Sentences with phrase «how nucleosomes»
«It is important to understand how nucleosomes are moved, ejected or restructured, as this will affect the accessibility of promoter DNA, which in turn influences the expression of the corresponding genes,» explains David Shore, professor at the Department of Molecular Biology of the Faculty of Science at UNIGE.
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In January, a team at the University of Washington, Seattle, described in Cell a test that relies on tissue - specific differences in how DNA is packaged in structures called nucleosomes.
«Our cryo - EM images help us understand how the complex can recognize the presence of a histone modification in one nucleosome and place the same tag onto a neighboring nucleosome.»
In the new study, Tulin and his colleagues reevaluated how PARP1 is activated by changes in the nucleosome.
Researchers from the University of Geneva (UNIGE) and the Ecole polytechnique fédérale de Lausanne (EPFL), Switzerland, are studying the mechanisms controlling nucleosome dynamics and how this affects gene expression.
The data illustrates how RSC remodels the nucleosome in vitro and shed light on its in vivo function.