Sentences with phrase «how effective our drug»

For now, the question is how effective the drug will be in animals other than mice.

A popular approach is to measure how effective a drug is in helping rats and mice learn their way around mazes.

The perfect system: Where medicine travels and where it ends up in the body directly influence how effective the drug will be in easing pain or curing disease.

She's looking at the gut microbiome and how it might influence how effective a drug is or how safe it is.

To do this, we have to estimate how effective our drug would be.

Put that together and you've got a problem: Pharma trials assume that placebos act independently of medications, which is why sugar pills are pitted against drugs to measure how effective the drugs are.

Through the clinical trial, veterinary researchers can assess how effective the drug is in extending the dogs» lives and how long it takes for them to develop resistance, and translate those results to humans.

Not exact matches

So how can he argue that Nixon, who had fabricated this bogus drug war to deceive the American people, in fact had an effective drug policy which we should restore?

«The Sentencing Council's guideline brings sentencing guidance together for the first time to help ensure consistent and proportionate sentencing and provide effective guidance for sentencers and clear information for victims, witnesses and the public on how drug offenders are sentenced.»

A new study explains how a widely used drug is effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues.

«Understanding the fundamental biology of how our immune system works will lead to the development of more effective drugs and vaccines,» said Kanneganti, corresponding author on the paper.

The research team currently is working to identify new biomarkers that will allow them to develop a better understanding of how drug resistance develops, and how to best design effective combinations of medications that may improve patient responses.

Researchers have new insights into how protective antibodies attack dengue viruses, which could lead to more effective dengue fever vaccines and drug therapies.

«Using this technology, the study is the first to discover the critical role of astroglial cells in Down syndrome as well as identify a promising pathway for exploring how a drug such as minocycline may offer an effective way to help treat it.»

The new paper also provides the first detailed explanation of how the scientists created a mathematical formula that can help predict which combinations of drugs will be most effective.

Understand how electrons move, and we might control reactions better, design more effective drugs and better materials for generating energy, and boost today's sluggish computers to warp speed.

In another study, the same researchers who discovered the uptake of antibiotics by plants tested four of these drugs to determine how effective composting would be in reducing harmful chemicals in turkey manure.

«Given that marijuana is the most commonly used illicit drug by high school students in the U.S., having a better understanding of how marijuana use affects future SC use and vice versa is essential for designing effective prevention and intervention programs.»

The authors point to studies of harmful and beneficial effects of thrombolytic and antiarrhythmic drugs for myocardial infarction, for example: «Not only would systematic reviews... have reduced waste resulting from unjustified research, they would also have shown how to reduce morbidity and sometimes mortality, both in patients allocated to relatively less effective or actually harmful treatments in unnecessary trials, and in patients generally,» the authors write.

The other study showed how using a combination of drugs at increased potency could prove an effective therapy against glioblastoma by inhibiting the PI3K and MAPK cellular pathways.

This webinar will focus on how rewiring of signaling pathways in response to drug treatment contributes to resistance and how this knowledge can be leveraged to develop more effective treatment strategies.

Unfortunately, it is still not known exactly how the adopted drugs (which are effective in only about 45 percent of cases and come with an array of side effects) help migraines.

«Understanding how the disease works is important to developing effective drugs that protect the brain and stop the progression of PD,» said Pahan.

In the Cancer Cell article, the researchers describe how various anticancer drugs, including cisplatin and the targeted therapy vemurafenib, which targets melanomas with the BRAF mutation, become more effective when co-delivered with phenformin.

Participants were randomized into four different interventions that would analyze how effectively an acupuncture technique known as electroacupuncture — in which embedded needles deliver weak electrical currents — reduces incidents of hot flashes as compared to the epilepsy drug gabapentin, which was previously shown to be effective in reducing hot flashes for these patients.

«Our study on the TACC3 - chTOG interaction will allow cellular biologists and researchers on microtubule dynamics to better understand how microtubule assembly is regulated during cellular division,» says Montoya, and he anticipates that «it could also help in developing new anti-microtubule drugs, providing more effective therapeutic options in cancer treatment.»

