The model will be a valuable tool for studying how stem cells give rise to the various cells of the immune system,
how immune cells kill cancer cells and fight infections, and
how immune cells respond to radiation and chemotherapy, two major treatments for many cancers.
«This finding is very new and very important, because it shows us the role of cellular metabolism in
how these immune cells function.»
He also conducts research that focuses on the GITR and OX40 pathways, as well as
how some immune cells, known as myeloid - derived suppressor cells, influence anti-tumor immune responses.
An international team of researchers reveals
how immune cells called macrophages activate to kill parasitic worms.
CRI will present the 2016 William B. Coley Award for Distinguished Research in Tumor Immunology to Ton N. Schumacher, Ph.D., for his contributions to our understanding of
how immune cells identify and target tumor - specific neoantigens, and how this capability can provide anti-tumor immunity.
We are also working to show how changes in the structure of chromosomes affect heart development, and to determine
how immune cells contribute to the build - up of plaque in arteries.
She wants to expose
how immune cells sense pathogen - triggered changes in fatty acid synthesis and then relay the message to limit inflammation.
«Our study shows for the first time exactly
how immune cells sense the virus and how the virus uses one of its proteins to tune its stealthiness and infectivity,» says senior study author Nicolas Manel of the Institut Curie.
Beth Stevens and her network of collaborators are showing
how immune cells sculpt connections in the brain
In a study published in the Journal of Clinical Investigation, researchers looked at
how immune cells reached the myelin, focusing on the barrier between brain tissue and the rest of the body.
«Scientists discover
how immune cells die during HIV infection; Identify potential drug to block AIDS.»
This allows the researchers to observe how cells work within these environments and potentially enables them to study biological scenarios such as where cancer grows or
how immune cells interact with other cells, which could lead to the development of new drugs.
The findings reveal
how immune cells specialize to protect the skin and suggest that staying out of the sun could cause harm if carried too far.
The scientists hope understanding
how immune cells adapt as they enter different tissues will spur the design of better, more specific, medicines.
The study could provide useful information on
how immune cells could respond to allergens to prevent allergic symptoms in humans.
New research from Australian and Singaporean scientists has revealed
how immune cell «spies» are created, providing clues on how the immune system could be manipulated to better fight disease.
Their paper, which appears in Nature Communications, describes
how an immune cell recruited to the tumor induces the programmed suicide, or apoptosis, of the killer T cells harnessed by many immunotherapies.
An extensive database identifying immune traits, such as
how immune cell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal Cell.
Of note, the current study is part of a recent surge in NYU Langone findings on pancreatic cancer, including studies on how first - responder cells turn off the immune response, the role of the drug nab - paclitaxel in tumor biology, cancer cells» unique fuel sources, and
how immune cell infighting drives the disease.
We identify and characterize every cell and see
how each immune cell works as part of a system to prevent or exacerbate disease.
Not exact matches
Today his company is developing a new cancer vaccine technology that teaches
immune cells how to recognize and remove tumor
cells.
Hoping to learn something about
how the human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes called T
cells, common to the
immune systems in both mouse and man.
And yet the intricacies of that science — the precise mechanisms through which adrenal glands release glucocorticoids and
immune cells send out cytokines — don't tell us much about
how best to help children in trouble.
This article is questionable as it has no links or actual references to the studies it talks about, like someone above has mentioned also there is no information on
how the diagnosis were made, and lastly it does not take into account that celiac disease is NOT an allergy, it is an auto
immune disease where the body attacks its own
cells confusing them with gluten proteins, it is not about tolerance, I would not be trusting this information, do lots of research on your own from legitimate scientific sources before making a decision.
The 2016 People's Choice Award went to Emmanuelle Alaluf of the Free University of Brussels, for her video using ballet and other dance styles to show
how tumor
cells evade the
immune system.
During the sessions, U.S. and Cuban scientists explored such topics as the molecular mechanisms cancer
cells employ to evade the body's
immune system, new tools to image and manipulate that system, and ways to rethink
how such therapies can best be deployed to reach patients where they receive health services.
A group of the nation's leading cancer research scientists and their Cuban counterparts are exploring
how to advance cancer therapy, diagnosis, and prevention, including the use of immunotherapy to harness the body's
immune systems to attack and eliminate cancer
cells.
«Our lab specializes in developing novel genetic methodologies to study T
cell repertoires, but we had never applied this technology to study
how the
immune system responds to an infection,» says Emanual Maverakis, M.D., associate professor of dermatology at the University of California, Davis School of Medicine.
«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial
cells and the
immune system, but so far it has been impossible to determine
how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.
Understanding
how dendritic
cells are created will aid scientists in finding ways to boost the
immune response to infections or dampen it in autoimmune diseases such as lupus and rheumatoid arthritis.
To understand the mechanism of
how Neu5Gc affects the human
immune system, researchers analyzed various
cells of the
immune system that play a role during an inflammatory reaction.
In the eight years since then, Markovic and other researchers have discovered some remarkable similarities in
how cancer
cells and placental
cells regulate the
immune system.
«If we learn
how to control dendritic
cells, we could strengthen our
immune response to infection when needed, or weaken the action of certain
immune cells that attack the body's own tissues in autoimmune disease.»
«The pathway mainly involves signalling via the brains»
immune cells, and thus differs from
how today's drugs operate.
Lagasse, based at Pitt's McGowan Institute for Regenerative Medicine, has discovered
how to turn any one of the body's 500 lymph nodes — the small, oval - shaped organs where
immune cells gather to fight invading pathogens — into an incubator that can grow an entirely new liver.
It is similar to
how radiation and chemotherapy are used to «condition» patients for a bone marrow transplant, to improve engraftment of transplanted
immune cells.
Now cancer researchers and immunologists at Sweden's Karolinska Institutet have discovered
how cancer
cells can infiltrate the lymphatic system by «disguising» themselves as
immune cells (white blood
cells).
The Australian team is now attempting to identify the strain of the man's virus to see
how it compares to other HIV strains that require CCR5 to slip into
immune cells.
Publishing online this week in
Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying
immune mechanism that explains why to
how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema.
This may explain
how cancer
cells escape detection by our body's
immune system.
Dendritic
cells catch invaders and tell the
immune system when and
how to respond.
Cancer
cells are smart; they know
how to hide from the body's own
immune system.
More importantly, it opens up exciting avenues of research to explore
how restoration of p53 with drugs such as those that target ERAP1 can help to harness the
immune system to recognise and destroy cancer
cells.»
«With this discovery in our hands, we'd now like to try to find out which additional
immune -
cell properties cancer
cells have and study
how they affect the metastatic process,» says Dr Fuxe.
«Now that we know Myb has a defining role in the
immune system, we are seeking to understand exactly
how Myb gives Treg
cells the authority to carry out their duty,» Professor Nutt said.
Now we know
how it does this: its active ingredient targets a newly discovered type of
cell that lowers the
immune response.
Although Coley couldn't explain precisely why or
how his toxins worked, modern immunotherapy treatments help T -
cells in the
immune system to recognize specific cancer
cells and attack them.
What's more, the studies suggest
how our gut microbes make the
immune system turn against nerve
cells — a finding that could lead to treatments, like drugs based on microbial byproducts, that might improve the course of the disease.
The team also compared the animals» responses to the therapy's effects in laboratory
cell samples and found that in vitro studies did not predict
how well the viral therapy and
immune response would fight tumor
cells in vivo.
To better understand
how this abnormal distribution of B
cell types in people with uncontrolled HIV affected their
immune response to the virus, researchers compared HIV - specific antibodies derived from both TLM and RM B
cells.