Sentences with phrase «how phosphorylation»

Within this broad topic we are particularly interested in characterising (i) the molecular mechanism by which these photoreceptors mediate light - dependent entrainment of the circadian clock, (ii) the components mediating, in a light - quality - dependent fashion, nucleocytoplasmic partitioning of phytochromes and UVR8, (iii) how phosphorylation and sumoylation of these photorecepors and other signalling components modulate red / far - red and UVB - induced signalling, and (iv) to what extent intercellular and cell - autonomous events contribute to phytochrome and UVR8 regulated photomorphogenesis.

Ryan, Abigail Janke and colleagues at Brown showed how phosphorylation disrupts contacts between molecules of FUS.

Searching for those substrates and trying to unravel how phosphorylation affects their activity has kept Hunter and his lab busy for more than three decades.

Not exact matches

Tim Clausen's lab stumbled upon arginine phosphorylation several years ago while studying how certain bacteria cope with adverse conditions.

In a recent study appearing in Nature Publishing Group's Scientific Reports, the researchers focused on the properties of schreibersite and conducted experiments with the mineral to better understand how — in a chemical reaction with the corrosive effects of water called «phosphorylation» — schreibersite could have provided the phosphate important to the emergence of early biological life.

«Now, we need to better understand how this works at the molecular level so we can perhaps design therapeutics to prevent phosphorylation of that site.»

«Phosphorylation helps control how proteins fold and the systems in cells that clear proteins,» explained Finkbeiner, who is a senior investigator at Gladstone.

Such experiments would potentially reveal a role for the proposed phosphorylation event in regulating Oct4 activity and provide further insight into how the Oct4 transcriptional network regulates pluripotency.