The question of
how cellular behavior is controlled is at the center of stem cell biology, and understanding the mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.
Not exact matches
So in 1974, he headed south to Tulane University in New Orleans, Louisiana, for graduate training in physiological psychology: the study of
how the brain influences
behavior at the neurochemical and
cellular levels.
The sea slug was the model organism for Kreiner's thesis research, which explored
how cellular mechanisms mediate simple
behaviors and led to a publication in Science.
In the past decade, researchers have used mouse models to unravel
how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related
behavior.
Manipulating biological processes with minimal interference, from the
cellular level to the
behavior of whole organisms, is a burgeoning scientific effort to better understand
how living things work and to develop more effective treatments for a range of medical disorders.
Neuroscience can range from studying psychology or
behavior to investigating
how the nervous system functions at a
cellular or molecular level.
Although some of the key molecular components involved in the formation of
cellular structures and tissue formation are known, we currently lack a bottoms up understanding of
how the
behavior of these molecules gives rise to the formation of large structures, partly because of the lack of tools for both studying the spatial regulation of soluble proteins and biophysically characterizing the
behavior of large structures and tissues.
Swedish - born Sten Griller has defined the principles that govern at the
cellular level
how nerve circuits that control vertebrate motor
behaviors work.
By comparing the regulatory networks of pathologic conditions, I expect to gain new insights into the central question:
how do regulatory networks instruct
cellular behavior under diseased condition and can we discover drugs that can alter these regulatory networks.
Beyond the internal interactions of the protein itself, these designed oligomers can be used to explore basic questions about
how the structure of signaling molecules affects the
behavior of receptors and
cellular response.
identify molecular,
cellular, and anatomical similarities in
how these molecules work across species that represent the fundamental principles through which brain neurochemistry affects social
behavior in vertebrates.
«Our ongoing project aims to elucidate
how cells recognize temperature or
cellular events caused by the temperature changes and control the expression of DESAT1 to adapt the
cellular processes and
behaviors,» Umeda said.
«Vertical integration of gene function» describes
how gene expression initiates a series of biochemical,
cellular, and physiological changes that ultimately culminate in an observable
behavior.