Sentences with phrase «how essential those genes»

Not exact matches

The Hawaiian strain changed that thinking: «How is this wild isolate alive and happy without a gene that's supposed to be essential for development?»

These genes are believed to be essential for the normal function of nerve cells, and previous studies have linked these mutations to problems with synaptic function — how neurons communicate with each other.

Computer aided modeling of how the Bcl3 gene functions inside the cell allowed the group to identify a pocket on the surface of Bcl3 essential for its function.

Explaining the background to the research, Dr. Ramiro describes how «an essential process in antibody generation takes place in structures called germinal centers, where antibody genes undergo small modifications that increase the efficiency and specificity of the immune response.

But Ziv Bar - Joseph, an associate professor in the Machine Learning Department and the Lane Center for Computational Biology, said that view of what is essential and what isn't reflects how scientists study genes — by noting their effects on an organism when a gene is removed — not necessarily the gene's importance.

Because CRISPR will never fully be rid of off - target effects, the key question for a given therapy is not strictly how many unwanted cuts it makes, but whether it disrupts any essential genes, says Jiing - Kuan Yee, a molecular biologist at the research center City of Hope in Duarte, California.

They have learned how to turn on and off essential genes and how to transform embryonic stem cells into retinal cells, which can be transplanted into mice to restore vision.

Understanding how these effects are dependent on the post-mortem interval is essential for the proper use of post-mortem gene expression measures as a proxy for ante-mortem physiological gene expression levels5, 10,18,19,20.

In a study appearing online February 8 in advance of publication in the March issue of the Journal of Clinical Investigation, Gallo and his colleagues look at how the innate immune system is controlled in the skin, and find that genes controlled by active vitamin D3 play an essential role in the process.