The new work examines
how saccharin binds to and deactivates carbonic anhydrase IX, a protein found in some very aggressive cancers.
Using X-ray crystallography, McKenna and his students Jenna Driscoll and Brian Mahon have taken this work a step further by determining
how saccharin binds to carbonic anhydrase IX, and how it or other saccharin - based compounds might be tweaked to enhance this binding and boost its anti-cancer treatment potential.
Not exact matches
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Saccharin?
«It never ceases to amaze me
how a simple molecule, such as
saccharin — something many people put in their coffee everyday — may have untapped uses, including as a possible lead compound to target aggressive cancers,» says Robert McKenna, Ph.D., who is at the University of Florida.