Collective unconscious:
How gut microbes shape human behavior.
By comparing
how gut microbes from human vegetarians and grass - grazing baboons digest different diets, researchers have shown that ancestral human diets, so called «paleo» diets, did not necessarily result in better appetite suppression.
What's more, the studies suggest
how our gut microbes make the immune system turn against nerve cells — a finding that could lead to treatments, like drugs based on microbial byproducts, that might improve the course of the disease.
Not exact matches
How do the
microbes within cheese interact with the natural microbiota of the human
gut and can cheese be used to assist in maintaining a healthy
gut microbiota?
Although the vast majority of research on the
gut microbiome has focused on bacteria in the large intestine, a new study — one of a few to concentrate on
microbes in the upper gastrointestinal tract — shows
how the typical calorie - dense western diet can induce expansion of
microbes that promote the digestion and absorption of high - fat foods.
It didn't take her long to decide that she missed lab work; in 1985 she joined IFR with an in - house fellowship, investigating
how gut epithelial cells interact with
microbes.
«
How altered
gut microbes cause obesity.»
«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between
gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine
how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.
The advance, reported in Proceedings of the National Academy of Sciences (PNAS) journal, for the first time allows scientists to analyze
how normal
gut microbes and pathogenic bacteria contribute to immune responses, and to investigate IBD mechanisms in a controlled model that recapitulates human intestinal physiology.
«Rather than soil
microbes and plants, I studied the bugs in your
gut and
how they influence it,» Bry says.
In this latest advance reported in PNAS, the Wyss team showed that the human
gut - on - a-chip's unique ability to co-culture intestinal cells with living
microbes from the normal
gut microbiome for an extended period of time, up to two weeks, could allow breakthrough insights into
how the microbial communities that flourish inside our GI tracts contribute to human health and disease.
«Like zebrafish, we have this rich source of
gut microbes that have figured out
how to coexist with us and soothe the immune system,» she says, adding that «there is enormous potential to harness those mechanisms» to address ailments such as inflammatory bowel disease and other chronic inflammation.
Westerners have a less - diverse
gut microbiome compared to hunter - gatherers, but
how and why these
microbe collections diverged has largely remained a mystery.
To better understand
how changes in diet, lifestyle, and exposure to modern medicine affect primates»
guts, a team of researchers used DNA sequencing to study the
gut microbes of multiple non-human primates species.
To better understand
how changes in diet, lifestyle, and exposure to modern medicine affect primates»
guts, a team of researchers led by University of Minnesota computer science and engineering professor Dan Knights, veterinary medicine professor Tim Johnson, and veterinary medicine Ph.D. student Jonathan Clayton, used DNA sequencing to study the
gut microbes of multiple non-human primates species in the wild and in captivity as a model for studying the effects of emigration and lifestyle changes.
Warinner and colleague, Cecil M. Lewis, Jr., co-direct OU's Laboratories of Molecular Anthropology and Microbiome Research and the research focused on reconstructing the ancestral human oral and
gut microbiome, addressing questions concerning
how the relationship between humans and
microbes has changed through time and
how our microbiomes influence health and disease in diverse populations, both today and in the past.
In a recent paper in the journal Trends in Ecology and Evolution, Shapira, who studies the
gut microbes of the nematode C. elegans, reviews evidence that demonstrates
how microbiotas affect and contribute to host evolution, either by evolving along with the host, or by stepping in at critical moments to help the host adapt to a new environmental challenge.
A new study on the crosstalk between
microbes and cells lining the
gut of mice shows just
how cooperative this environment can be.
«Understanding
how pain is bugging you: Scientists uncover critical role for
microbes in mediating
gut pain.»
A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of
gut microbes, which in turn shaped
how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.
She knew that signals from the
gut can affect
how bone forms and gets reabsorbed, so her team took fecal samples from control mice in each of the three experiments and analyzed their
gut microbes.
