Researchers have identified a fused gene in moss that provides insight into
how cells build their external walls.
Not exact matches
Scientist are also approaching it from the other side too, gradually stripping away at prokaryotic
cells to see
how stripped down they have to become for life to «stop,» while others continue to
build up from coacervates and protobionts.
The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic
building block of all life, the
cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines
how various organisms interrelate.
In November 2010 Japanese researchers announced online in Analytical Chemistry that they had
built a chip that simultaneously tests
how liver, intestine and breast cancer
cells respond to cancer drugs, and in February 2010 scientists publishing in the Proceedings of the National Academy of Sciences USA developed a microscale replica of the human liver that allowed them to observe the entire life cycle of hepatitis C, a virus that is difficult to observe in cultured
cells.
The algorithm was
built using tools the researchers developed to define
how T
cell receptors recognize a part of the antigen called the epitope.
How come a
cell can behave like a tiny computer or
build a complex shell?
Building artificial
cells will tell us much about the origins of life — and may explain
how Darwinian evolution began, says Nobel laureate Jack Szostak
They used this novel simulation approach to
build a model of a sperm
cell that demonstrates cellular movement from individual dynein protein molecules in the tail all the way up to the whole
cell, allowing them to observe
how changes at the atomic level are reflected in larger - scale structures.
The panels show
how individual melanoma
cells came together to
build a tumor in just four hours.
«Understanding the role of «noisy» fluctuations can help us understand
how bacteria diversify to survive,» Elowitz says, «as well as
how cells specialize to
build multicellular organisms.»
It allows biologists without strong math or computer programming skills to
build models and simulate
how a
cell functions.
When
building these structures, the location of the
cells is significant in that it will impact
how the structure will ultimately function.
Young, in 1994, also furthered the understanding of circadian rhythms by explaining
how the protein that
builds up in
cells during the night got there in the first place.
Her most recent paper — this one published in PNAS, the official journal of theNational Academy of Sciences — explains a totally new way that viruses operate in
building particles and
how viruses can change shapes to interact with their host
cells.
But their overriding interest in BPTES, says Slusher, was in
how it works: by blocking the production of glutamine, an amino acid that acts as a
building block of
cells and is used frequently by pancreatic cancers to create more cancer
cells.
The Campàs lab is studying several of these questions, including
how limbs are
built and
how mechanical changes in tumors affect the behavior of malignant
cells and the growth of the tumor.
A series of fine - tuned maps of DNA packaging in human
cells reveal dynamic new views of
how the genome's instructions are carried out to
build a person.
By comparing the numbers of nerve
cells, or neurons, among eight species of carnivores (ferret, banded mongoose, raccoon, cat, dog, hyena, lion and brown bear), researchers now have a better understanding of
how different - sized brains are
built.
«Josh wanted someone to come in and
build a model of single AII
cells to try and understand
how the AII works as an input / output device,» Cembrowski explains.
So, [what] we want do is, we want to give a solar
cell or a battery or an ultracapacitor the genetic information that says this is
how to
build this device.
And once you have the DNA that tells you
how to
build that device, all you have to do is keep amplifying it and basically passing it on to your offspring, which say this is
how to
build a solar
cell or this is
how to
build a battery, and that's what is the main driving force in our labs.
And researchers must figure out
how to
build in some core features: the necessary blood vessels, immune - system
cells called microglia and connections from other brain regions, such as the thalamus and cerebellum.
Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by
how much messenger RNA — the gene's instruction guide that tells a taste
cell to
build a specific receptor — their
cells make.
Building on previous work from Yuan's lab showing that the activity of RIPK1 could be blocked by a chemical called necrostatin - 1, the research team tested
how ALS
cells in lab dishes would respond to the same treatment.
Researchers used data from different people's genotypes and metabolism to
build personalized models that simulate
how a drug will affect a particular set of
cells in the body.
They
built a mathematical model of a
cell with a helix in it, and calculated
how big the surface waves needed to be, and
how fast the helix had to turn.
With the three - year grant, Vanapalli and his collaborators Boyd Butler in the Department of Biological Sciences and Everardo Cobos at the Texas Tech University Health Sciences Center, will
build microfluidic devices that mimic blood flow to study
how tumor
cells move inside capillaries,
how they squeeze through tight spaces, whether they are subject to fragmentation and
how they become stuck.
