Sentences with phrase «how cellular changes»

In the past decade, researchers have used mouse models to unravel how cellular changes in the nucleus accumbens (NAc), a brain structure involved in action selection associated with arousal and reward, may contribute to addiction - related behavior.

Not exact matches

Flamingos change color based on their diet and how can we truly understand all of the dynamics at a cellular level to cause a mutation in a bacterium?

Their work also revealed how tensegrity - based changes in molecular shape can drive the motion of cellular parts.

«This is the first study, to our knowledge, that demonstrates the mechanical continuity, strain transfer, and conformational changes that result from chemical energy release from the atomic scale up through the whole - cell level, as well as how tensegrity guides those changes to drive cellular movement,» says Ingber.

They used this novel simulation approach to build a model of a sperm cell that demonstrates cellular movement from individual dynein protein molecules in the tail all the way up to the whole cell, allowing them to observe how changes at the atomic level are reflected in larger - scale structures.

Changing how the RNA folds can serve as a control knob in cellular processes — increasing, decreasing or altering activity in specific pathways — but determining how to make RNA so it folds in a particular way has long been a tedious and arduous process.

They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the control of stiffness alone, as well as investigate how dynamic changes in matrix properties — a hallmark of the stem cell niche — can be mimicked in the laboratory.

To find out why, computational biologists came up with a computer model to predict how microbial metabolism and cellular composition change as cell size varies, using details about how much space a bacterium needs for its components — DNA, proteins, and the molecular factories called ribosomes — to function.

The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»

«While several lipid families are well - characterized at the molecular level, the total diversity and number of unique lipids in cells, how they change during cellular activation, and how they differ in individuals is unknown,» said Darley - Usmar.

At a cellular and molecular level, no one really knows how the vagus nerve detects different physiological stimuli, from the stretch of the stomach after a meal to toxins that induce nausea to changes in blood pressure.

The aim of the team was to gain insights in to the molecular features of totipotency and to work out how changes in cellular plasticity may occur.

A critical next step for this work is to understand how senescent changes in late life trigger such destructive waves of cellular necrosis.

«We now have a tool to control temperature on a cellular level, and we can study how biological systems react to temperature change,» says Peter Maurer, a physicist at Harvard University in Cambridge, Massachusetts, and a member of the team publishing the result today in Nature.

Now one team, reporting in the journal ACS Chemical Neuroscience, has identified how amyloid beta, the protein fragment strongly associated with Alzheimer's disease, can induce cellular changes that might lead to Parkinson's.

Dr. Chartoff is interested in how chronic exposure to drugs of abuse changes the brain at molecular and cellular levels such that drug withdrawal elicits a protracted constellation of negative affective signs.

The aims of the CEMC are to define the step-wise molecular and cellular alterations that occur during the process of carcinogenesis; determine how environmental exposures cause key genetic mutations and epigenetic changes that underlie carcinogenesis; and discover the impact of environmental factors on the generation and maintenance of cancer stem cells.

The CCP is engaged in numerous multidisciplinary projects in other model systems (e.g. fly, zebrafish, yeast) that aim to determine how complex molecular circuits function and evolve in response to genetic and environmental changes, cellular differentiation, evolution and disease.

A second line of research is to use skeletal muscle formation in the chick embryo as a model to understand how cells within tissues display complex behaviours while being exposed to an ever - changing cellular environment.

In 2016, the Food and Drug Administration (FDA), the branch of government charged with regulating cellular therapies, took action to address these issues, proposing revised guidelines that could change how stem cells, especially autologous stem cells, are regulated.

Studies at the cellular level help us to understand how the gene products involved in learning and memory mediate physiological changes in the neurons that encode memories.

«Our ongoing project aims to elucidate how cells recognize temperature or cellular events caused by the temperature changes and control the expression of DESAT1 to adapt the cellular processes and behaviors,» Umeda said.

The aim: learn how changes in gravity levels affect the heart not just as an organ, but on the cellular level.

«Vertical integration of gene function» describes how gene expression initiates a series of biochemical, cellular, and physiological changes that ultimately culminate in an observable behavior.

How do changes on a cellular level contribute to adaptation processes that allow the brain (and with it its owner) to age successfully?

In the study, the researchers describe the microscopic physical interactions and chemical changes of proteins associated with several cellular functions, including disease forms, and how still - healthy cells could try to temper it.

It's also not entirely clear how much these cellular changes really affect healthy people without elevated inflammation.

And while how much of it might not be the only consideration — the strange, changed cellular structure may cause the body to react — it appears that even hybridization may not explain the entire problem with wheat products the way Americans are eating them.

The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a specific health issue even though they have a SNP mutation.

Just by making specific changes the what, when and how you eat, can take the load off the body and allow more cellular energy to be spent on things like cell turn over, repair and detoxification.

You'll learn practical ways to apply this science immediately through the MELT Hand and Foot Treatments — and how these simple self - treatments can improve your body's ability to restore balance and support cellular repair and regulation, which can create remarkable, lasting changes in just a few minutes a day.

Molecular medicine and molecular biochemistry provide the what and how these changes, especially deleterious ones may be treated, cured, suppressed, or understood in context with other gene regulatory mechanisms and transcription and translation coupled systems within the actual cellular environment.

Along with these two bigger changes, Android Wear 2.6 also introduces the ability to see Wi - Fi, Bluetooth, and cellular icons in your Quick Settings page, the size of text for notifications now changes based on how much is being shown on the screen at once, and there are also fixes to accidental swipes and gestures that some users were previously complaining about.

For all those inexperienced persons who don't know easy tricks on how to set up most up - to - date Android O eight.Zero into their gadgets, they'll with out considerations download and set up Android Oreo eight.Zero launcher that can change into your cellular into android 7.1 UI.