Sentences with phrase «how human stem»

«The region selective - state of these stem cells is entirely novel for laboratory - cultured stem cells and offers important insight into how human stem cells might be differentiated into derivatives that give rise to a wide range of tissues and organs,» says Jun Wu, a postdoctoral researcher in Izpisua Belmonte's lab and first author of the new paper.

McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or chimeric animals to see how human stem cells behave during development.

Not exact matches

Indeed, I see a lot of the contempt for animals I see in this world stemming from the human hubris of assuming that we are fundamentally separate from the animal world, which we clearly aren't and evolutionary theory explains a lot about how deeply rooted in the rest of the animate world we are.

Famous for: Uses stem cells to grow human bone - potentially changing how surgeries are performed.

Two expert panels and breakout training sessions demonstrated how STEM education taught through the prism of human rights helps inspire students, puts the scientific method to work in the collection and eventual application of evidence and allows students to design and build projects that address civic issues.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

«We've figured out for the first time how to produce these cells from human embryonic stem cells literally by the billions and billions,» Lanza says.

Published in Molecular Neurobiology, the study led by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in Stem Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cells.

Minuscule blobs of human brain tissue have come a long way in the four years since scientists in Vienna discovered how to create them from stem cells.

Now, many research advocates are wondering how Price's mix of views might play out in the new administration's approach to a wide range of issues, including funding, research involving human embryonic stem cells and fetal tissue, and the appointment of a new NIH director.

There were also slight variations between how Zika establishes itself in human liver cells versus neural stem cells, where it is more physiologically relevant.

«It's an exciting development, and we await the outcome over the next year to see how well these cells integrate, and if there are any potential adverse reactions,» says Mike Cheetham of the Institute of Ophthalmology at University College London, one site where research is under way into a human embryonic stem - cell treatment for AMD.

They've figured out how to turn human stem cells into functional pancreatic β cells — the same cells that are destroyed by the body's own immune system in type 1 diabetes patients.

Now comes a first rate example of how CRISPR is changing the pace of biomedical research by linking up with another cutting edge technology — human pluripotent stem cells (hPSCs).

Working with human breast cancer cells and mice, scientists at The Johns Hopkins University say new experiments explain how certain cancer stem cells thrive in low oxygen conditions.

Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to grow brainlike structures using embryonic stem cells, first from mice and then humans.

In 1998, scientists figured out how to derive human embryonic stem cells (ESCs) for medical research, and the method kicked off an intense debate.

Researchers working to understand how to manipulate this powerful tool get their supply from stem cell lines, groups of stem cells derived from animal or human tissue that can reproduce themselves indefinitely.

Studies in diabetic rodents suggest that diabetes may alter the intestine's mucosal lining, which is maintained and regenerated by intestinal stem cells; however, little is known about how this occurs and whether it is relevant to humans.

In the new study, Lipton and his colleagues used human stem cell and mouse models to show exactly how SNO can trigger cell death in Parkinson's disease.

Previous attempts to do the same in monkeys, however, have failed — a disappointment because monkeys are more similar than mice to humans, and thus likely a better harbinger of how stem cell treatments will fare in people.

«If we're going to bring stem cells to the human clinic, we need to know exactly how those stem cells will work.

But Hochedlinger, whose group's paper appears in a new journal called Cell Stem Cell, stresses that researchers still need to study human cells to learn how to reprogram them and have no idea yet which approach would work better in the long run.

The finding could fundamentally change how we look at human stem cell tech: If chimeric monkeys require totipotent cells before they can come into being, it stands to reason that human embryonic stem cell therapy might also require totipotent stem cells to render cures.

- Our results provide new insights into the mechanisms of how POLR3G gene regulates stem cell state, which in turn sheds light on the complex mechanisms with which human embryonic stem cells both self - renew and maintain the ability to differentiate.

«Though the degree to which human embryonic stem cells possess this feature is not entirely clear, by understanding how another complex organism's genome works we ultimately learn more about how our own genome works,» said Zhou.

