«The diversity comes not so much from controlling where in the embryo the homeotic genes are initially expressed, but
how other genes respond to them.»
Regulator genes help determine
how other genes will express themselves, and the researchers suspected that some of these regulators might be making brain development more active in human embryos than in chimps.
«We need to better understand
how other genes may interact with the original mutation to cause cancer in the child,» Maris said.
Over the past decade Hariri has looked for evidence of
how other genes affect other aspects of our minds, including self - control and memory.
Not exact matches
Essentially the model reproduces the inner workings of all of the proteins within the organism and allows scientists to see everything from
how cells interact with each
other to the functions of
genes in a larger context that had not been previously understood.
At some point, our ancestors»
genes became more successful when the ones who knew
how to reciprocate helping
others had a tendency to survive longer.
If Chad and
others argue that naturalistic evolution must be dismissed because we don't know exactly what happened with
gene mutation and transmission frequencies during particular periods of rapid change, then
how can we accept a replacement argument in which we don't even know what happens at all?
The markers have also been used to produce a detailed map of the sugarcane genome that shows
how the
genes are linked to each
other.
In a Policy Forum in the new issue of Science, Theodore Friedmann, M.D., from the University of California in San Diego and colleagues from Montreal and Washington, D.C., highlight
how gene therapy and
other methods of genetic modification are poised to complicate international sports competitions like the Olympics, and indeed already have.
The
genes in the network are thought to be involved in
how brain cells communicate with each
other.
«In addition, changes in
how the
genes are expressed (turned on or off) could be used in the future to predict
how and when the cancer cells will spread to
other parts of the body and
how fast they will grow.»
Comparison of Cinnamon's DNA with that of
other domestic and wild cats has revealed
how domestication shaped cats»
genes.
The disorder arises when some or all of an extra copy of chromosome 21 is present, but exactly
how this additional set of
genes disrupts development, leading to learning difficulties and
other symptoms of Down's, isn't clear.
My tgf - beta
gene was part of a big family of
genes, and I began making phylogenetic trees in order to better understand
how it was related to the
other family members.
For them, the discovery of
how an individual becomes gay is likely to shed light on
how sexuality - related
genes build brains,
how people of any persuasion are attracted to each
other, and perhaps even
how homosexuality evolved.
How can we be so different from
other primates if our
genes are so much the same?
The scientists are tinkering with some simpler genomes as they make them to gain a better understanding of
how genes and
other DNA elements work in the first place.
Other directions for future research, Liu said, include looking at the role of CLOCK in more forms of the disease, learning more about exactly
how CLOCK affects neural circuits to disrupt adequate inhibition of excitatory neurons, and examining whether any of the
genes that CLOCK regulates are especially important in the disorder.
The Duke researchers who made this discovery say it may help explain
how a relatively small number of
genes can create the dazzling array of different cell types found in human brains and the nervous systems in
other animals.
Toshihiro Sassa and Takashi Murayama, the first and second authors of the paper, respectively, say, «we would like to identify the
other genes involved in downstream signaling from this calcium channel to understand
how the signal leads to aversion to high pH.» Sensing alkaline environments is only the first step; the worm must then quickly react to the stimulus by moving away.
Biological kin selection means that organisms may be more willing to help
others in relation to
how many
genes they share.
They lie in a region of chromosome 5 that sits squarely between two
genes that produce cell - adhesion molecules, which govern
how neurons connect to each
other.
This information may help to predict which
other bacterial species might participate in this form of
gene transfer, and to identify just
how widespread the phenomenon is.
Scientists may have discovered the first
gene responsible for
how young — or old — we look to
others.
In
other words, the key is not in individuals» genetic make - up but rather, in
how their bodies employ
genes.
At first, it was difficult to imagine
how pathogens can acquire
genes from Actinobacteria, because they are so different and not at all related with each
other.
The team's next goal is to identify
genes that interact with GmHs1 - 1 and understand
how they work together to control calcium and possibly
other mineral content.
This analysis produced networks that mapped out
how alpha - synuclein is related to
other Parkinson's
genes through well - defined molecular pathways.
Here's a
gene that's central to
how nerve cells communicate with each
other, so it's curious to us to see a grossly different protein variant.
One describes
how proteins are made, and the
other instructs the cell on
how genes are controlled.
By comparing our genetic make - up to the genomes of mice, chimps and a menagerie of
other species (rats, chickens, dogs, pufferfish, the microscopic worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster and many bacteria), scientists have learned a great deal about
how genes evolve over time, and gained insights into human diseases.
Just
how this process happens is not understood, but scientists suspect that when BRCA1 goes awry, it causes a cascade of malfunctions in
other genes.
The problem of
how a process can be rigidly guided by
genes in one species, while in
others genetics takes a back seat, is discussed in a novel way.
Others have tracked the first few hours of the embryonic development of sea urchins and
other organisms with the goal of seeing
how various transcription factors alter
gene expression over time.
To learn
how Mycobacterium tuberculosis mounts a defense against a drug, Baliga is first looking within the bacterium, identifying the
genes, proteins and
other molecules that interact as the microbe infects a host.
But the potential payoff is enormous: A response map that can display the intertwining routes between
genes and outcomes, as well as
how distant red lights, speed bumps and construction zones play off each
other to shift those paths.
The CREBRF variant appears to be rare in
other populations, but studying
how the
gene works may help researchers better understand obesity.
The latest findings offer new focus points into
how these
genes and
others may be modified to fine - tune a wheat variety for a particular environment, which will result in less crop and food loss due to changing environment.
These
genes are believed to be essential for the normal function of nerve cells, and previous studies have linked these mutations to problems with synaptic function —
how neurons communicate with each
other.
To figure out
how corn and weeds affect each
other's
gene response, Clay and a team of two research associates and a soils expert, planted plots of velvetleaf alone, corn with velvetleaf and corn kept weed - free.
In the last few years, Sweeney, a professor of physiology and medicine at the University of Pennsylvania, and a small cadre of
other researchers have learned
how to create
genes that repair weak, deteriorating, or damaged muscles, bones, tendons, and cartilage in a relatively short period of time.
«The
genes that a taste cell expresses define essentially every aspect of that cell's behavior, from
how it will respond to taste stimuli to
how it will communicate with
other cells,» said study co-leader Brian Lewandowski, PhD, a Monell physiologist.
Now, Mitchum's team is trying to find
how this key
gene might work differently in
other nematode types, like root - knot nematode as part of a new National Science Foundation grant.
At the core of this cell behavior is
how the loss of that single
gene changes activation levels of dozens of
other genes, suppressing
genes associated with metastatic disease and increasing activity of
genes linked to normal tissue.
But while this study has proved that the technique works in a simple organism, it could also be applied to
other bacterial species, yeast or even human cells to find useful information about
how genes are controlled and
how they can be manipulated.
«Now that we know
how calcification happens and what the key nodes are, we know what
genes to look for that might be mutated in
other related forms of cardiovascular disease.»
Gene drive is so different from
other technologies involving genetic modification that it requires a whole new way of thinking about
how to evaluate and regulate it, says Jennifer Kuzma, a natural and social scientist at North Carolina State University (NCSU) in Raleigh who helped organize a February workshop there.
«It's only possible through integrated analysis which allows us to look at this process at a systems level to see
how genes, proteins and
other components work together to regulate lignin production.»
To find out
how the baculovirus does it, and suspecting the involvement of a
gene called egt, Kelli Hoover of Pennsylvania State University in University Park infected some caterpillars with virus that had egt and
others with virus that did not.
Other genes may also shape
how we respond, and our unique personal histories may play a role as well.