Discouraged by recent findings that antiviral drugs such as zidovudine (AZT), ddI and ddC are less effective than had been hoped, many people with HIV, and their doctors, are now confused about how and when to use them.

The findings open up new avenues of research into exactly how the brain controls eating, and suggest that drugs designed to activate or inhibit neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as diabetes and hypertension.

Scientists do not yet fully understand how antibiotics work on the molecular level, but they think that the drugs are effective in part by introducing reactive oxygen to bacterial cells, which damages key cellular structures.

Last week, Lin Zhang, MD, an associate professor of Obstetrics and Gynecology, described in Science Translational Medicine, how his team treated therapy resistant cancer cells to renew their sensitivity to PARP inhibitors, a class of drugs that, when effective, prevent cancer cells from keeping up with DNA repair, causing them to eventually die.

But ultimately, he says, Scripps's stability will be decided on how effective Schultz and Kay are in hooking together formerly disparate parts of the drug development pipeline, and how many would - be drugs the fishing buddies manage to snare in their net.

Recently a series of drug recalls have pulled back the curtain to show how the media, the public, and some doctors can misinterpret medical studies or take them out of context in ways that make medical treatments look safer and more effective than they actually are.

Yet GPCRs» structures — key to understanding how they work and to designing more effective drugs — have remained relatively hidden from view.

Researchers at University of Florida Health have discovered the mechanics of how dopamine transports into and out of brain cells, a finding that could someday lead to more effective treatment of drug addictions and neurological disorders such as Parkinson's disease.

Discovering the structure of this enzyme will provide valuable insight into how this protein functions and could provide blueprints for designing drugs that inhibit or increase certain protein functions, which would make those drugs more effective.»

Our lack of knowledge into how antipsychotic drugs bind to their receptors has held back progress towards creating more effective medications.

Together the team will not only be able to provide clarity on which drugs are most effective against tumors with specific PI3K - pathway mutations, but how these specific mutations differentially affect how the pathway functions.

These research collaborations have the power to answer questions critical to improving cancer outcomes, such as how tumors develop drug resistance, and what treatments are most effective against particular genomic traits.

To address this growing problem, NIAID is funding and conducting research on many aspects of antimicrobial (drug) resistance, including basic research on how microbes develop resistance, development of new and faster diagnostics, and clinical trials designed to find new vaccines and treatments effective against drug - resistant microbes.

A better handle on the basic biology of intranasal oxytocin, such as how it enters the brain and which receptors it hits, might enable researchers to develop more effective drugs, Young adds.

He's tinkering with small interfering RNA to see how to make them more stable and effective as drugs.

The results of pre-clinical testing are also used to determine how to best formulate the drug for its intended clinical use, for example whether it would be most effective as a cream, a pill, an injection or a spray.

Knowing how ISRIB stabilizes elF2B may help Calico researchers and other collaborators tailor even more effective next - generation drugs against neurodegeneration and traumatic brain injury.

How else would he be effective at «coaching» high level amateur and professional athletes, most of whom use performance enhancing drugs during at least part of the year?

The news about how effective coconut oil is in treating Alzheimer's Disease is spreading fast, as the failure of drugs in treating Alzheimer's are widely documented in the mainstream media.

I have no experience with clients using this drug, how effective it may be and what side - effects folks may experience.

Newcastle University researchers analyzed eight studies that looked at how effective different weight - loss methods (diet, exercise, drugs) are for people with the FTO gene.

Keep in mind that when the FDA approves a drug, no one has to explain or demonstrate exactly how it works, only that it is statistically more effective than a placebo and that it doesn't come with significant health problems as a result of using it.

It's important to know that no matter how reassuring the doctor is on effective drug therapies, how minimally the infection has physically affected you or how emotionally and intellectually prepared you may be, you need the love and support of close family members or a companion.A close companion will help you lead a happy, positive and productive life.

As a thriller its quite nerve wracking and as a metaphor for how innocent Mexican citizens are used as pawns in the drug war between the various gangs and the DEA its effective.