More broadly, this landmark discovery has illuminated an unexplored avenue in scientists» understanding of
how cells control gene expression, and will indubitably incite a fresh wave of innovation in this ever growing field.
«New view on
how cells control what comes in and out.»
The finding could reveal much about
how cells control gene activity, and also illuminate cancer, multiple sclerosis, and other diseases spurred by faulty gene expression.
Fresh insights into
how our cells control muscle development could aid understanding of muscular dystrophy and other inherited diseases.
«It takes about one hour for the virus to complete the process, but questions remain about
how the cells control this precision in timing.»
In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating
how the cell controls gene expression through the destruction of messenger RNA.
Not exact matches
If we don't
control our
cells dividing, blood circulating, heart beating, bowel movements, breathing, etc., then
how is it that we can
control our destiny?
It's no secret that technology can help us stay organized and in
control — without our trusty
cell phones or tablets,
how would we check social media, know our bank balance, and respond to emails at a moment's notice?
She and her colleagues knew that chromatin regulators — which
control how genetic material gains access to a
cell's transcriptional machinery — were key to treating the social deficits in ASD, but the challenge was to know
how to affect key risk factors at once.
RNA molecules can attach to particular DNA sequences to help
control how much protein these particular genes produce within a given time, and within a given
cell.
The scientists also discovered that the stem
cells released tiny packets of microRNA, bits of genetic material that
control how genes function.
«Computerized biology, or
how to
control a population of
cells with a computer.»
Dr Nachbur said faults in
how the NOD2 pathway was
controlled could enable the
cell to continue to cause inflammation long after the bacterial threat has passed, leading to chronic inflammatory diseases.
A protein called YAP1 was previously shown to contribute to the growth of lung cancer
cells; however, it was unknown
how YAP1
controls lung cancer growth and progression.
Now, a research team at Lund University in Sweden has uncovered a completely new mechanism that
controls how proteins are produced to direct stem
cell function.
«The key point here is that we can say something about
how the gene acts to influence this behavior — that is, is by functioning as a chemical messenger in
cells that
control this behavior in the brain.
«If we learn
how to
control dendritic
cells, we could strengthen our immune response to infection when needed, or weaken the action of certain immune
cells that attack the body's own tissues in autoimmune disease.»
«We also study
how to
control living muscle tissue by electrical stimulation of the
cell,» he says.
Q1s create the pore that the potassium flows through and the E1s
control how slowly that pore opens and closes,
how many channels are on the
cell surface of each
cell and
how they are regulated by drugs.
By tweaking different fly genes and counting
how many neuron types were produced as the flies matured, the team identified a network of five genes that work together like coordinated
control switches to guide the precursor
cells» transformation to mature neurons.
Researchers know that shape is determined by the
cell wall, yet little is known about
how bacteria monitor and
control it.
By
controlling how the
cells assemble, the researchers engineered films that carry out a wide range of motor functions.
The discovery of a new mechanism that
controls the way nerve
cells in the brain communicate with each other to regulate our learning and long - term memory could have major benefits to understanding
how the brain works and what goes wrong in neurodegenerative disorders such as epilepsy and dementia.
Although the researchers don't know precisely
how the chaperone molecule works, the difference was unmistakable: Less than 40 % of
cells treated with gene therapy had clumps, compared to 70 % of
controls.
The newly unmasked genes play a role in three distinctively different bodily functions, including systems that
control inflammation and cholesterol and the regulation of
how brain
cells clean up toxic proteins.
Now, Johns Hopkins scientists report direct evidence in mice for
how those
cell clusters
control sleep and relay light cues about night and day throughout the body.
Researchers are using the sea hare model to learn about individual
cells function, discover the chemical pathways
controlling various brain activities and to study
how memories are processed and stored.
Biotech's latest mantra is «proteomics,» as it focuses on
how dynamic networks of human proteins
control cells and tissues
One describes
how proteins are made, and the other instructs the
cell on
how genes are
controlled.
It seems to
control how many times
cells in the cerebral cortex can divide, which
controls how much space there is for neurons.
They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the
control of stiffness alone, as well as investigate
how dynamic changes in matrix properties — a hallmark of the stem
cell niche — can be mimicked in the laboratory.
In their efforts to conquer the aging process, researchers are zeroing in on one specific part of the
cell: mitochondria, the energy - generating organelles that
control our metabolism and, it seems, help regulate
how long we live.
mTOR
controls a process that determines
how large our
cells are and
how many
cells we have.
A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet
control how it operates confer survival advantages on subsets of pancreatic cancer
cells.
Fisher's goal was to understand
how to strike down the skin
cells called melanocytes when they inexplicably go out of
control and cause melanoma.
The team's next step is to zoom in on the molecular mechanisms that
control how the Wnt signaling pathway interacts with the nail stem
cells to influence bone and nail growth.
But while this study has proved that the technique works in a simple organism, it could also be applied to other bacterial species, yeast or even human
cells to find useful information about
how genes are
controlled and
how they can be manipulated.
By examining the
cell cultivation dishes, the researchers were able to observe
how the patients»
cells behaved and developed from stem
cells to nerve
cells and compare them with
cells from healthy
controls.
Scientists at Columbia's Zuckerman Institute have uncovered new insights into
how stem
cells transform into brain
cells that
control leg movements.
Still unclear is
how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that
controls how well
cells resist or repair these stresses.
Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat
cells helps regulate
how glucose (blood sugar) is
controlled and metabolized (used for energy) in the liver.
It plays an important role in
how cells sense their neighbors and, by
controlling gene expression, determines which
cells should develop into different types and
how much they should grow - like a master controller.»
However, some experts warn that it's far from clear
how many holders of existing hES
cell lines will be willing to relinquish even partial
control of one of biomedicine's hottest commodities.
Further studies showed that very similar genes
controlled the process in animal and human
cells, and also helped piece together
how the genes work together to keep the
cell's recycling centers running.
In prior, unrelated experiments, the same species of worm had become hypersensitive to smell when its nerve
cells experienced problems with dopamine signaling, a cellular process that helps
control how readily
cells can communicate with one another.
This result reflected earlier findings that ILC and T
cell subclasses produce similar sets of cytokines, but also revealed differences in
how the two
cell types
control the activities of these key immune response genes.
The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO)
Cell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing ce
Cell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications,
how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the
control of
cell division — prevents cellular proliferation of rapidly dividing ce
cell division — prevents cellular proliferation of rapidly dividing
cells.
The last area is tools for analyzing the
cell, understanding
how to
control it.
Working with mouse embryonic stem
cells (mESCs), scientists at the IBS Center for RNA Research have come one step closer to understand
how to
control induced pluripotent stem
cells.
Lieberman, Dotiwala and their team were particularly struck by
how much the granzyme - sparked cascade resembles apoptosis, a
controlled form of cellular suicide that helps eliminate damaged or potentially cancerous
cells.