessels intact and, to their surprise, discovered a completely new cell signaling pathway that is a promising target for drugs to treat a variety of debilitating conditions.

A fundamental question is how signaling pathways are regulated in time and space to facilitate directional migration of cells.

Still unclear is how enhanced signaling through the insulin pathway protects against obesity, although the researchers speculate that it might boost energy consumption by liver and muscle cells.

However, her research group has not yet identified how to make stem cells yield entirely dI1 or entirely dI3 cells — perhaps because another signaling pathway is involved, she said.

It locks onto and deactivates a protein, Smoothened, that activates the Hedgehog signaling pathway, which orchestrates how embryonic stem cells develop.

But what scientists did not know is how the mutations trigger a molecular signaling pathway that leads to the death of photoreceptor cells.

We therefore believe that a targeted inhibition of this specific signalling pathway, which controls how the cells in the vessel walls are connected, might work better as a cancer therapy than the more general VEGFA inhibition that is used today,» says Lena Claesson - Welsh.

We are investigating the genes that are the target of this pathway, how it influences the cells of growing worms, the size differences between the sexes (hermaphrodite worms are larger than males), and the way in which it mediates signals from the environment.

Major studies how cancer cells hijack specific signaling pathways to spread throughout the body, using drugs and genetic manipulation to probe the inner workings of these out - of - control cells.

To better understand how insulin signaling affects beta - cell growth, the Joslin scientists next studied a pathway involving a protein called FOXM1.

Here we show how second messengers relevant to the Gq signaling pathway can be detected in living cells using assays for DAG, PIP2, and Ca2 +.

Her goals are to continue working to understand how the dynamics of p53 and other signaling pathways important in cancer control cell fate decisions.

Her research focuses on understanding how signaling pathways control gene expression, using T cells and other cells of the immune system as models.

A Emory News item on a helpful part of the microbiome focuses on how the same type of bacteria â $ «lactobacilli â $ «activates the same ancient signaling pathway in intestinal cells in both insects and mammals. It continues a line of research from Rheinallt Jones and Andrew Neish on how beneficial bacteria stimulate wound healing by activating ROS (reactive oxygen species).

In an exclusive interview with SelectScience, the founder of Montana Molecular, Anne Marie Quinn, shares how her team measures, in real time, multiple GPCR signaling pathways inside a living cell using the CLARIOstar microplate reader.

«Here, we show how a common growth signaling pathway in cells can destroy one of the brakes on cell division to allow cell division to move forward,» Emanuele said.