Sentences with phrase «how gene expression changed»

The researchers used the worm's genomic information to study how gene expression changed during regeneration.

«We don't even know how gene expression changes on a day - to - day basis!»

RNA - seq technology offers a rapid and scalable approach to characterize how gene expression changes in response to experimental manipulations, and is applicable across a wide range of taxa.

We are also examining how gene expression changes caused by chromatin modifier mutations interact with other commonly mutated pathways in urothelial cancers such as RTK - RAS - RAF and PI3K - AKT - MTOR to influence therapeutic response and resistance.

Not exact matches

«It was a little eerie and a little scary to see how something as subtle as a nutritional change in the pregnant mother rat could have such a dramatic impact on the gene expression of the baby,» Jirtle says.

In a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expression.

However, very little is known about how the circadian clock regulates this critical part of gene expression to organize the day - night rhythm of protein expression, and if the formation of this looping changes over the day.

Finally, the team identified a network of genes in these regions that exhibit changes in expression when the normal boost from serotonin is lacking, and these changes depended on how long the drug was given.

According to the researchers, this is the first study to link the extreme and rapid eating - induced changes of the Burmese python's intestines directly to changes in gene expression, and also the first to show how quickly gene expression changed.

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changes.

The research draws from previous findings by molecular biology and genetics professor and study co-author Mariana Wolfner on how Drosophila females» gene expression, behavior and physiology are changed by mating.

The Plant Signaling investigation and Biological Research in Canisters (BRIC) 17 - 1 both study how the plants» gene expressions change in microgravity.

Following on from this discovery, the next fundamental question to answer is, how is this signal being transmitted from the chloroplast to the nucleus to change gene expression within the cell?

The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»

It's not clear how long the gene expression changes may last.

The emerging field of epigenetics explores how our lifestyle and environment can change gene expression, for example, by adhering molecules such as methyl groups to the DNA strand.

We predicted a link between gene expression evolution across species and the degree of sexual selection, but this is the first statistical evidence for it and shows how powerful sexual selection can be in leading to major changes in how a gene is expressed.»

The team analysed the sperm of the offspring from the undernourished mothers to see how many genes had had their expression altered by the addition or removal of a methyl group — an epigenetic change.

They found changes in gene expression that help explain how effective treatment leads to conversion of aggressor into protector cells.

Orbiting scientists are also studying bone loss, aging and gene expression and performing combustion experiments that show how flames change shape and how different fuel mixtures behave in space.

When studying how normal cells change into cancer cells, dos Santos and other cancer researchers pay close attention to gene expression.

This includes how subtle changes in gene sequences can impact the expression of encoded proteins through mechanisms including codon bias, mRNA stability, and translation initiation.

«Understanding which genes are involved in transgenerational acclimation, and how their expression is regulated, will improve our understanding of adaptive responses to rapid environmental change and help identify which species are most at risk from climate change and which species are more tolerant,» Dr Veilleux says.

The findings improve our understanding how changes in diet and gene expression affect the speed of aging.

A long - term goal of our research is to understand how neuronal activity elicits changes in gene expression that are important for learning and memory.

He studies how structural changes to chromosomes impact gene expression and cell fate with a focus telomere, telomerase, and chromosomal stability, epigenetic proteins, and the role of the SOSS complex in DNA damage repair.

We show, for the first time, the influence of the gene expression levels demonstrating the power of «big data» to change how medical research is performed.

Further investigation of those findings could lead to identification of the affected genes and how the expression changes contribute to the development of TS and OCD.

As they develop microscopy techniques to better visualise the details of chromatin structure, even in living cells, they're better able to explore how structural changes relate to gene expression and cell function.

By determining how changes in gene expression affect the fate of glial cells in mice, we hope to understand the key factors that govern neural cell regeneration in the human brain.

Nick Owens, a post doc in Mike Gilchrist's lab, who developed the computational analysis, said: «This study improves our ability to understand the way gene expression changes with time, and from this we gain insight into the logic of how gene expression is regulated.

However, researchers from the laboratories of Ralph Stadhouders, Marc A. Marti - Renom, and Thomas Graf have now applied a highly efficient and synchronous reprogramming system [2, 3] to study how genome topology, chromatin states, and gene expression dynamically change during reprogramming [4].

His discoveries include insights into how changes in gene expression affect T cell exhaustion, a waning of immune function that occurs in response to chronic viral infection and cancer.

In particular, the lab investigates how alterations in epigenetics — or the heritable changes that affects gene expression without alterations in the underlying DNA sequence — contribute to epithelial ovarian cancer.

«Vertical integration of gene function» describes how gene expression initiates a series of biochemical, cellular, and physiological changes that ultimately culminate in an observable behavior.

These findings provide new insights into how chromatin regulation modulates stochastic gene expression and transcriptional bursting, with implications for regulation of pluripotency and development.Polycomb repressive complexes modify histones but it is unclear how changes in chromatin states alter kinetics of transcription.

In the book Relaxation Revolution: The Science and Genetics of Mind Body Healing, author Herbert (Benson) discusses how breathing can literally change the expression of genes, and that by using your breath, you can alter the basic activity of your cells with your brain.

To know more about how genes are expressed and how changes and down - regulation in its expression affect its translation, watch this video.

It's the powerful new science of how nutrients in your food, drinks, and supplements may affect your health by changing the expression of your genes.

Norwich, England About Blog Nutrigenomics: Discover your genetic risks and how your dietary and lifestyle choices are changing your gene expression and future health potential.

These alterations can change genetic expression, or even switch genes off, and may be part of the explanation of how maltreatment affects the developing brain.

Epigenetics provides another way of understanding how genes and environment interact in that there is increasing evidence that gene expression is moderated by the environment in which the organism grows and develops.15 Genetic information is encoded not just in DNA linear sequences but in epigenetic changes in chromatin structure such as DNA methylation or covalent modifications of the DNA - binding proteins.