But it's still a mystery
how the amino acid
building blocks were first assembled according to coded nucleic acid templates into the proteins that formed the machinery of all
cells.
In 1961, Marshall Nirenberg and Johann Matthaei cracked the first «word» in that code, revealing exactly
how DNA instructs the
cell to
build proteins.
His lab will also continue working to understand why the
build up of cholesterol causes neurons to die and
how HPβCD is able to remove cholesterol from
cells.
«Imagine going forward [that] you might want to
build a
cell that not only told you it was exposed to something but it could tell you
how much or when.»
It involves the way an egg
cell is
built and
how information positioned during that construction affects the fate of the embryo.
The research also showed
how genetic mutations
build up in the cancer as it develops over time, as the leftover cancer
cells grow and spread.
Working with Bhaduri, who has a background in statistics and bioinformatics, Pollen and Nowakowski began exploring
how specific classes of neurons and stem
cells in the developing brain contribute to normal brain growth as well as to neurodevelopmental disease, and have begun to
build a comprehensive, open - source atlas of gene expression across the developing brain, which they hope will serve as a resource for other scientists.
«This information yields new insights into
how sperm stem
cells function and develop under normal circumstances,» says the study's lead author Bradley Cairns, PhD, senior director of basic science at HCI and professor and chair of oncological sciences at the U of U. «We have
built a very important framework we can now use to help us understand what happens when things go wrong, resulting in issues like infertility and cancer in men.»
A study led by Dr. Nicholas Harmer, Senior Lecturer in Structural Biochemistry at the University of Exeter, published today in the journal Chemistry and Biology, provides new information about the way bacterial
cells build up a defensive sugar coating and
how that process can be interrupted.
Previous work by Kolomeisky and his students showed
how microtubules are continually
built, destroyed and rebuilt by
cells that reuse the molecular
building blocks like Legos.
But viral immunologist Michael Farzan of the Scripps Research Institute in Jupiter, Florida, and 33 co-workers have recently taken a different strategy,
building a novel molecule based on our knowledge of
how HIV infects
cells.
Knowing the origin of each
cell and which genes control their normal function are the foundations for scientists to decipher the disease process and eventually to find out
how to guide the
cells to self - repair or even to
build up a brand new organ using amended
cells from the patients.»
The team identified chemicals released by bacteria that tell a new pair of lungs when to
build immune
cells,
how many to make, and when to use them.
The researchers gathered single
cells of warnowiids off the coasts of B.C. and Japan, sequenced their genomes, and analyzed
how the eyes are
built using new methods in electron microscopy that allow the reconstruction of three dimensional structures at the subcellular level.
In their March publication in Scientific Reports, researchers at Max Planck Florida Institute for Neuroscience and Kanazawa University describe
how they have
built the new AFM system optimized for live -
cell imaging.
Building on this research, investigators are trying to unravel
how vitamin D may protect
cells in the colon and the microbial composition of the bacteria, fungi, protozoa and viruses that live on and inside the human body, Moss noted.
But studying these genes, many of which play roles in brain
cell development, may ultimately help scientists understand
how intelligence is
built into brains.
Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by
how much messenger RNA — the gene's instruction guide that tells a taste
cell to
build a specific receptor — their taste
cells make.
«We started at the mTORC1 kinase and are
building the pathway up piece by piece to identify who is talking to whom in the pathway and to understand
how each of those proteins is relaying information about the availability of nutrients in the
cell.»
The field of single -
cell sequencing is rapidly expanding, with the potential to precisely study
how the basic
building blocks of life function and evolve.
The team
built a high - throughput
cell - editing platform using a variant of CRISPR / Cas9 technology that allowed them to test
how well scores of different genetic tweaks defended immune
cells against HIV.
Cardiologists have well - developed ideas for
how plaque rupture works *; see the concept of â $ œvulnerable plaque.â $ Cholesterol and inflammatory
cells build up in the coronary arteries over several years.
They are also resistant to the viruses researchers use in other
cell types to deliver DNA instructions about
how to
build the machinery needed for CRISPR / Cas9 gene editing.