Sentences with phrase «how immune system cells»

«The retraction states that Mignot and his colleagues were unable to replicate the results of the ELISpot assay, a widely used method for measuring how immune system cells such as T cells respond to fragments of foreign proteins, called antigens,» Underwood writes.

Not exact matches

Hoping to learn something about how the human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes called T cells, common to the immune systems in both mouse and man.

The 2016 People's Choice Award went to Emmanuelle Alaluf of the Free University of Brussels, for her video using ballet and other dance styles to show how tumor cells evade the immune system.

During the sessions, U.S. and Cuban scientists explored such topics as the molecular mechanisms cancer cells employ to evade the body's immune system, new tools to image and manipulate that system, and ways to rethink how such therapies can best be deployed to reach patients where they receive health services.

A group of the nation's leading cancer research scientists and their Cuban counterparts are exploring how to advance cancer therapy, diagnosis, and prevention, including the use of immunotherapy to harness the body's immune systems to attack and eliminate cancer cells.

«Our lab specializes in developing novel genetic methodologies to study T cell repertoires, but we had never applied this technology to study how the immune system responds to an infection,» says Emanual Maverakis, M.D., associate professor of dermatology at the University of California, Davis School of Medicine.

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

New research from Australian and Singaporean scientists has revealed how immune cell «spies» are created, providing clues on how the immune system could be manipulated to better fight disease.

To understand the mechanism of how Neu5Gc affects the human immune system, researchers analyzed various cells of the immune system that play a role during an inflammatory reaction.

In the eight years since then, Markovic and other researchers have discovered some remarkable similarities in how cancer cells and placental cells regulate the immune system.

Now cancer researchers and immunologists at Sweden's Karolinska Institutet have discovered how cancer cells can infiltrate the lymphatic system by «disguising» themselves as immune cells (white blood cells).

This may explain how cancer cells escape detection by our body's immune system.

Dendritic cells catch invaders and tell the immune system when and how to respond.

Cancer cells are smart; they know how to hide from the body's own immune system.

More importantly, it opens up exciting avenues of research to explore how restoration of p53 with drugs such as those that target ERAP1 can help to harness the immune system to recognise and destroy cancer cells.»

«Now that we know Myb has a defining role in the immune system, we are seeking to understand exactly how Myb gives Treg cells the authority to carry out their duty,» Professor Nutt said.

Although Coley couldn't explain precisely why or how his toxins worked, modern immunotherapy treatments help T - cells in the immune system to recognize specific cancer cells and attack them.

What's more, the studies suggest how our gut microbes make the immune system turn against nerve cells — a finding that could lead to treatments, like drugs based on microbial byproducts, that might improve the course of the disease.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

«We already know how to stimulate the immune system to make CD8 T cells by vaccination.

They've figured out how to turn human stem cells into functional pancreatic β cells — the same cells that are destroyed by the body's own immune system in type 1 diabetes patients.

«How to reprogram cells in our immune system: The discovery could improve treatments for autoimmune diseases and cancer.»

More precisely, they discovered how to turn pro-inflammatory cells that boost the immune system into anti-inflammatory cells that suppress it, and vice versa.

But exactly how the immune system works remains, in many ways, a mystery, as there are numerous cell types whose functions and interactions with our immune systems have not been well understood.

Current laureates in residence include Peter Doherty, who shared the 1996 prize for discovering how the body's immune system recognizes virus - infected cells, and Barry Marshall and Robin Warren, who received the award last year for their discovery that the bacterium Heliobacter pylori causes stomach ulcers and gastritis.

Now, thanks to the new mouse model, it will be possible to study how renal tumors are able to develop in an environment with a normal immune system, and how cancer cells manage to evade the immune system's attacks.

Associate Professor Palmer said that this next - generation test showed that HIV hides in the body's immune memory T - cells, which is how it avoids detection from the immune system.

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain.

And researchers must figure out how to build in some core features: the necessary blood vessels, immune - system cells called microglia and connections from other brain regions, such as the thalamus and cerebellum.

The immune system is loyal to cells in the body, but how this works is not fully understood.

In the new study, published in the Journal of Experimental Medicine, the scientists found that it is also involved in how cells in the immune system develop with age.

When we think of how we fight disease, the image of cells in our immune system fending off microbial invaders often comes to mind.

To understand how the bacteria affected the immune system, the researchers grew L. reuteri in liquid and then transferred small amounts of the liquid — without bacteria — to immature immune cells isolated from mice.

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez - Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection.

«How stem cells can be activated to help immune system respond to infection.»

In an article published in the January issue of Cancer Cell, the researchers describe how a new type of immunotherapy drug targeting the protein TIM - 3 works to stimulate the immune system.

This study showed how HIV attempts, but fails, to productively infect most of the immune system's CD4 T cells.

In an effort to further define the importance of GATA - 3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8 + T - cell type of the immune system.

After all, that would seem to offer a neat explanation for how HIV causes the collapse of the immune system by suppressing T cells.

«One of the least understood aspects of this process is how the excess milk and large numbers of dead cells are removed from the mammary gland without substantial activation of the immune system,» says Matthew Naylor, a cancer biologist at the University of Sydney in Australia.

It is unclear exactly how an image gets translated into a mustering of immune cells, Schaller says, but many neurochemicals connect the brain to the immune system — more studies are needed to tease out the exact chain of events.

The discovery is published in Cell Reports, and has significant implications for our understanding of how the immune system responds to infections.

Rather than the body's immune system destroying its own tissue by mistake, researchers at the University of Bristol have discovered how cells convert from being aggressive to actually protecting against disease.

Researchers at the University of Bonn and the Ludwig - Maximilians - Universität of Munich have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin.

The challenge has been how to remove the molecular badges — A, B, and AB — that lie on the surface of the red blood cells and can trigger rejection by a patient's immune system.

However, researchers are still learning how best to implement immunotherapy regimens, making monitoring of the immune response during treatment development and implementation critical to predicting how the modified cells will function, and how the immune system as a whole will react.

The research team investigated how Escherichia coli (E. coli), one of the first bacteria to colonize the intestine at birth, evolved in healthy mice and in mice that did not have lymphocytes, cells of the immune system.

A study led by researchers at Stanford's School of Medicine reveals how T cells, the immune system's foot soldiers, respond to an enormous number of potential health threats.

Back then, biologists were struggling to learn how the fierce little warriors of the immune system — the white blood cells — know to attack invading pathogens but not the body itself.

«It was known that acute exposure to pyrethroids could lead to immune dysfunction, and that the molecules they act on can be found in immune cells; now we need to know more about how longer - term exposure affects the immune system in a way that increases risk for Parkinson's.»