It will also examine
how exosome secretion is linked to VSMC migration, proliferation and ECM remodelling and hence vascular pathology.
The molecular mechanism of
how the Exosome is regulated, however, is not very clear yet.
Researchers at the Bellvitge Biomedical Research Institute of Bellvitge, the Catalan Institute of Oncology and the University Hospital of Bellvitge have participated in an international study published in the journal Cancer Cell that describes
how exosomes secreted by tumor cells contain protein and microRNA molecules capable of transform neighboring cells into tumoral cells promoting tumor growth.
Not exact matches
How do the
exosomes get into the recipient cells?
The Lund researchers» discovery is the
exosomes» journey from the sender cell to the receiver cell and
how the receiver cell captures and internalizes the
exosomes.
«We identified
how CD47 contributes to suppressing
exosomes clearance from circulation, and enhancing their delivery to pancreatic cancer cells.»
Also covered will be techniques for analyzing
exosomes, microvesicles, and apoptotic bodies in unprocessed samples,
how imaging flow cytometry can be used to evaluate or reevaluate EV isolation techniques, and the advantages and disadvantages of using this method.
Kraig's team is now exploring
how to craft
exosomes into a treatment for multiple sclerosis.
The researchers also discovered
how to generate
exosomes outside the body, making them on demand for potential therapies.
«Understanding these characteristics may help scientists better understand
how exomeres and
exosomes help cancers grow and spread to other organs, as well as what role they may play in other diseases,» Dr. Zhang said.
In a new study, researchers use proteomic approaches to discover
how mesenchymal stem cells - derived
exosomes modulate angiogenesis
It was by studying the cells of patients with an RNA
exosome mutation, which were contributed by six collaborating medical centers, that the investigators were able to understand
how influenza A hijacks the RNA
exosome inside a cell's nucleus for its own purposes.
«The physician would propose a treatment plan and the amount of
exosomes in a follow - up urine sample would indicate
how effective the treatment was.»
The droplets, called
exosomes, contain genetic information that can be analyzed to determine a cancer's molecular composition, even
how far it has advanced.
A new Infection and Immunity report describes
how infected macrophages send signals to uninfected macrophages: via
exosomes.