Sentences with phrase «how cells repair»

Sung's expertise is in how cells repair double - stranded breaks in DNA.

This new function for GFI1 is a new piece of the puzzle to understand how cells repair their DNA.

Their technique has shed light on how cells repair DNA strand breaks, which could help scientists learn how to protect astronauts from cosmic rays as well as refine radiotherapy protocols designed to kill tumors.

Berkeley Lab scientists are using a similar approach to study how cells repair DNA damage.

«Although we are investigating a very basic problem in biology — how cells repair DNA damage — our discoveries have potential ramifications in the clinic,» says de Lange.

«Mice engineered with rare kidney disease shed light on how cells repair broken DNA.»

Agata Smogorzewska, head of the Laboratory of Genome Maintenance, wants to understand how cells repair interstrand cross-links, a particular type of DNA damage in which the two strands of the double helix that normally twine about each other become physically linked.

Not exact matches

Still, researchers now have a far better understanding of the molecular pathways in the ear and how to regenerate hair cells and repair synaptic connections.

I'm reminded of something that happened to me recently concerning tinnitus.A fellow worker and I were discussing cell phones and he was telling me how he had hoped that the recent repair for his cracked phone case wd also solve the ringing that he hears when using it.

This app create a great interactive learning experience: How do cells divide to grow new hair, repair skin, or strengthen bones?

One of the key questions in biology is to identify how tissues are repaired after trauma and understand how stem cells migrate, proliferate, and differentiate to repair tissue damage.

Published in Molecular Neurobiology, the study led by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in Stem Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cCells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cellscells.

«It will be exciting to explore how cell culture conditions enhance the zygote's intrinsic surveillance and repair mechanisms, thus leading to better quality embryos and potentially more successful pregnancies.»

Ever wondered how a molecular nanomotor works when repairing DNA or transporting material such as organelles in the cell?

«It's possible that some of these same mechanisms that we've seen in yeast may be influencing the amount of damage that is forming and how quickly it is repaired in human cells,» he said.

First, they determined how repair proteins failed to recognize and act on chromosome breaks during cell division.

A major concern of the CRISPR - Cas9 approach, in which the double - stranded DNA molecule is cut, is how the cell responds to that cut and how it is repaired.

All of these findings were supplemented with several other experiments that were designed to learn how CHI3L1 interacts with other cells involved in the tissue repair response in both human and mouse lungs.

Still unclear is how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that controls how well cells resist or repair these stresses.

Twenty - five years from now, our kids will only know some diseases, such as osteoporosis, from old books, and by then we will probably know how to repair tissues with stem cells.

So if biologists can discover how to disable cancer cells» DNA repair proteins, it may be possible to destroy tumours using lower doses of radiation or drugs.

Researchers don't know exactly how the stem cells work, but they assume they are performing nerve repair.

Now, Strahl's team found that Set2 also regulates how the broken strands of DNA — the most severe form of DNA damage in cells — are repaired.

Understanding how networks of cells in circuits work together to give rise to behaviors, thoughts, and emotions requires new technology, he said, and optogenetics is starting to provide new approaches for mapping and repairing the brain.

«We found that Set2 is required when cells decide how to repair the break in DNA,» said Jha, the first author of the Nature Communications paper.

«Tiny heart, big promise: Understanding how cells become coronary vessels may lead to advances in repairing heart damage.»

The new technology, developed by Salk scientists and published in Neuron, is helping researchers understand how spinal cord cells make connections with motor neurons, and how clinicians might be able to repair those connections in patients with spinal cord injuries or neurodegenerative diseases like amyotrophic lateral sclerosis (ALS).

«Stem cells have an innate ability to repair and regenerate, and that is how the baby's condition improved,» says Titus.

Last week, Lin Zhang, MD, an associate professor of Obstetrics and Gynecology, described in Science Translational Medicine, how his team treated therapy resistant cancer cells to renew their sensitivity to PARP inhibitors, a class of drugs that, when effective, prevent cancer cells from keeping up with DNA repair, causing them to eventually die.

«How cells adapt to help repair damage: Genetic processes that allow cells to transform so they can mend damaged nerves have been identified by scientists.»

Therefore, there is an urgent need to understand what happens to the cells during disease and how can they be repaired,» said researcher Yan Hu, PhD.

Knowing the origin of each cell and which genes control their normal function are the foundations for scientists to decipher the disease process and eventually to find out how to guide the cells to self - repair or even to build up a brand new organ using amended cells from the patients.»

Then they analyzed all the cells in the early embryos at single - cell resolution to see how effectively the mutation was repaired.

«Hail Mary» mechanism can rescue cells with severely damaged chromosomes: Understanding the mechanisms involved in chromosome repair, and how they can fail, may lead to new strategies to combat cancer.»

«One unmet need in regenerative medicine is how to effectively and safely mobilize and guide stem cells to migrate to lesion sites for repair,» Zhao said.

Scientists now have a good idea of how cells» repair kits work and the roles they play in other processes such as aging.

There, the researchers observed how the cell was able to repair the defects with amazing perfection in some regions, but not in others.

Contact: 508-685-3525; [email protected] WOODS HOLE, Mass. — How do cells move in a certain direction in the body — go to a wound site and repair it, for example, or hunt down infectious bacteria and kill it?

Future studies can now address how to maintain induced retinal cell cultures in a proliferative, multipotent state and drive them to all the retinal cell classes necessary to repair a damaged or degenerating mature retina.

Given the ability of cells in the body to participate in repair, it is imperative to understand how to harness such a property at will.

He studies how structural changes to chromosomes impact gene expression and cell fate with a focus telomere, telomerase, and chromosomal stability, epigenetic proteins, and the role of the SOSS complex in DNA damage repair.

In a paper published in the March 25, 2010 issue of Nature, researchers working at the Salk Institute for Biological Studies and the Center of Regenerative Medicine in Barcelona (CMRB) identified a fish heart cell population that is the source of this astonishing healing feat, a finding that could provide insight into how mammalian hearts might be coaxed into repairing themselves after injury brought on by heart attack.

That requires a third component: a DNA template strand to tell the cell's repair machinery how to fill in a cut made by Cas9.

Find out how scientists are using stem cells to attempt to repair the neuronal highways that are damaged in multiple...

By figuring out how frogs regenerate tissue, Tseng hopes she and other scientists can learn how to get stem cells to better repair or regrow tissue in humans.

He originally became interested in looking at how the immune system might be involved in regeneration because as a «first responder» when someone is injured, macrophages would be the cells responsible for «preparing the ground for tissue repairs.»

Deepak Srivastava writes about how by helping cells switch their type, we may have discovered a new way to repair damaged hearts, and potentially revolutionize the future of medicine.

I firmly believe that basic knowledge is absolutely necessary; if we are going to be able to repair injured retinas, we need to know how different retinal cells are made normally, so we can remake them in a culture dish and use them to replace injured retinal cells.

2010 — We discover how a gene that normally plays a role in nerve cell repair can also help some nerve cancers spread.

Here we address how polarized enterocytes harboring actin - rich apical microvilli undergo extensive cell remodeling to drive injury repair.