Sentences with phrase «how gene profiles»

He and his colleagues are now investigating how gene profiles are altered and whether these techniques could ease symptoms in people with high blood pressure, inflammatory bowel disease and multiple myeloma, a type of bone marrow cancer.

Not exact matches

Even before the company's novel gene - profiling tool was market - ready, even before they knew how to outflank a long - established competitor (Affymetrix), Stuelpnagel was looking far into the future.
To illustrate how it works in practice, Koenig offers the example of a professional hockey player whose profile shows that he has gene variants found in people who respond rapidly to lactic - acid threshold training.
Based on how the genes fit within the original, mapped profile, they can predict with a high accuracy if a particular patient will develop metastatic tumors.
Pharmacogenomics — the study of how genes affect responses to drugs — is becoming more important in drug - development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.
Howard Hughes Medical Institute (HHMI) scientists have profiled key features of the genetic material inside three types of brain cells and found vast differences in the patterns of chemical modifications that affect how the genes in each type of neuron are regulated.
Rao's team used various approaches, including assays of telomerase activity, measurement of cell growth, and gene expression profiling of TSY - 1 treated cells, to determine how it acts.
The assay can be used to create a «molecular profile» that reveals the presence of a gene and how much RNA and protein it has expressed all from the same sample — something that now requires three more complicated techniques.
Gene expression profiling tests, such as Oncotype Dx, analyze the patterns of 21 different genes within cancer cells to help predict how likely it is that a women's cancer will recur within 10 years after initial treatment and how beneficial chemotherapy will be to her.
Modality of access under this proposal: Users will provide either samples or ready - isolated RNA and will decide how many genes will be profiled.
To gain insight into how genes and pathways were perturbed at the molecular level with loss of bsl1 function, we used RNA - seq to profile transcriptional differences in bsl1 - 1 inflorescence primordia compared with wild - type controls.
Chinnaiyan's lab, which has extensively analyzed how genes and proteins in prostate cancer cells reflect these changes, thought that profiling cells» metabolites would offer an even more «holistic picture of the molecular alterations that occur,» he said.
Dr. Loftus's research has gone on to detail how SOX10 and its downstream target gene MITF coordinately regulate gene expression profiles associated with melanocyte differentiation.
Concurrently, the research group is examining how the epigenetic profile of different candidate genes predicts, and perhaps changes, in response to recovery from PTSD (and negative self - cognitions) along with its neural correlates.
High - throughput ChIP - Seq: One of the major questions for researchers interested in understanding chromatin dynamics is to investigate how protein - DNA interactions alter Epigenetic profiles and subsequent gene expression.
Many online dating sites have personality profiling, there is gene testing, and yet we are still so confused about how to mate successfully.?
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