Sentences with phrase «how genes control»

Then, I joined Benoit Bruneau's lab at Gladstone to study how genes control the process of heart development and how abnormalities in these genes cause congenital heart diseases.

Now that scientists understand how these genes control the heart, they can begin to piece together how heart disease disrupts this regulation.

This study will help us to understand how genes control biological processes like cell division and behaviour.

«If we know how genes control drug response, we can create a statistical model that shows us what will happen before using the drug,» said Wu, who is also a member of Penn State's Huck Institutes of the Life Sciences.

Dr. Saptarsi Haldar's research focuses on how cells in the cardiovascular system control gene expression and how these gene control mechanisms go awry during disease.

Not exact matches

How can evolution be reasonable when genes lose information when it mutates, even when they are deliberately manipulated in labs, under controlled environments?

There is also the possibility that dairy fat controls genes that influence how your body uses the fat that's already in your system.

RNA molecules can attach to particular DNA sequences to help control how much protein these particular genes produce within a given time, and within a given cell.

The scientists also discovered that the stem cells released tiny packets of microRNA, bits of genetic material that control how genes function.

«The key point here is that we can say something about how the gene acts to influence this behavior — that is, is by functioning as a chemical messenger in cells that control this behavior in the brain.

Now a gene that causes such disorders has been found, and it may help unravel a deeper mystery: how it is that the left side of our brain controls the right side of the body, and vice versa.

In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNA.

«We now need to identify how this effect is pass through multiple generations by investigating the effects alcohol has on the genome and epigenome (molecules that control gene translation),» said Cameron.

Biologists now know that the genome sequence holds only a small part of the answer, and that key elements of development and disease are controlled by the epigenome — a set of chemical modifications, not encoded in DNA, that orchestrate how and when genes are expressed.

This study took a different approach — targeting a drug to a protein that controls how genes are turned on and off, early in the viral replication process.

By tracking activity in almost all the genes of a free - living archaeon — which, like a bacterium, is a prokaryote — Bonneau was recently able to piece together how the genes affected one another's expression, enabling him to map the organism's «control circuit» as if it were a machine.

In a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expression.

According to Joanne: How does a mouse build a burrow, and do genes help control this behavior?

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

By tweaking different fly genes and counting how many neuron types were produced as the flies matured, the team identified a network of five genes that work together like coordinated control switches to guide the precursor cells» transformation to mature neurons.

This «shape - shifting» or «transformer» behavior explains how the Ebola virus can control a multi-step viral lifecycle using only a very limited number of genes.

Although the researchers don't know precisely how the chaperone molecule works, the difference was unmistakable: Less than 40 % of cells treated with gene therapy had clumps, compared to 70 % of controls.

The team's next goal is to identify genes that interact with GmHs1 - 1 and understand how they work together to control calcium and possibly other mineral content.

The genes that interest Patel determine body plans, controlling how and when a nascent organism forms its limbs, mouth parts, antennae, etc..

The newly unmasked genes play a role in three distinctively different bodily functions, including systems that control inflammation and cholesterol and the regulation of how brain cells clean up toxic proteins.

Instead, the changes happen to certain chemical markers on the DNA that control how much any particular gene is expressed.

One describes how proteins are made, and the other instructs the cell on how genes are controlled.

«Although we know that ZMYND11 controls RNA polymerase II travel ratio in the gene body, we still don't know how this protein, which does not physically interact with polymerase II, actually achieves this regulation,» Shi said.

Research into the drivers of genetic diversity has largely focused on gene expression, which controls how much of a given protein will be made, when, and in what tissue.

Molecular geneticists dream of having a similarly comprehensive view of networks that control genes: For example, they would like to identify rules explaining how a single DNA sequence can express different proteins, or varying amounts of protein, in different circumstances (see p. 80).

The gene in question seems to work by controlling how ants perceive pheromones that tell them who's a queen and who isn't.

These chemical modifications of DNA play an important part in controlling how genes are expressed.

This describes naturally - occurring modifications to genes that control how they are expressed.

But while this study has proved that the technique works in a simple organism, it could also be applied to other bacterial species, yeast or even human cells to find useful information about how genes are controlled and how they can be manipulated.

In a study described in the January 28 issue of Nature Neuroscience, the Hopkins team describes this new gene control mechanism and how it may contribute to Rett Syndrome, a nervous system disorder affecting mostly girls that causes problems with movement and communication.

Still unclear is how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that controls how well cells resist or repair these stresses.

The finding could reveal much about how cells control gene activity, and also illuminate cancer, multiple sclerosis, and other diseases spurred by faulty gene expression.

Over the past decade Hariri has looked for evidence of how other genes affect other aspects of our minds, including self - control and memory.

They also demonstrated significant advantages of editing gene regulatory sequences in their native location to uncover new functionalities that could lead to a better understanding of how control switches work to turn genes on and off in the body.

It plays an important role in how cells sense their neighbors and, by controlling gene expression, determines which cells should develop into different types and how much they should grow - like a master controller.»

So what makes humans different from our nearest relatives is that we have lost some regulatory DNA (12 March, p 3 and p 6) which controls how genes are expressed.

Further studies showed that very similar genes controlled the process in animal and human cells, and also helped piece together how the genes work together to keep the cell's recycling centers running.

«How parasites hack victims to seize control of genes in plant - to - plant warfare.»

«At the LMB, you can approach big questions, like how is gene expression controlled?»

This result reflected earlier findings that ILC and T cell subclasses produce similar sets of cytokines, but also revealed differences in how the two cell types control the activities of these key immune response genes.

While the «genome» of thousands of individual genes is like data stored on a computer disk, the «epigenome» is like a computer program that controls how stored data are read.

«How a developmental gene controls feeding behavior.»

Genes control to a great extent how long an organism can live.

In humans and all multicellular organisms, three different types of RNA producing enzymes control how genes are transcribed.

Dr Kat Arney, science communication manager at Cancer Research UK, said: «Only a tiny fraction of our DNA contains actual genes, and we know that at least some of the bits in between — often dismissed as «junk» — play important roles in controlling how genes get switched on and off at the right time and in the right place.