A better understanding of
how myosin helps cells move and divide could even stop cancer in its tracks, Yengo said.
These insights provide details about
how myosin motor proteins work, and this knowledge could advance the understanding of diseases related to movement on a molecular level.
Not exact matches
«We thought we knew everything about
myosin —
how it works,
how it makes muscles contract,» he says.
How binding of a small molecule can increase the performance of a muscle by promoting an increase in
myosin motor force was unclear.
The work by the Houdusse team and Cytokinetics highlights
how specific modulators of
myosin activity have great potential to provide new treatments against human diseases.
Complementary collaborative work between Cytokinetics and the team headed by Anne Houdusse has also uncovered
how highly specific small molecules can stop smooth muscle
myosin activity.