They play critical roles in
how cells of these organisms grow and divide.
Not exact matches
Essentially the model reproduces the inner workings
of all
of the proteins within the
organism and allows scientists to see everything from
how cells interact with each other to the functions
of genes in a larger context that had not been previously understood.
All an evolutionary storyteller has to do is to start with the apparently simplest version, ignore the neural equipment that has to be present for an
organism to make any use
of a «photon receptor,» and spin a charming tale about
how a tiny primitive light - sensing
cell might grow up to be a full - fledged eye.
As the very title
of the essay makes clear, his problematic is
how to justify the existence
of compound individual entities (e.g.,
organisms) when the ultimate entities are microscopic (
cells) or submicroscopic (atoms).
The second question has in fact two facets: (a)
how does it arise in the development
of the individual
organism during the process
of growth from the moment
of fertilization
of the egg; and (b)
how does the egg itself come to get that way — that is to say,
how can we conceive
of evolution as having «designed» the
cell?
I won't ever understand
how people could actually believe that something so massive, complex, and beautiful was actually started by some magical chance
of a random explosion, and that humans somehow evolved from some small
celled organism that happened to be created out
of the explosion.
Our evolution from a singular
celled organism due the inward placed orders
of the submicrocosmological being subjected beforehand; is but an under the unknowable considerations regarding the whys and
hows of cellular cosmologies tenured coming
of age.
The fact that
cells degenerate, that
organisms decay, that our own lives ebb toward death, that civilizations eventually fall and that noble deeds and ideals fade into oblivion — all this makes us wonder
how the universe could conceivably have any abiding seal
of purpose.
The Theory
of Evolution only talks about
how life evolved from the first single
celled organism up till what we have today.
The fields within biology are further divided based on the scale at which
organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry
of life; molecular biology studies the complex interactions
of systems
of biological molecules; cellular biology examines the basic building block
of all life, the
cell; physiology examines the physical and chemical functions
of the tissues and organ systems
of an
organism; and ecology examines
how various
organisms interrelate.
Her interest was piqued: Upon graduating in 1999 she joined the lab
of Ding Xue at the University
of Colorado, Boulder, to study
how cell death is regulated in the model
organism Caenorhabditis elegans.
How colonies
of single
cells evolved into multicellular
organisms has long been a puzzle.
The sea sponge may seem like an odd choice for genomic research considering that its simple body lacks muscles, organs, and nerve
cells, but the creature provides a wealth
of information on
how multicellular
organism arose.
The film depicts several sperm attempting to fertilize the egg, «zooms in» on one sperm's tail to show
how the dynein proteins move in sync to cause the tail to bend and flex, and ends with the sperm's successful journey into the egg and the initiation
of cell division that will ultimately create a new
organism.
«Understanding the role
of «noisy» fluctuations can help us understand
how bacteria diversify to survive,» Elowitz says, «as well as
how cells specialize to build multicellular
organisms.»
If this environment is harmed by chemicals, such as through damage to gut
cells, it could impact the health
of the
organisms and would lead to a number
of fish diseases but this technique will enable us to increase the tests we can carry out and improve our understanding
of how to preserve gut health.»
Using computational data analysis, Hughes hopes to create evolutionary trees
of these genes and regulatory mechanisms in order to figure out
how they work together to make
cells function and
how they contribute to the physiology
of the
organisms they are found in.
In neurons, ions flowing through the
cell wall initiate action, setting off a string
of communications that tell
organisms like us
how to feel and behave.
Collins said that because Hydra is such a simple animal and because it is able to regenerate after complete dissociation into individual
cells, it offers researchers the opportunity to use similar techniques as the ones employed in their experiments to examine
how an
organism develops from an unstructured group
of cells into a complex body plan.
Using machine learning, Chris Wiggins hopes to develop models that can predict
how all
of an
organism's genes behave under any circumstance - and thereby explain precisely why some
cells become sick or cancerous
Though little is known about Loki, scientists hope that it will help to resolve one
of biology's biggest mysteries:
how life transformed from simple single -
celled organisms to the menagerie
of complex life known as eukaryotes — a category that includes everything from yeast to azaleas to elephants.
Understanding this process - which is particularly important when
cells are first taking on specialized identities such as nerve
cells, muscle, skin, and so on - helps explain
how complex
organisms can arise from a finite number
of genes.
At that time, little was known about the molecular biology
of development —
how what's going on in the development process itself influences what can happen to the evolutionary trajectory
of cells and
organisms.
Darwin wrote about
how evolution shapes the destiny
of whole
organisms, but its principles apply to individual
cells, too.
Apart from advancing our understanding
of how plants regulate their growth and shape, this research presents new questions for stem
cell researchers in regards to
cell size checkpoints and their importance during
organism development.
