Sentences with phrase «how immature cells»

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To understand how the bacteria affected the immune system, the researchers grew L. reuteri in liquid and then transferred small amounts of the liquid — without bacteria — to immature immune cells isolated from mice.

Now, researchers at The Wistar Institute have discovered how STAT3 behaves in immature myeloid cells known as myeloid - derived suppressor cells (MDSCs), and they believe they have found the basis for a much more effective method of using STAT3 inhibitors to stop cancer progression in its tracks.

In a flurry of papers published early this spring, they provided the first experimental evidence of how Zika attacks immature brain cells and how it disrupts the carefully orchestrated events that ultimately build a healthy brain.

A critical test reported in the paper demonstrates how insidious even a few perpetually immature iNKT cells can be.

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

A major scientific puzzle, said Singh, has been how and why immature hematopoietic stem cells initially express genes that are characteristic of more than one cell lineage.

The team, headed by professor Juan Carlos Ispizúa Belmonte, Ph.D., of the Gene Expression Laboratory and including professor Fred Gage, Ph.D., of the Laboratory of Genetics, demonstrates how a DNA - binding protein called Nanog coaxes mouse ES cells trying to differentiate into muscle cells back into an immature state.

Gage and Ghosh discuss how human skin cells induced to return to an immature state («induced pluripotent stem cells» or IPS cells) are revolutionizing our understanding and treatment of mental and neurodegenerative disorders, such as Parkinson's disease, as well as leading to new models of drug development for all diseases.