Sentences with phrase «how immune cell function»
An extensive database identifying immune traits, such as how immune cell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal Cell.
https://www.sciencedaily.com/
«This finding is very new and very important, because it shows us the role of cellular metabolism in how these immune cells function.»
Not exact matches
How microRNAs might intercept immune cells in cancer is unknown and we were able to provide insight into a critical means by which cancer cells exploit miR - 183 to dampen immune cell function.»
But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood.
Researchers from Brigham and Women's Hospital (BWH), Harvard Medical School (HMS), the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and University of Chicago report findings demonstrating how genetic variations among healthy, young individuals can influence immune cell function.
«These results represent a significant advance in our understanding of how commensal microbes can regulate host intestinal immune responses and suggest that the identification of downstream targets in macrophages and dendritic cells along the GM - CSF axis can help the rationale design of novel strategies for the treatment of IBD patients with defective GM - CSF function,» explained Dr. Merad.
«ILCs were discovered less than a decade ago, but the parallels between them and T cells will enable us to more quickly understand how they work and to develop ways to enhance or inhibit their function in treating a variety of immune and inflammatory diseases.»
In an effort to further define the importance of GATA - 3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8 + T - cell type of the immune system.
However, researchers are still learning how best to implement immunotherapy regimens, making monitoring of the immune response during treatment development and implementation critical to predicting how the modified cells will function, and how the immune system as a whole will react.
«Over the past ten years, several research groups, including our own, have shown the importance of certain immune cell subsets in preventing or exacerbating heart disease in mice, but we are just beginning to understand how the metabolism and function of these immune cells change during cardiovascular disease progression in humans,» says Hedrick.
The company showed how they first defined A2A as the receptor required for mediating the effect of adenosine on immune cells within the tumor microenvironment and reported the characterization of a novel immuno - oncology - dedicated adenosine receptor 2A antagonist that functions in the high adenosine concentration found in tumors.
Our research is focused on understanding how the functions of immune cells, such as monocytes and T lymphocytes, change during the progression of cardiovascular disease and cancer.
A fact sheet that provides an overview of how the immune system functions and describes the actions of biological therapies, such as monoclonal antibodies, cytokines, therapeutic vaccines, the bacterium bacillus Calmet - Guérin, cancer - killing viruses, gene therapy, and adoptive T - cell transfer.
His discoveries include insights into how changes in gene expression affect T cell exhaustion, a waning of immune function that occurs in response to chronic viral infection and cancer.
Researchers also provided new details of how the Nrp1 pathway functions, including evidence that along with bolstering the ability of regulatory T cells to suppress the immune response, the pathway also helps maintain a stable population of regulatory T cells.
Join us for this informative session to get practical advice on designing and performing T cell activation assays on Seahorse XF Analyzers; how to interrogate and quantify glycolytic and mitochondrial function; and generating and interpreting metabolic phenotypes of primary immune cells.
· Immune Function — key immune cell constituents of and how the immune system works and cancer and the immune system, causes of immune system impairment including food allergens, leaky gut, nutrient deficiencies nutrient - depleting medications and immunomodulation therapies including mistletoe, and immune system reboot;
Through specialized blood testing we can take a look inside the body to measure vitamin levels, minerals, antioxidants, amino acids, and view overall immune system functioning; We can also get a detailed look at carbohydrate metabolism, genetic code, and even see how quickly your cells are aging.