How does an egg, a tiny squishy blob
of a
cell, grow into a fully formed
organism — a sinuous worm, a delicate fly, a perfect human baby?
In collaboration with the team
of Eduard Sabidó at the Proteomics Unit
of the Centre for Genomic Regulation and Universitat Pompeu Fabra, the researchers analyzed the proteins in Capsaspora to determine
how the
organism might be regulating its internal
cell processes at different life stages.
In addition, they also counted the numbers
of various types
of single -
celled organisms called testate amoebae, whose population changes depending on the amount
of water in the bog, giving an indication
of how wet or dry the climate was during different periods.
How does a single -
celled organism, one
of the simplest life forms on Earth, manage to satisfy its nutritional needs?
The team modelled
how the membrane changed, enabling LUCA's descendants to move to new, more challenging environments and evolve into two distinct types
of single -
celled organism, bacteria and archaea, creating the deepest branch
of the tree
of life.
There's a lot
of attention right now on
how neurons fire and interact with each other, but the truth is, we don't even understand
how a brain develops — even in the most simple
of organisms like C. elegans, a worm with only 300 brain
cells.
«The idea
of how organisms and their
cells evolve is still a big burning question.»
But
how an
organism is able to create such a diversity
of cells from the same genetic template and
how it manages to relocate them to wherever they are needed in the body is still largely unknown.
Craig Venter and his teams at the J. Craig Venter Institute in Rockville, Maryland, and San Diego, California, have shown themselves to be technical wizards by synthesising a genome from code contained on a computer, and using it to start a
cell line
of the resulting synthetic
organism (see «
How the synthetic bacterium was made»).
«
Cell death has been widely studied but much less is known about death
of whole
organisms,
how it happens, what triggers it, and when it begins and ends.
According to Greenberg, BRCC36 - KIAA0157 is just one
of many deubiquitinating enzyme complexes present in
cells of complex
organisms: «It turns out to be a general mechanism
of how this class
of deubiquitinating enzymes works.»
«I work on understanding
how cells «eat» using machinery based on vesicular carriers, and all my life I've dreamed
of seeing this in a live
organism,» Tomas Kirchhausen, Ph.D., a professor
of cell biology at Harvard Medical School and one
of the paper's authors, said in a statement on Thursday.
Caltech biologists work to reveal nature's mechanisms —
how tens
of thousands
of components act in concert in
cells,
how organisms grow from single
cells,
how the brain maintains its consciousness, emotions, and superb computational capabilities, and what happens when any
of those processes goes awry.
I didn't groan at this idea unlike most other Star Wars fans — many
of whom were outraged by the perceived reduction
of the Force from a grand, almost magical power to a function
of biology — because I'm a biologist who studies bioenergetics:
How organisms convert various molecules (food) into chemical energy (adenosine triphosphate or ATP, a compound that enables energy transfer between
cells) that can be used to power life.
Organisms differ in ploidy, or
how many copies
of the genome they carry in their
cells.
Understanding
how organisms grow from one
cell type to many different
cell types is the overall goal
of lineage tracing or fate mapping experiments, the first
of which date to the late 19th century.
«It's really interesting to be embedded within the context
of the Thomson lab and in the whole stem
cell milieu, and understanding
how this axolotl might be employing the same pathways that are present in other
organisms — and possibly people,» Nelson says.
Experimental evolution is a good way to enhance our current understanding
of how genomes — or sets
of chromosomes in an
organism's
cells — evolve and the role
of individual mutations in adaptation.
The findings help explain
how axons, the long projections
of nerve
cells, grow toward and across an
organism's midline whether in the mammalian spinal cord or its equivalent structure in flies and...
By studying the planarian we hope to understand
how stem
cells are regulated to produce missing tissues and organs in the context
of a whole
organism.
Thus, given its deep history in understanding
how organisms counter infection, LJI is well prepared to lead the charge against inflammatory disease, because often the same
cells that rid us
of infection are the ones that destroy healthy tissue in inflammatory or autoimmune disease.
This is a reflection
of how extremely difficult it is to understand the complex functions
of a three - dimensional
organism with its many different
cell types and substances without animal research.
The grand prize
of USD 25,000 goes to Liron Bar - Peled for his work describing
how multicellular
organisms rely on environmental cues to dictate
cell size.
New approaches to microscopy, precision laser ablation
of individual
cells and capillaries, and genetic engineering
of model
organisms are opening new vistas for exploring the brain and
how it works.
All this leads to the question
of how confident you can be that in the period when sex is being determined, the threshold number
of XY
cells required for sex / testis determination were truly absent in those putative XO
organisms?