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

«We hope to determine how this pathway might translate into better stem cell therapies for human disease,» added Agrawal.

The approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem cell recently discovered by the lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.

Upton lamented «a major gap between the science of cures and the way we regulate these therapies,» and DeGette, an outspoken supporter of human embryonic stem cell research, vowed to «take a comprehensive look» at how Congress might intervene.

The new Mount Sinai study reveals how loss of a protein called Sirtuin1 (SIRT1) affects the ability of blood stem cells to regenerate normally, at least in mouse models of human disease.

The two researchers analyzed nationally representative surveys collected between 2002 and 2010 with the goal of better understanding how the U.S. public came to form opinions in the debate over human embryonic stem cell research.

He added: «The fact that all vertebrates regenerate their teeth in the same way with a set of conserved stem cells means that we can use these studies in more obscure fishes to provide clues to how we can address questions of tooth loss in humans.»

«This is essentially a recipe for how to make human inner ears from stem cells,» said Dr. Koehler, lead author of the study and whose research lab works on modeling human development.

Researchers from the University of Cambridge studied a variety of cell lines, including human neural stem cells, to investigate how Zika virus infection can lead to microcephaly.

RIKEN researchers have taken up this challenge, and the work published in Cell Reports details how sequentially applying several signaling molecules to three - dimensional cultures of human embryotic stem cells prompts the cells to differentiate into functioning cerebellar neurons that self - organize to form the proper dorsal / ventral patterning and multi-layer structure found in the natural developing cerebellum.

Working with lab - grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses.

«Stem cell biology has become one of the most exciting and promising areas of research, with real impact on how we treat human disease,» said Gladstone President R. Sanders Williams, MD. «With its meetings and journals, ISSCR has developed a significant role in communicating and promoting groundbreaking advances in the field.

Researchers describe how a microRNA can affect both pluripotency and cell cycle progression in human pluripotent stem cells

Dr. Yamanaka's discovery — how to transform ordinary adult skin cells into stem cells that, like embryonic stem cells, can develop into any cell in the human body.

However, until now, we did not know how they interact with human stem cells and if indeed, they could be used in biomedical applications.

He added: «Truly naive human ES cell lines would not only help answer fundamental questions about how we are made, and be useful for drug screening and tissue therapy, but they would also provide a benchmark against which other types of stem cells could be measured in terms of their effectiveness in stem cell therapy and regenerative medicine.»

«We expect to use this approach to help us better understand how the complexity of the human cortex arises from cells that are spun off through cell division from stem cells in the germinal region of the brain.»

In April of last year, the US Food and Drug Administration invited three large biotech companies - Geron, Advanced Cell Technology, and Novocell - to testify about how to safely test human embryonic stem cell (ESC) products in patients.

A decade later, scientists figured out how to generate another type of all - purpose cell from human skin, known as induced pluripotent stem cells, or iPS.

2007 also saw one of the most game - changing developments in the stem cell field; researchers learned how to create cells like embryonic stem cells, but instead of coming from an embryo these cells are created from adult cells, potentially cells from any tissue in the human body.

Michigan State students note how Willie Soon now refutes research indicating adverse impacts from ocean acidification, a global crisis that is married to climate change (both problems stem from humans burning fossil fuels and releasing carbon dioxide into the atmosphere).

In findings appearing online today in Cell Stem Cell, researchers in the laboratory of Gladstone Investigator Yadong Huang, MD, PhD, describe how they transferred a single gene called Sox2 into both mouse and human skin cells.

Mesenchymal Stem Cells: Around the same time that researchers were figuring out how to isolate embryonic stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell famStem Cells: Around the same time that researchers were figuring out how to isolate embryonic stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell famstem cells from humans, yet another large group of stem cells was finally admitted into the stem cell famstem cells was finally admitted into the stem cell famstem cell family.

By figuring out how frogs regenerate tissue, Tseng hopes she and other scientists can learn how to get stem cells to better repair or regrow tissue in humans.