The story they put together shows
how Salmonella usurps
microbes that normally populate the
gut.
Meanwhile, the latest book by U.S. neurologist and author David Perlmutter, Brain Maker: The Power of
Gut Microbes to Heal and Protect Your Brain — for Life, has quickly found its way onto The New York Times bestseller list, with alluring tips on
how to achieve neurological wellness through dietary changes and probiotic enemas.
In the second study, Thomas Gajewski at the University of Chicago and colleagues noticed differences in
how quickly tumours grew in two groups of mice with different sets of
gut microbes.
And while scientists have made strides in recognizing various strains of
gut microbes by identifying their molecular DNA signature, they still have a long way to go to determine what each does and
how each functions, Bienenstock says.
Terry Hwa's lab has been working on quantitative descriptions of
how genes, proteins and chemicals work together to coordinate the physiological responses of the
gut bacterium E. coli, and is more recently studying the interaction of
gut microbes with each other and with the host environments.
This suggests that some
microbes in a hamster's
gut might influence
how it behaves and interacts with others.
If Hadany and Lewin - Epstein's theory holds up, it could have a profound impact on
how we approach medical interventions that affect
gut microbes.
Three researchers at the forefront of research on the microbiome - brain connection recently spoke with The Kavli Foundation about
how microbes communicate with the brain and whether we can modify the
gut microbiome to treat disorders of the brain and mind.
However, a long, hard look at the methods through which animals are intensively reared for food production has led Dr. A-V to start to consider
how modern interventions in animal husbandry might damage the
gut microbes, and hence the health, of farm animals.
The problem is that being regularly stressed depletes your entire system (including your
gut microbes) and directly affects your digestion and
how well you can absorb nutrients.
How do the
microbes within cheese interact with the natural microbiota of the human
gut and can cheese be used to assist in maintaining a healthy
gut microbiota?
But
how exactly does making and eating fermented food change a person's
gut microbes?
Your social contact defines
how much stress you interact with, and both can influence the cocktail of
microbes in your
gut.
Read on to learn
how the
gut influences kidney function, its role in chronic kidney disease, and
how we can manipulate our
gut microbes to promote healthy renal function.
In fact, exactly
how the
gut microbiome «interacts with foods to produce health conditions» is considered a new and dynamic area for further research by individuals on all sides of the red meat - colon cancer debate.10 For example, researchers at Harvard Medical School are studying fecal samples to assess the impact of red meat intake on
gut microbes and their byproducts, which the researchers speculate may influence «biological pathways associated with colorectal cancer and other digestive diseases.»
(Excerpt from
How to Boost Your Child's Immune System: What you need to know to strengthen your child's health and prevent illness) Optimizing your children's gut flora is not that difficult, once you know what to avoid and how to replenish and maintain beneficial microb
How to Boost Your Child's Immune System: What you need to know to strengthen your child's health and prevent illness) Optimizing your children's
gut flora is not that difficult, once you know what to avoid and
how to replenish and maintain beneficial microb
how to replenish and maintain beneficial
microbes.
And while we're still learning more each day — mapping what's going on with those
microbes and
how they influence our states of health and illness, from
gut to brain and immunity to pain — it's time for each one of us to take the tiger by the tail.
So red meat affects both your
gut microbiota and your health, and
gut microbes appear to be playing a role in determining
HOW red meat affects your health.
In my previous article, I described
how each of us possesses a
gut microbiota with a unique population of
microbes and that our uniqueness may influence the efficacy of the probiotic supplements that we use.
In Brain Maker, Dr. Perlmutter explains the potent interplay between intestinal
microbes and the brain, describing
how the microbiome develops from birth and evolves based on lifestyle choices,
how it can become «sick,» and
how nurturing
gut health through a few easy strategies can alter your brain's destiny for the better.
Here's an update post, April, 2015:
Gut Bugs, Probiotics, Prebiotics... And
how our
microbes make us who we are.