Speakers include Penn State's Peter Hudson, who talks about disease transmission; Oxford's Oliver Pybus, on
how genome analysis exonerated health care workers accused of infecting children with HIV; and N.Y.U.'s Martin Blaser on our disappearing stomach flora.
Not exact matches
First Farmers (Middle East and Europe 3,000 - 14,000 years ago)
Analyses of hundreds of
genomes show
how early Middle Eastern farmers spread to Europe, mixed with hunter - gatherers and adapted to agricultural diets, including through a lactase gene mutation that allowed people to drink milk after childhood.
Professor Ed Feil, joint lead author from the Milner Centre for Evolution, at the University of Bath, said: «We've developed user - friendly
analysis software that demonstrates
how whole
genome sequence data can be a powerful tool for pan-European surveillance of MRSA and other important pathogens.
In the February 23, 2015 online edition of Nature Genetics, these researchers describe
how the comparative
analyses of these
genomes allowed them to track the evolution of mycorrhizal fungi.
To shed light on
how co-infection may affect evolution, Sentandreu sequences parts of the
genome of both viruses and
analyses genetic variability and adaptive evolution in co-infected patients.
A new
analysis of the crustacean's
genome supports this unlikely origin and may help explain
how the animal has subsequently spread and adapted to so many new environments.
This represents a particular challenge to disease gene
analysis:
How do we analyze genes and establish genotype - phenotype relationships against a background of high natural
genome sequence variability?
The commission took a stab at these complicated questions, issuing new
analysis and recommendations for
how to manage these increasingly complex issues in medicine, research and with direct - to - consumer tests that allow a patient to send in a cheek swab and get health information (like the personalized
genome services kit offered by 23andMe, that was recently blocked by the U.S. Food and Drug Administration).
Together, all five RMs serve as a collection of well - characterized, whole
genome standards that can tell a laboratory
how well its DNA sequencing processes are working by measuring the performance of the equipment, chemistry and data
analysis involved.
Another way to glean information from the
genome is to check
how it is folded — a perfect job for 3D
analysis by a computer.
Because Kosik's team had information on the
genome sequence around the mutation, they could use something called identity - by - descent
analysis to determine
how the people in the study were related.
«Without computer
analysis of sequencing results, we would not have been able to determine relationships between DNA methylation,
how accessible regions of the
genome were, global gene expression, or the emergence of cancer cells,» says González - Avalos, a graduate student in UCSD's Bioinformatics Graduate Program.
Associate Professor D'Amato said: «Primarily a proof - of - concept investigation, our pilot study reinforces the idea that large - scale
analyses should be undertaken to unravel
how variation in the entire human
genome relates to variation in the human microbiota.»
WABI has state - of the art competence and technical know -
how in large - scale sequence data
analysis, including transcriptomics, variant detection and de novo
genome assembly.
Their
analysis of the passenger pigeon's
genome is the first study to reveal
how natural selection and genetic recombination shape a
genome in an abundant population, as was the passenger pigeon's before the arrival of European settlers to North America.
At the same time, we will integrate today's discovery into the prostate cancer module in our personal
genome analysis service deCODEme ™, enabling our subscribers to stay abreast of
how the latest discoveries in human genetics may relate to their
genome,» said Kari Stefansson, CEO of deCODE.
Genome analysis revealed
how whales have evolved and mated across neighboring species.
I am using computational
analysis and modeling to visualize
how plant
genomes have evolved over time, particularly those of staple crops.